(22 nodes) Mixed, incl. Protein hydroxylation, and Collagen biosynthetic process network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ppib	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	P3H4	Prolyl 3-hydroxylase family member 4 (non-enzymatic). (435 aa)
	ENSCVAP00000008612	Fibrillar collagen NC1 domain-containing protein. (112 aa)
	serpinf1	SERPIN domain-containing protein; Belongs to the serpin family. (405 aa)
	LOC107086413	Protein disulfide-isomerase. (584 aa)
	p3h4	Prolyl 3-hydroxylase family member 4 (non-enzymatic). (426 aa)
	LOC107097023	Peptidylprolyl isomerase. (563 aa)
	p3h1	Fe2OG dioxygenase domain-containing protein. (739 aa)
	p4ha3	Prolyl 4-hydroxylase, alpha polypeptide III. (541 aa)
	ENSCVAP00000015961	VWFA domain-containing protein. (291 aa)
	ENSCVAP00000015984	Uncharacterized protein. (427 aa)
	serpinh1	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (405 aa)
	LOC107105197	SERPIN domain-containing protein; Belongs to the serpin family. (424 aa)
	p3h3	Prolyl 3-hydroxylase 3. (734 aa)
	LOC107099764	Peptidylprolyl isomerase. (568 aa)
	ENSCVAP00000021953	Fibrillar collagen NC1 domain-containing protein. (117 aa)
	LOC107102594	Interferon induced transmembrane protein 5. (142 aa)
	crtap	Cartilage associated protein. (396 aa)
	col6a1	Collagen, type VI, alpha 1. (944 aa)
	col6a2	Collagen, type VI, alpha 2. (1011 aa)
	ppic	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (208 aa)
	p3h2	Prolyl 3-hydroxylase 2. (682 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000008612	LOC107086413	ENSCVAP00000008612	ENSCVAP00000013545	Fibrillar collagen NC1 domain-containing protein.	Protein disulfide-isomerase.	0.439
ENSCVAP00000008612	LOC107105197	ENSCVAP00000008612	ENSCVAP00000016830	Fibrillar collagen NC1 domain-containing protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.446
ENSCVAP00000008612	p4ha3	ENSCVAP00000008612	ENSCVAP00000015045	Fibrillar collagen NC1 domain-containing protein.	Prolyl 4-hydroxylase, alpha polypeptide III.	0.424
ENSCVAP00000008612	ppib	ENSCVAP00000008612	ENSCVAP00000000492	Fibrillar collagen NC1 domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.470
ENSCVAP00000008612	serpinh1	ENSCVAP00000008612	ENSCVAP00000016183	Fibrillar collagen NC1 domain-containing protein.	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family.	0.446
ENSCVAP00000015961	ENSCVAP00000015984	ENSCVAP00000015961	ENSCVAP00000015984	VWFA domain-containing protein.	Uncharacterized protein.	0.872
ENSCVAP00000015961	LOC107086413	ENSCVAP00000015961	ENSCVAP00000013545	VWFA domain-containing protein.	Protein disulfide-isomerase.	0.454
ENSCVAP00000015961	col6a1	ENSCVAP00000015961	ENSCVAP00000028473	VWFA domain-containing protein.	Collagen, type VI, alpha 1.	0.916
ENSCVAP00000015961	p3h1	ENSCVAP00000015961	ENSCVAP00000014236	VWFA domain-containing protein.	Fe2OG dioxygenase domain-containing protein.	0.407
ENSCVAP00000015961	p3h2	ENSCVAP00000015961	ENSCVAP00000031309	VWFA domain-containing protein.	Prolyl 3-hydroxylase 2.	0.407
ENSCVAP00000015961	p3h3	ENSCVAP00000015961	ENSCVAP00000019538	VWFA domain-containing protein.	Prolyl 3-hydroxylase 3.	0.407
ENSCVAP00000015961	p4ha3	ENSCVAP00000015961	ENSCVAP00000015045	VWFA domain-containing protein.	Prolyl 4-hydroxylase, alpha polypeptide III.	0.449
ENSCVAP00000015961	ppib	ENSCVAP00000015961	ENSCVAP00000000492	VWFA domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.500
ENSCVAP00000015961	ppic	ENSCVAP00000015961	ENSCVAP00000030172	VWFA domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.449
ENSCVAP00000015984	ENSCVAP00000015961	ENSCVAP00000015984	ENSCVAP00000015961	Uncharacterized protein.	VWFA domain-containing protein.	0.872
ENSCVAP00000015984	LOC107086413	ENSCVAP00000015984	ENSCVAP00000013545	Uncharacterized protein.	Protein disulfide-isomerase.	0.454
ENSCVAP00000015984	col6a1	ENSCVAP00000015984	ENSCVAP00000028473	Uncharacterized protein.	Collagen, type VI, alpha 1.	0.916
ENSCVAP00000015984	p3h1	ENSCVAP00000015984	ENSCVAP00000014236	Uncharacterized protein.	Fe2OG dioxygenase domain-containing protein.	0.407
ENSCVAP00000015984	p3h2	ENSCVAP00000015984	ENSCVAP00000031309	Uncharacterized protein.	Prolyl 3-hydroxylase 2.	0.407
ENSCVAP00000015984	p3h3	ENSCVAP00000015984	ENSCVAP00000019538	Uncharacterized protein.	Prolyl 3-hydroxylase 3.	0.407