32 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	acaca	Acetyl-CoA carboxylase alpha. (2338 aa)
	PMVK	Phosphomevalonate kinase. (198 aa)
	LOC107099763	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1102 aa)
	aass	Aminoadipate-semialdehyde synthase. (877 aa)
	LOC107089440	Acetyl-coenzyme A synthetase. (673 aa)
	tdo2	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (405 aa)
	acss2	Acyl-CoA synthetase short chain family member 2. (698 aa)
	nudt7	Nudix (nucleoside diphosphate linked moiety X)-type motif 7. (245 aa)
	pdhx	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (491 aa)
	pipox	Pipecolic acid oxidase. (388 aa)
	ENSCVAP00000007624	Uncharacterized protein. (105 aa)
	LOC107086986	Uncharacterized protein. (670 aa)
	LOC107100048	Acetyl-CoA carboxylase beta. (2296 aa)
	dlat	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (633 aa)
	aadat	Aminoadipate aminotransferase. (425 aa)
	ENSCVAP00000012342	Uncharacterized protein. (97 aa)
	nudt8	Nudix hydrolase domain-containing protein. (409 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
	LOC107092408	Dihydrolipoamide S-succinyltransferase. (461 aa)
	pdhb	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
	acss1	Acetyl-coenzyme A synthetase. (680 aa)
	LOC107095810	Uncharacterized protein. (263 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	ENSCVAP00000022899	E1_dh domain-containing protein. (174 aa)
	ENSCVAP00000024914	Citrate_bind domain-containing protein. (477 aa)
	mlycd	Malonyl-CoA decarboxylase. (504 aa)
	ppcs	Phosphopantothenoylcysteine synthetase. (317 aa)
	mpc2	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (126 aa)
	LOC107081772	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (450 aa)
	LOC107104610	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (394 aa)
	LOC107102750	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (554 aa)
	DLST	Dihydrolipoamide S-succinyltransferase. (423 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLST	ENSCVAP00000007624	ENSCVAP00000032644	ENSCVAP00000007624	Dihydrolipoamide S-succinyltransferase.	Uncharacterized protein.	0.750
DLST	ENSCVAP00000022899	ENSCVAP00000032644	ENSCVAP00000022899	Dihydrolipoamide S-succinyltransferase.	E1_dh domain-containing protein.	0.732
DLST	ENSCVAP00000024914	ENSCVAP00000032644	ENSCVAP00000024914	Dihydrolipoamide S-succinyltransferase.	Citrate_bind domain-containing protein.	0.750
DLST	LOC107081772	ENSCVAP00000032644	ENSCVAP00000028861	Dihydrolipoamide S-succinyltransferase.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.795
DLST	LOC107086986	ENSCVAP00000032644	ENSCVAP00000009081	Dihydrolipoamide S-succinyltransferase.	Uncharacterized protein.	0.705
DLST	LOC107089440	ENSCVAP00000032644	ENSCVAP00000002508	Dihydrolipoamide S-succinyltransferase.	Acetyl-coenzyme A synthetase.	0.418
DLST	LOC107099763	ENSCVAP00000032644	ENSCVAP00000002297	Dihydrolipoamide S-succinyltransferase.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.750
DLST	LOC107104610	ENSCVAP00000032644	ENSCVAP00000030003	Dihydrolipoamide S-succinyltransferase.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.796
DLST	acss1	ENSCVAP00000032644	ENSCVAP00000019293	Dihydrolipoamide S-succinyltransferase.	Acetyl-coenzyme A synthetase.	0.418
DLST	acss2	ENSCVAP00000032644	ENSCVAP00000005532	Dihydrolipoamide S-succinyltransferase.	Acyl-CoA synthetase short chain family member 2.	0.418
DLST	dlat	ENSCVAP00000032644	ENSCVAP00000010939	Dihydrolipoamide S-succinyltransferase.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.901
DLST	pdhb	ENSCVAP00000032644	ENSCVAP00000019277	Dihydrolipoamide S-succinyltransferase.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.968
DLST	pdhx	ENSCVAP00000032644	ENSCVAP00000006905	Dihydrolipoamide S-succinyltransferase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.903
ENSCVAP00000007624	DLST	ENSCVAP00000007624	ENSCVAP00000032644	Uncharacterized protein.	Dihydrolipoamide S-succinyltransferase.	0.750
ENSCVAP00000007624	ENSCVAP00000024914	ENSCVAP00000007624	ENSCVAP00000024914	Uncharacterized protein.	Citrate_bind domain-containing protein.	0.467
ENSCVAP00000007624	LOC107092408	ENSCVAP00000007624	ENSCVAP00000018973	Uncharacterized protein.	Dihydrolipoamide S-succinyltransferase.	0.750
ENSCVAP00000007624	LOC107100048	ENSCVAP00000007624	ENSCVAP00000009838	Uncharacterized protein.	Acetyl-CoA carboxylase beta.	0.458
ENSCVAP00000007624	acaca	ENSCVAP00000007624	ENSCVAP00000001382	Uncharacterized protein.	Acetyl-CoA carboxylase alpha.	0.458
ENSCVAP00000007624	dlat	ENSCVAP00000007624	ENSCVAP00000010939	Uncharacterized protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.771
ENSCVAP00000007624	pdhb	ENSCVAP00000007624	ENSCVAP00000019277	Uncharacterized protein.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.454