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| | ing4 | Inhibitor of growth protein. (249 aa) |
| | LOC107082340 | SET domain and mariner transposase fusion gene. (283 aa) |
| | chaf1a | Chromatin assembly factor 1, subunit A (p150). (727 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (878 aa) |
| | LOC107098150 | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (540 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (884 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (567 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | DONSON | Downstream neighbor of SON. (533 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (692 aa) |
| | wdr18 | WD repeat domain 18. (424 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | Zpr1 | ZPR1 zinc finger. (223 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (671 aa) |
| | NFIB | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (560 aa) |
| | LOC107094846 | HD domain-containing protein. (424 aa) |
| | polg2 | Polymerase (DNA directed), gamma 2, accessory subunit. (380 aa) |
| | recql5 | RecQ helicase-like 5. (1010 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | cdc6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (569 aa) |
| | LOC107098236 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (507 aa) |
| | rbbp4 | Retinoblastoma binding protein 4. (424 aa) |
| | pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (604 aa) |
| | dna2 | DNA replication helicase/nuclease 2. (1358 aa) |
| | cinp | Cyclin-dependent kinase 2 interacting protein. (209 aa) |
| | ENSCVAP00000025174 | HD domain-containing protein. (393 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1503 aa) |
| | LOC107089962 | Zgc:110269. (342 aa) |
| | recql4 | RecQ helicase-like 4. (942 aa) |
| | grwd1 | Glutamate-rich WD repeat containing 1. (451 aa) |
| | lig4 | DNA ligase. (908 aa) |
| | rfc1 | Replication factor C subunit 1. (1159 aa) |
| | wrnip1 | WRN helicase interacting protein 1. (576 aa) |
| | pold1 | DNA polymerase. (1105 aa) |
| | cdt1 | Chromatin licensing and DNA replication factor 1. (459 aa) |
| | ddx11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (854 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (487 aa) |
| | NFIX | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (560 aa) |
| | mgme1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (350 aa) |
| | Dtl | WD_REPEATS_REGION domain-containing protein. (142 aa) |
| | primpol | Primase and polymerase (DNA-directed). (521 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (703 aa) |
| | Gen1 | Chromo_2 domain-containing protein. (523 aa) |
| | LOC107087851 | Ribonucleotide reductase M2 b. (348 aa) |
| | pole3 | Polymerase (DNA directed), epsilon 3 (p17 subunit). (146 aa) |
| | LOC107096926 | Uncharacterized protein. (558 aa) |
| | orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (447 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (373 aa) |
| | Slx4 | BTB domain-containing protein. (1002 aa) |
| | ENSCVAP00000018664 | Uncharacterized protein. (129 aa) |
| | rnaseh2a | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (283 aa) |
| | pold4 | Si:dkey-28b4.7. (107 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1170 aa) |
| | pclaf | PCNA clamp associated factor. (116 aa) |
| | prim2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (505 aa) |
| | tonsl | Tonsoku-like, DNA repair protein. (1433 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (357 aa) |
| | ccne2 | Cyclin E2; Belongs to the cyclin family. (345 aa) |
| | gins3 | GINS complex subunit 3. (211 aa) |
| | polq | Polymerase (DNA directed), theta. (2106 aa) |
| | dscc1 | DNA replication and sister chromatid cohesion 1. (390 aa) |
| | rfwd3 | Ring finger and WD repeat domain 3. (529 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa) |
| | mms22l | MMS22-like, DNA repair protein. (1230 aa) |
| | noc3l | Nucleolar complex protein 3 homolog. (671 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa) |
| | atrx | ATRX chromatin remodeler. (1892 aa) |
| | rnaseh1 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (302 aa) |
| | ddx21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21. (753 aa) |
| | polb | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (339 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (566 aa) |
| | ENSCVAP00000014877 | Uncharacterized protein. (278 aa) |
| | LOC107099910 | BLM RecQ like helicase. (1091 aa) |
