(47 nodes) Mixed, incl. Protein-lipid complex, and Plasma lipoprotein clearance network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dab2	DAB adaptor protein 2. (767 aa)
	apof	Apolipoprotein F. (440 aa)
	ENSCVAP00000000643	EGF-like domain-containing protein. (129 aa)
	ENSCVAP00000000671	Uncharacterized protein. (1167 aa)
	ENSCVAP00000000678	Uncharacterized protein. (697 aa)
	LOC107081658	Apolipoprotein Bb, tandem duplicate 2. (3721 aa)
	cetp	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (498 aa)
	ENSCVAP00000001456	Vitellogenin domain-containing protein. (808 aa)
	ENSCVAP00000002020	Vitellogenin domain-containing protein. (110 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (669 aa)
	LOC107094062	DAB adaptor protein 1a. (552 aa)
	LOC107097923	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor. (974 aa)
	LOC107095595	Si:dkey-19b23.8. (221 aa)
	LOC107103178	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (187 aa)
	LOC107102526	Paraoxonase 1. (355 aa)
	LOC107102544	Uncharacterized protein. (357 aa)
	ENSCVAP00000007853	Uncharacterized protein. (301 aa)
	LOC107095516	Apolipoprotein Ea. (271 aa)
	mttp	Microsomal triglyceride transfer protein. (889 aa)
	pltp	Phospholipid transfer protein. (491 aa)
	LOC107090951	Si:dkey-88l16.3. (1286 aa)
	LOC107083615	DAB adaptor protein 1b. (416 aa)
	LOC107080755	Low density lipoprotein receptor a. (859 aa)
	ENSCVAP00000013067	Uncharacterized protein. (237 aa)
	apoa4	Apolipoprotein A-Ib. (263 aa)
	LOC107098745	Apolipoprotein Ba. (4081 aa)
	LOC107093644	Low density lipoprotein receptor adaptor protein 1a. (307 aa)
	LOC107082950	Apolipoprotein Eb. (335 aa)
	LOC107082965	Uncharacterized protein. (255 aa)
	LOC107082973	Uncharacterized protein. (255 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (323 aa)
	ENSCVAP00000017723	Low density lipoprotein receptor-related protein 2b. (2130 aa)
	LOC107083425	Uncharacterized protein. (380 aa)
	ENSCVAP00000019553	Vitellogenin domain-containing protein. (429 aa)
	lrp3	Low density lipoprotein receptor-related protein 3. (791 aa)
	ENSCVAP00000020301	EGF-like domain-containing protein. (1134 aa)
	LOC107099044	Si:ch73-278m9.1. (324 aa)
	ENSCVAP00000020812	Uncharacterized protein. (420 aa)
	LOC107082788	Low density lipoprotein receptor b. (857 aa)
	LOC107087223	Vitellogenin 5. (1625 aa)
	ENSCVAP00000021184	VWFD domain-containing protein. (129 aa)
	ENSCVAP00000021193	VWFD domain-containing protein. (133 aa)
	ENSCVAP00000021287	Uncharacterized protein. (246 aa)
	RELN	Reelin. (3062 aa)
	vldlr	Very low density lipoprotein receptor. (697 aa)
	ENSCVAP00000030193	Uncharacterized protein. (83 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (549 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000000643	ENSCVAP00000000671	ENSCVAP00000000643	ENSCVAP00000000671	EGF-like domain-containing protein.	Uncharacterized protein.	0.858
ENSCVAP00000000643	ENSCVAP00000000678	ENSCVAP00000000643	ENSCVAP00000000678	EGF-like domain-containing protein.	Uncharacterized protein.	0.895
ENSCVAP00000000643	ENSCVAP00000013067	ENSCVAP00000000643	ENSCVAP00000013067	EGF-like domain-containing protein.	Uncharacterized protein.	0.466
ENSCVAP00000000643	ENSCVAP00000020301	ENSCVAP00000000643	ENSCVAP00000020301	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.863
ENSCVAP00000000643	LOC107082788	ENSCVAP00000000643	ENSCVAP00000021128	EGF-like domain-containing protein.	Low density lipoprotein receptor b.	0.422
ENSCVAP00000000643	LOC107082950	ENSCVAP00000000643	ENSCVAP00000015717	EGF-like domain-containing protein.	Apolipoprotein Eb.	0.503
ENSCVAP00000000643	LOC107083615	ENSCVAP00000000643	ENSCVAP00000011635	EGF-like domain-containing protein.	DAB adaptor protein 1b.	0.488
ENSCVAP00000000643	LOC107093644	ENSCVAP00000000643	ENSCVAP00000015162	EGF-like domain-containing protein.	Low density lipoprotein receptor adaptor protein 1a.	0.481
ENSCVAP00000000643	LOC107094062	ENSCVAP00000000643	ENSCVAP00000002947	EGF-like domain-containing protein.	DAB adaptor protein 1a.	0.488
ENSCVAP00000000643	LOC107097923	ENSCVAP00000000643	ENSCVAP00000004631	EGF-like domain-containing protein.	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.	0.417
ENSCVAP00000000643	RELN	ENSCVAP00000000643	ENSCVAP00000022277	EGF-like domain-containing protein.	Reelin.	0.620
ENSCVAP00000000643	dab2	ENSCVAP00000000643	ENSCVAP00000000116	EGF-like domain-containing protein.	DAB adaptor protein 2.	0.571
ENSCVAP00000000643	ldlrap1	ENSCVAP00000000643	ENSCVAP00000016700	EGF-like domain-containing protein.	Low density lipoprotein receptor adaptor protein 1b.	0.613
ENSCVAP00000000643	pcsk9	ENSCVAP00000000643	ENSCVAP00000002780	EGF-like domain-containing protein.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.591
ENSCVAP00000000643	vldlr	ENSCVAP00000000643	ENSCVAP00000023350	EGF-like domain-containing protein.	Very low density lipoprotein receptor.	0.424
ENSCVAP00000000671	ENSCVAP00000000643	ENSCVAP00000000671	ENSCVAP00000000643	Uncharacterized protein.	EGF-like domain-containing protein.	0.858
ENSCVAP00000000671	ENSCVAP00000013067	ENSCVAP00000000671	ENSCVAP00000013067	Uncharacterized protein.	Uncharacterized protein.	0.466
ENSCVAP00000000671	LOC107082950	ENSCVAP00000000671	ENSCVAP00000015717	Uncharacterized protein.	Apolipoprotein Eb.	0.503
ENSCVAP00000000671	LOC107083615	ENSCVAP00000000671	ENSCVAP00000011635	Uncharacterized protein.	DAB adaptor protein 1b.	0.488
ENSCVAP00000000671	LOC107093644	ENSCVAP00000000671	ENSCVAP00000015162	Uncharacterized protein.	Low density lipoprotein receptor adaptor protein 1a.	0.481