(15 nodes) Mixed, incl. Mitogen-activated protein (MAP) kinase, conserved site, and Histone H3-S10 phosphorylation network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dusp8	Dual specificity phosphatase 8a. (679 aa)
	LOC107090582	MADS-box domain-containing protein. (464 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	LOC107101432	Mitogen-activated protein kinase. (360 aa)
	LOC107087504	Mitogen-activated protein kinase. (357 aa)
	LOC107101186	Mitogen-activated protein kinase. (379 aa)
	mapk1	Mitogen-activated protein kinase. (351 aa)
	LOC107088576	Mitogen-activated protein kinase. (364 aa)
	LOC107095820	Ribosomal protein S6 kinase. (803 aa)
	creb5	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (494 aa)
	LOC107097013	ETS transcription factor ELK1. (547 aa)
	LOC107082492	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	LOC107091383	Ribosomal protein S6 kinase. (782 aa)
	atf2	Activating transcription factor 2. (513 aa)
	mef2c	Myocyte enhancer factor 2cb. (526 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107082492	LOC107090582	ENSCVAP00000028704	ENSCVAP00000002572	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MADS-box domain-containing protein.	0.951
LOC107082492	LOC107091383	ENSCVAP00000028704	ENSCVAP00000030209	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Ribosomal protein S6 kinase.	0.950
LOC107082492	LOC107095820	ENSCVAP00000028704	ENSCVAP00000019287	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Ribosomal protein S6 kinase.	0.950
LOC107082492	LOC107097013	ENSCVAP00000028704	ENSCVAP00000028580	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	ETS transcription factor ELK1.	0.944
LOC107082492	LOC107101186	ENSCVAP00000028704	ENSCVAP00000013006	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.933
LOC107082492	atf2	ENSCVAP00000028704	ENSCVAP00000030400	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Activating transcription factor 2.	0.963
LOC107082492	creb5	ENSCVAP00000028704	ENSCVAP00000026562	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.562
LOC107082492	dusp8	ENSCVAP00000028704	ENSCVAP00000001942	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity phosphatase 8a.	0.894
LOC107082492	map2k1	ENSCVAP00000028704	ENSCVAP00000004697	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.736
LOC107082492	mapk1	ENSCVAP00000028704	ENSCVAP00000015363	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.933
LOC107082492	mef2c	ENSCVAP00000028704	ENSCVAP00000031925	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Myocyte enhancer factor 2cb.	0.962
LOC107087504	LOC107090582	ENSCVAP00000010645	ENSCVAP00000002572	Mitogen-activated protein kinase.	MADS-box domain-containing protein.	0.951
LOC107087504	LOC107091383	ENSCVAP00000010645	ENSCVAP00000030209	Mitogen-activated protein kinase.	Ribosomal protein S6 kinase.	0.950
LOC107087504	LOC107095820	ENSCVAP00000010645	ENSCVAP00000019287	Mitogen-activated protein kinase.	Ribosomal protein S6 kinase.	0.950
LOC107087504	LOC107097013	ENSCVAP00000010645	ENSCVAP00000028580	Mitogen-activated protein kinase.	ETS transcription factor ELK1.	0.944
LOC107087504	LOC107101186	ENSCVAP00000010645	ENSCVAP00000013006	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.933
LOC107087504	atf2	ENSCVAP00000010645	ENSCVAP00000030400	Mitogen-activated protein kinase.	Activating transcription factor 2.	0.963
LOC107087504	creb5	ENSCVAP00000010645	ENSCVAP00000026562	Mitogen-activated protein kinase.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.562
LOC107087504	dusp8	ENSCVAP00000010645	ENSCVAP00000001942	Mitogen-activated protein kinase.	Dual specificity phosphatase 8a.	0.849
LOC107087504	map2k1	ENSCVAP00000010645	ENSCVAP00000004697	Mitogen-activated protein kinase.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.732