(11 nodes) Mixed, incl. Chromosome passenger complex, and Nuclear microtubule network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107093534	Uncharacterized protein. (188 aa)
	cdca8	Cell division cycle associated 8. (297 aa)
	plk3	Serine/threonine-protein kinase PLK. (667 aa)
	incenp	Uncharacterized protein. (849 aa)
	LOC107090914	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (270 aa)
	intu	Inturned planar cell polarity protein. (946 aa)
	tpx2	TPX2 microtubule nucleation factor. (707 aa)
	espl1	Extra spindle pole bodies like 1, separase. (2168 aa)
	LOC107092931	Aurora kinase B; Belongs to the protein kinase superfamily. (328 aa)
	aurka	Aurora kinase A; Belongs to the protein kinase superfamily. (427 aa)
	LOC107099875	Baculoviral IAP repeat containing 5a. (142 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107090914	LOC107092931	ENSCVAP00000011222	ENSCVAP00000020371	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.670
LOC107090914	LOC107093534	ENSCVAP00000011222	ENSCVAP00000003749	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.702
LOC107090914	LOC107099875	ENSCVAP00000011222	ENSCVAP00000030225	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Baculoviral IAP repeat containing 5a.	0.802
LOC107090914	aurka	ENSCVAP00000011222	ENSCVAP00000024649	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.670
LOC107090914	cdca8	ENSCVAP00000011222	ENSCVAP00000004570	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cell division cycle associated 8.	0.758
LOC107090914	espl1	ENSCVAP00000011222	ENSCVAP00000020190	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Extra spindle pole bodies like 1, separase.	0.810
LOC107090914	incenp	ENSCVAP00000011222	ENSCVAP00000010699	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.619
LOC107090914	intu	ENSCVAP00000011222	ENSCVAP00000011843	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Inturned planar cell polarity protein.	0.849
LOC107090914	plk3	ENSCVAP00000011222	ENSCVAP00000007698	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Serine/threonine-protein kinase PLK.	0.803
LOC107090914	tpx2	ENSCVAP00000011222	ENSCVAP00000017781	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	TPX2 microtubule nucleation factor.	0.470
LOC107092931	LOC107090914	ENSCVAP00000020371	ENSCVAP00000011222	Aurora kinase B; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.670
LOC107092931	LOC107093534	ENSCVAP00000020371	ENSCVAP00000003749	Aurora kinase B; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.768
LOC107092931	LOC107099875	ENSCVAP00000020371	ENSCVAP00000030225	Aurora kinase B; Belongs to the protein kinase superfamily.	Baculoviral IAP repeat containing 5a.	0.937
LOC107092931	cdca8	ENSCVAP00000020371	ENSCVAP00000004570	Aurora kinase B; Belongs to the protein kinase superfamily.	Cell division cycle associated 8.	0.955
LOC107092931	espl1	ENSCVAP00000020371	ENSCVAP00000020190	Aurora kinase B; Belongs to the protein kinase superfamily.	Extra spindle pole bodies like 1, separase.	0.826
LOC107092931	incenp	ENSCVAP00000020371	ENSCVAP00000010699	Aurora kinase B; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.989
LOC107092931	intu	ENSCVAP00000020371	ENSCVAP00000011843	Aurora kinase B; Belongs to the protein kinase superfamily.	Inturned planar cell polarity protein.	0.796
LOC107092931	plk3	ENSCVAP00000020371	ENSCVAP00000007698	Aurora kinase B; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase PLK.	0.863
LOC107092931	tpx2	ENSCVAP00000020371	ENSCVAP00000017781	Aurora kinase B; Belongs to the protein kinase superfamily.	TPX2 microtubule nucleation factor.	0.953
LOC107093534	LOC107090914	ENSCVAP00000003749	ENSCVAP00000011222	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.702