| | rmi2 | RecQ mediated genome instability 2. (146 aa) |
| | zpr1 | ZPR1 zinc finger. (170 aa) |
| | chtf8 | CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (131 aa) |
| | prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (425 aa) |
| | ddx23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (802 aa) |
| | orc2 | Origin recognition complex, subunit 2. (536 aa) |
| | fancm | Uncharacterized protein. (1764 aa) |
| | LOC107099458 | Inhibitor of growth family, member 5a. (140 aa) |
| | ssbp1 | Single-stranded DNA binding protein 1. (147 aa) |
| | supt16h | SPT16 homolog, facilitates chromatin remodeling subunit. (1029 aa) |
| | eme1 | Essential meiotic structure-specific endonuclease 1. (522 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (633 aa) |
| | pola1 | DNA polymerase. (1420 aa) |
| | ttc38 | Tetratricopeptide repeat domain 38. (469 aa) |
| | ENSCVAP00000011358 | Uncharacterized protein. (544 aa) |
| | NASP | Nuclear autoantigenic sperm protein. (427 aa) |
| | LOC107088102 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (670 aa) |
| | LOC107089211 | Nuclear autoantigenic sperm protein (histone-binding). (420 aa) |
| | nfia | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (525 aa) |
| | orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (854 aa) |
| | ENSCVAP00000010146 | Tower domain-containing protein. (2271 aa) |
| | rpain | RPA interacting protein. (227 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2017 aa) |
| | cenpx | Centromere protein X. (114 aa) |
| | polk | Polymerase (DNA directed) kappa. (905 aa) |
| | lig1 | DNA ligase. (1004 aa) |
| | chaf1b | Chromatin assembly factor 1, subunit B. (656 aa) |
| | LOC107084294 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (588 aa) |
| | LOC107092444 | Polymerase (DNA-directed), delta 3, accessory subunit. (439 aa) |
| | LOC107087615 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (730 aa) |
| | ENSCVAP00000007749 | CTF/NF-I domain-containing protein. (178 aa) |
| | ticrr | Uncharacterized protein. (1700 aa) |
| | ENSCVAP00000007189 | HD domain-containing protein. (161 aa) |
| | ENSCVAP00000007153 | HD domain-containing protein. (144 aa) |
| | twnk | Twinkle mtDNA helicase. (726 aa) |
| | sde2 | SDE2 telomere maintenance homolog (S. pombe). (406 aa) |
| | ENSCVAP00000005733 | Uncharacterized protein. (144 aa) |
| | ZNF830 | Zinc finger protein 830. (336 aa) |
| | rbm48 | RNA binding motif protein 48. (362 aa) |
| | fbh1 | F-box DNA helicase 1. (882 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (643 aa) |
| | wdhd1 | WD repeat and HMG-box DNA binding protein 1. (1064 aa) |
| | polg | Polymerase (DNA directed), gamma. (1193 aa) |
| | mcmbp | Minichromosome maintenance complex binding protein. (630 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (795 aa) |
| | lig3 | Ligase III, DNA, ATP-dependent. (819 aa) |
| | gins1 | GINS complex subunit 1 (Psf1 homolog). (189 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (814 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (529 aa) |
| | gmnn | Geminin DNA replication inhibitor. (216 aa) |
| | LOC107091169 | ATPase family AAA domain containing 5a. (1526 aa) |
| | mcm10 | Minichromosome maintenance 10 replication initiation factor. (851 aa) |
| | tatdn1 | TatD DNase domain containing 1. (312 aa) |
| | ENSCVAP00000001347 | SCY domain-containing protein. (126 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (738 aa) |
| | timeless | Timeless circadian clock. (1251 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | ENSCVAP00000000721 | Uncharacterized protein. (212 aa) |
| | EME2 | ERCC4 domain-containing protein. (448 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | traip | TRAF-interacting protein. (448 aa) |
| | LOC107100266 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (752 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2502 aa) |
| | orc5 | Origin recognition complex, subunit 5. (442 aa) |
| | sirt7 | Sirtuin 7. (409 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (824 aa) |
| | kin | Kin17 DNA and RNA binding protein. (390 aa) |
| | ssrp1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (707 aa) |
| | orc3 | Origin recognition complex, subunit 3. (679 aa) |
| | thoc1 | THO complex 1. (654 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (388 aa) |
| | LOC107082280 | Uncharacterized protein. (599 aa) |
| | RRM2-2 | Ribonucleotide reductase regulatory subunit M2. (389 aa) |
