(76 nodes) Mixed, incl. BLOC complex, and Sodium Bile acid symporter family network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCVAP00000000510	Uncharacterized protein. (79 aa)
	abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11a. (1212 aa)
	LOC107082017	Solute carrier family 15 member 1a. (733 aa)
	hps1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (674 aa)
	hps3	HPS3 biogenesis of lysosomal organelles complex 2 subunit 1. (1057 aa)
	HPS6	HPS6 biogenesis of lysosomal organelles complex 2 subunit 3. (836 aa)
	lyst	Lysosomal trafficking regulator. (2550 aa)
	ENSCVAP00000002342	Uncharacterized protein. (534 aa)
	bloc1s5	Biogenesis of lysosomal organelles complex-1, subunit 5, muted. (168 aa)
	LOC107098406	Divergent protein kinase domain 1Aa. (455 aa)
	plekhd1	Pleckstrin homology domain containing, family D (with coiled-coil domains) member 1. (481 aa)
	Map4k5	Protein kinase domain-containing protein. (186 aa)
	LOC107083821	Elastase 3 like; Belongs to the peptidase S1 family. (269 aa)
	slc10a7	Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (341 aa)
	SLC10A1	Solute carrier family 10 member 1. (363 aa)
	hps4	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (597 aa)
	LOC107083124	Uncharacterized protein. (252 aa)
	LOC107086983	Uncharacterized protein. (328 aa)
	ENSCVAP00000009761	CNH domain-containing protein. (357 aa)
	amn	Amnion associated transmembrane protein. (472 aa)
	LOC107090978	Coiled-coil domain containing 88B. (1304 aa)
	hps5	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1058 aa)
	ENSCVAP00000011377	CNH domain-containing protein. (292 aa)
	borcs6	Si:dkey-72l14.4. (440 aa)
	Adra2c	Adrenoceptor alpha 2C. (436 aa)
	cacng5	Calcium channel, voltage-dependent, gamma subunit 5a. (277 aa)
	LOC107101754	Uncharacterized protein. (1488 aa)
	Map4k4	Protein kinase domain-containing protein. (539 aa)
	RAB26	RAB26, member RAS oncogene family. (236 aa)
	ENSCVAP00000013117	Sushi domain containing 1. (604 aa)
	LOC107091990	Zgc:162171. (227 aa)
	kif1b	Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1785 aa)
	gpr31	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (342 aa)
	bloc1s1	Biogenesis of lysosomal organelles complex-1, subunit 1. (125 aa)
	ENSCVAP00000015386	Uncharacterized protein. (345 aa)
	snapin	SNAP associated protein. (129 aa)
	LOC107082386	Hairy-related 5. (197 aa)
	LOC107087911	RAB38b, member of RAS oncogene family. (218 aa)
	tbc1d8	Rab-GAP TBC domain-containing protein. (1111 aa)
	tnfaip8l1	Tumor necrosis factor, alpha-induced protein 8-like 1. (186 aa)
	borcs5	BLOC-1 related complex subunit 5. (197 aa)
	LOC107103953	Uncharacterized protein. (282 aa)
	LOC107087826	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (244 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (220 aa)
	bloc1s2	Biogenesis of lysosomal organelles complex-1, subunit 2. (179 aa)
	ENSCVAP00000021825	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (386 aa)
	tbc1d9b	TBC1 domain family, member 9 (with GRAM domain). (1205 aa)
	tmigd1	Transmembrane and immunoglobulin domain containing 1. (277 aa)
	LOC107088855	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (266 aa)
	clrn3	Clarin 3. (231 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	ADRA2C	Adrenoceptor alpha 2C. (432 aa)
	borcs8	BLOC-1 related complex subunit 8. (128 aa)
	LOC107082484	Solute carrier family 10 member 2. (358 aa)
	LOC107082477	Solute carrier family 10 member 2. (358 aa)
	cnp	Uncharacterized protein. (707 aa)
	kifbp	Kif1 binding protein. (660 aa)
	bloc1s6	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (171 aa)
	LOC107103689	Transcobalamin II. (426 aa)
	ENSCVAP00000025596	BAAT_C domain-containing protein. (218 aa)
	ENSCVAP00000025617	Uncharacterized protein. (256 aa)
