(78 nodes) Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpl7l1	Ribosomal protein L7-like 1. (247 aa)
	rps26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (129 aa)
	arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1. (203 aa)
	rps23	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	RPS29	Ribosomal protein S29. (60 aa)
	rps27a	Ribosomal protein S27a. (181 aa)
	rpl39	Ribosomal protein L39. (84 aa)
	fance	FA complementation group E. (509 aa)
	rpl4	Ribosomal protein L4. (377 aa)
	rpl9	Ribosomal protein L9. (192 aa)
	rpsa	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (309 aa)
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (198 aa)
	rpl21	Ribosomal protein L21. (149 aa)
	rps9	Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
	rpl18	Ribosomal protein L18. (189 aa)
	LOC107081314	Ribosomal protein S5. (122 aa)
	rplp2	Ribosomal protein, large P2; Belongs to the eukaryotic ribosomal protein P1/P2 family. (115 aa)
	rps6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
	RPL5-2	Ribosomal protein L5b. (284 aa)
	rpl15	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
	rpl32	Ribosomal protein L32. (135 aa)
	RPL19-2	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (196 aa)
	rps28	Ribosomal protein S28. (69 aa)
	rpl36	60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (121 aa)
	rps4x	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	LOC107086468	Ribosomal protein L26. (145 aa)
	rps10	Ribosomal protein S10. (166 aa)
	rps13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	RPL27A	Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family. (148 aa)
	rps24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (132 aa)
	rpl27	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (136 aa)
	rps21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa)
	rpl37a	Ribosomal protein L37a. (92 aa)
	ENSCVAP00000013380	Uncharacterized protein. (90 aa)
	LOC107090794	Ribosomal protein, large P2, like; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
	rpl24	Ribosomal protein L24. (163 aa)
	rpl34	Ribosomal protein L34. (117 aa)
	rpl35	Ribosomal protein L35. (125 aa)
	LOC107084035	40S ribosomal protein S27. (84 aa)
	rps12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (187 aa)
	RPS19	Ribosomal protein S19. (152 aa)
	rps3a	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (266 aa)
	rps14	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	rpl13	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa)
	rack1	Receptor for activated C kinase 1. (317 aa)
	rpl18a	60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family. (176 aa)
	rpl17	Ribosomal protein L17; Belongs to the universal ribosomal protein uL22 family. (184 aa)
	rpl28	Ribosomal protein L28. (137 aa)
	rpl37	Ribosomal protein L37; Binds to the 23S rRNA. (97 aa)
	rpl35a	Ribosomal protein L35a. (110 aa)
	rpl14	Ribosomal protein L14. (144 aa)
	rplp0	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (314 aa)
	rps2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (490 aa)
	RPL3L	Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family. (395 aa)
	rplp1	Ribosomal protein, large, P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (112 aa)
	LOC107093415	Ribosomal protein L36A; Belongs to the eukaryotic ribosomal protein eL42 family. (143 aa)
	LOC107086545	Ribosomal protein S17. (134 aa)
	rps25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (123 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	rpl13a	Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family. (183 aa)
	ENSCVAP00000025919	Uncharacterized protein. (113 aa)
	rpl10	Ribosomal protein L10. (215 aa)
	rps17	Uncharacterized protein. (166 aa)
	LOC107097254	Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (418 aa)
	fau	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (133 aa)
	RPL7A	Ribosomal protein L7a. (274 aa)
	rpl8	Ribosomal protein L8. (257 aa)
	rps16	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	LOC107084670	Ribosomal protein S19. (146 aa)
	rps8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (238 aa)
	rpl6	Ribosomal protein L6. (259 aa)
	rps7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (176 aa)
	ENSCVAP00000031317	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
	ENSCVAP00000031592	annotation not available (64 aa)
	rpl12	Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family. (165 aa)
	rpl30	Ribosomal protein L30. (116 aa)
	rpl29	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (106 aa)
	ENSCVAP00000032796	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (175 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000013380	ENSCVAP00000025919	ENSCVAP00000013380	ENSCVAP00000025919	Uncharacterized protein.	Uncharacterized protein.	0.978
ENSCVAP00000013380	ENSCVAP00000031317	ENSCVAP00000013380	ENSCVAP00000031317	Uncharacterized protein.	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	0.995
ENSCVAP00000013380	ENSCVAP00000031592	ENSCVAP00000013380	ENSCVAP00000031592	Uncharacterized protein.	annotation not available	0.954
ENSCVAP00000013380	ENSCVAP00000032796	ENSCVAP00000013380	ENSCVAP00000032796	Uncharacterized protein.	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.	0.944
ENSCVAP00000013380	LOC107081314	ENSCVAP00000013380	ENSCVAP00000007091	Uncharacterized protein.	Ribosomal protein S5.	0.944
ENSCVAP00000013380	LOC107084035	ENSCVAP00000013380	ENSCVAP00000015069	Uncharacterized protein.	40S ribosomal protein S27.	0.950
ENSCVAP00000013380	LOC107084670	ENSCVAP00000013380	ENSCVAP00000029297	Uncharacterized protein.	Ribosomal protein S19.	0.975
ENSCVAP00000013380	LOC107086468	ENSCVAP00000013380	ENSCVAP00000011081	Uncharacterized protein.	Ribosomal protein L26.	0.996
ENSCVAP00000013380	LOC107086545	ENSCVAP00000013380	ENSCVAP00000022321	Uncharacterized protein.	Ribosomal protein S17.	0.987
ENSCVAP00000013380	LOC107090794	ENSCVAP00000013380	ENSCVAP00000013450	Uncharacterized protein.	Ribosomal protein, large P2, like; Belongs to the eukaryotic ribosomal protein P1/P2 family.	0.964
ENSCVAP00000013380	LOC107093415	ENSCVAP00000013380	ENSCVAP00000022162	Uncharacterized protein.	Ribosomal protein L36A; Belongs to the eukaryotic ribosomal protein eL42 family.	0.992
ENSCVAP00000013380	LOC107097254	ENSCVAP00000013380	ENSCVAP00000028189	Uncharacterized protein.	Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.	0.968
ENSCVAP00000013380	RPL19	ENSCVAP00000013380	ENSCVAP00000006366	Uncharacterized protein.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.975
ENSCVAP00000013380	RPL19-2	ENSCVAP00000013380	ENSCVAP00000010501	Uncharacterized protein.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.975
ENSCVAP00000013380	RPL27A	ENSCVAP00000013380	ENSCVAP00000012669	Uncharacterized protein.	Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.	0.994
ENSCVAP00000013380	RPL3L	ENSCVAP00000013380	ENSCVAP00000020991	Uncharacterized protein.	Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family.	0.968
ENSCVAP00000013380	RPL5-2	ENSCVAP00000013380	ENSCVAP00000010029	Uncharacterized protein.	Ribosomal protein L5b.	0.980
ENSCVAP00000013380	RPL7A	ENSCVAP00000013380	ENSCVAP00000028616	Uncharacterized protein.	Ribosomal protein L7a.	0.994
ENSCVAP00000013380	RPS19	ENSCVAP00000013380	ENSCVAP00000015792	Uncharacterized protein.	Ribosomal protein S19.	0.951
ENSCVAP00000013380	RPS29	ENSCVAP00000013380	ENSCVAP00000003444	Uncharacterized protein.	Ribosomal protein S29.	0.990