(41 nodes) Regulation of glucose metabolic process network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ranbp2	RAN binding protein 2. (3248 aa)
	LOC107082908	Cytochrome c oxidase assembly homolog 11 (yeast). (211 aa)
	ddb1	Damage-specific DNA binding protein 1. (1080 aa)
	fam3c	Family with sequence similarity 3 member C. (227 aa)
	bad	BCL2 associated agonist of cell death b. (163 aa)
	ENSCVAP00000032883	Uncharacterized protein. (111 aa)
	gckr	Uncharacterized protein. (485 aa)
	ogt	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1049 aa)
	lcmt1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	sirt7	Sirtuin 7. (409 aa)
	dusp12	Dual specificity phosphatase 12. (303 aa)
	igf1	Insulin-like growth factor 1. (186 aa)
	pdk1	Protein-serine/threonine kinase. (407 aa)
	pdk4	Protein-serine/threonine kinase. (410 aa)
	midn	Midnolin. (569 aa)
	c1qtnf6	C1q and TNF related 6b. (245 aa)
	mlycd	Malonyl-CoA decarboxylase. (504 aa)
	LOC107093223	Protein-serine/threonine kinase. (404 aa)
	sirt1	Sirtuin 1. (691 aa)
	sirt6	Sirtuin 6. (349 aa)
	lepr	Leptin receptor. (1095 aa)
	LOC107092878	E1A binding protein p300 a. (2648 aa)
	LOC107089487	Insulin-like growth factor 2b. (214 aa)
	ep300	E1A binding protein p300 b. (2766 aa)
	LOC107092305	Uncharacterized protein. (422 aa)
	LOC107087170	C1q and TNF related 6a. (244 aa)
	LOC107091773	Uncharacterized protein. (599 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1182 aa)
	foxk1	Forkhead box K1. (653 aa)
	fam3a	Family with sequence similarity 3 member A. (234 aa)
	LOC107096086	Protein-serine/threonine kinase. (403 aa)
	ENSCVAP00000005569	Protein-serine/threonine kinase. (187 aa)
	DGKQ	Diacylglycerol kinase. (917 aa)
	IGFBP4	Insulin like growth factor binding protein 4. (259 aa)
	Park2	RBR-type E3 ubiquitin transferase. (71 aa)
	ENSCVAP00000007456	Uncharacterized protein. (158 aa)
	gnmt	Glycine N-methyltransferase. (295 aa)
	LOC107089253	Uncharacterized protein. (159 aa)
	soga1	Suppressor of glucose, autophagy associated 1. (1881 aa)
	foxk2	Forkhead box K2. (630 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000032883	igf1	ENSCVAP00000032883	ENSCVAP00000028775	Uncharacterized protein.	Insulin-like growth factor 1.	0.594
IGFBP4	LOC107089487	ENSCVAP00000006418	ENSCVAP00000021048	Insulin like growth factor binding protein 4.	Insulin-like growth factor 2b.	0.699
IGFBP4	igf1	ENSCVAP00000006418	ENSCVAP00000028775	Insulin like growth factor binding protein 4.	Insulin-like growth factor 1.	0.894
LOC107089253	LOC107089487	ENSCVAP00000008615	ENSCVAP00000021048	Uncharacterized protein.	Insulin-like growth factor 2b.	0.474
LOC107089253	igf1	ENSCVAP00000008615	ENSCVAP00000028775	Uncharacterized protein.	Insulin-like growth factor 1.	0.602
LOC107089253	lepr	ENSCVAP00000008615	ENSCVAP00000001749	Uncharacterized protein.	Leptin receptor.	0.874
LOC107089487	IGFBP4	ENSCVAP00000021048	ENSCVAP00000006418	Insulin-like growth factor 2b.	Insulin like growth factor binding protein 4.	0.699
LOC107089487	LOC107089253	ENSCVAP00000021048	ENSCVAP00000008615	Insulin-like growth factor 2b.	Uncharacterized protein.	0.474
LOC107089487	igf1	ENSCVAP00000021048	ENSCVAP00000028775	Insulin-like growth factor 2b.	Insulin-like growth factor 1.	0.751
LOC107091773	ogt	ENSCVAP00000021485	ENSCVAP00000031959	Uncharacterized protein.	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1.	0.697
LOC107092878	ddb1	ENSCVAP00000020689	ENSCVAP00000016510	E1A binding protein p300 a.	Damage-specific DNA binding protein 1.	0.421
LOC107092878	sirt1	ENSCVAP00000020689	ENSCVAP00000004473	E1A binding protein p300 a.	Sirtuin 1.	0.587
ddb1	LOC107092878	ENSCVAP00000016510	ENSCVAP00000020689	Damage-specific DNA binding protein 1.	E1A binding protein p300 a.	0.421
ddb1	ep300	ENSCVAP00000016510	ENSCVAP00000025385	Damage-specific DNA binding protein 1.	E1A binding protein p300 b.	0.421
ddb1	sirt1	ENSCVAP00000016510	ENSCVAP00000004473	Damage-specific DNA binding protein 1.	Sirtuin 1.	0.415
ddb1	sirt6	ENSCVAP00000016510	ENSCVAP00000004309	Damage-specific DNA binding protein 1.	Sirtuin 6.	0.412
ddb1	sirt7	ENSCVAP00000016510	ENSCVAP00000031002	Damage-specific DNA binding protein 1.	Sirtuin 7.	0.594
ddb1	usp7	ENSCVAP00000016510	ENSCVAP00000019034	Damage-specific DNA binding protein 1.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.601
ep300	ddb1	ENSCVAP00000025385	ENSCVAP00000016510	E1A binding protein p300 b.	Damage-specific DNA binding protein 1.	0.421
ep300	sirt1	ENSCVAP00000025385	ENSCVAP00000004473	E1A binding protein p300 b.	Sirtuin 1.	0.587