	cdcp2	CUB domain containing protein 2. (462 aa)
	ENSCVAP00000026712	Uncharacterized protein. (205 aa)
	LOC107090911	Zgc:112285; Belongs to the peptidase S1 family. (319 aa)
	LOC107084200	RAB38c, member of RAS oncogene family. (206 aa)
	ENSCVAP00000028561	DBB domain-containing protein. (563 aa)
	ENSCVAP00000029016	Hydroxycarboxylic acid receptor 1-3; Belongs to the G-protein coupled receptor 1 family. (315 aa)
	slc10a1	Solute carrier family 10 member 1. (337 aa)
	LOC107103448	Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (268 aa)
	borcs7	BLOC-1 related complex subunit 7. (103 aa)
	LOC107084893	Fatty acid binding protein 10a, liver basic. (126 aa)
	bloc1s3	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (197 aa)
	LOC107089090	Coiled-coil domain containing 88Aa. (1278 aa)
	FABP6	Fatty acid binding protein 6. (125 aa)
	mink1	Misshapen-like kinase 1. (1204 aa)
	Slc10a3	Solute carrier family 10 member 3. (435 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA2C	LOC107090911	ENSCVAP00000023848	ENSCVAP00000027446	Adrenoceptor alpha 2C.	Zgc:112285; Belongs to the peptidase S1 family.	0.406
ADRA2C	gpr31	ENSCVAP00000023848	ENSCVAP00000014363	Adrenoceptor alpha 2C.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.489
Adra2c	LOC107090911	ENSCVAP00000011647	ENSCVAP00000027446	Adrenoceptor alpha 2C.	Zgc:112285; Belongs to the peptidase S1 family.	0.406
Adra2c	gpr31	ENSCVAP00000011647	ENSCVAP00000014363	Adrenoceptor alpha 2C.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.489
ENSCVAP00000000510	LOC107087826	ENSCVAP00000000510	ENSCVAP00000019731	Uncharacterized protein.	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino.	0.527
ENSCVAP00000000510	bloc1s1	ENSCVAP00000000510	ENSCVAP00000015066	Uncharacterized protein.	Biogenesis of lysosomal organelles complex-1, subunit 1.	0.798
ENSCVAP00000000510	bloc1s2	ENSCVAP00000000510	ENSCVAP00000021728	Uncharacterized protein.	Biogenesis of lysosomal organelles complex-1, subunit 2.	0.573
ENSCVAP00000000510	bloc1s3	ENSCVAP00000000510	ENSCVAP00000030221	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	0.592
ENSCVAP00000000510	bloc1s6	ENSCVAP00000000510	ENSCVAP00000025434	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	0.754
ENSCVAP00000000510	dtnbp1	ENSCVAP00000000510	ENSCVAP00000019766	Uncharacterized protein.	Dystrobrevin binding protein 1b.	0.723
ENSCVAP00000000510	hps3	ENSCVAP00000000510	ENSCVAP00000001669	Uncharacterized protein.	HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.	0.491
ENSCVAP00000000510	hps5	ENSCVAP00000000510	ENSCVAP00000010802	Uncharacterized protein.	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	0.545
ENSCVAP00000000510	snapin	ENSCVAP00000000510	ENSCVAP00000015598	Uncharacterized protein.	SNAP associated protein.	0.691
ENSCVAP00000002342	LOC107090978	ENSCVAP00000002342	ENSCVAP00000010370	Uncharacterized protein.	Coiled-coil domain containing 88B.	0.409
ENSCVAP00000002342	cnp	ENSCVAP00000002342	ENSCVAP00000024933	Uncharacterized protein.	Uncharacterized protein.	0.629
ENSCVAP00000002342	dtnbp1	ENSCVAP00000002342	ENSCVAP00000019766	Uncharacterized protein.	Dystrobrevin binding protein 1b.	0.639
ENSCVAP00000009761	LOC107101754	ENSCVAP00000009761	ENSCVAP00000012032	CNH domain-containing protein.	Uncharacterized protein.	0.900
ENSCVAP00000009761	Map4k4	ENSCVAP00000009761	ENSCVAP00000012188	CNH domain-containing protein.	Protein kinase domain-containing protein.	0.891
ENSCVAP00000009761	Map4k5	ENSCVAP00000009761	ENSCVAP00000004933	CNH domain-containing protein.	Protein kinase domain-containing protein.	0.847
ENSCVAP00000011377	Map4k4	ENSCVAP00000011377	ENSCVAP00000012188	CNH domain-containing protein.	Protein kinase domain-containing protein.	0.894