(62 nodes) Synaptic vesicle exocytosis network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CPLX1	Complexin 2. (133 aa)
	LOC107097210	Synaptotagmin Vb. (424 aa)
	LOC107098345	Otoferlin b. (1632 aa)
	cplx2	Complexin 2. (133 aa)
	LOC107098334	Syntaxin 11a; Belongs to the syntaxin family. (294 aa)
	erc1	ELKS/RAB6-interacting/CAST family member 1a. (1134 aa)
	LOC107085504	Uncharacterized protein. (1474 aa)
	LOC107102522	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (201 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1284 aa)
	STX19	Syntaxin 19. (302 aa)
	LOC107084378	Regulating synaptic membrane exocytosis 3. (324 aa)
	LOC107101860	t-SNARE coiled-coil homology domain-containing protein. (298 aa)
	ENSCVAP00000008755	t-SNARE coiled-coil homology domain-containing protein. (291 aa)
	ENSCVAP00000009295	C2 domain-containing protein. (158 aa)
	LOC107093814	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	LOC107097655	Syntaxin 1B; Belongs to the syntaxin family. (303 aa)
	stx2	Syntaxin 2b; Belongs to the syntaxin family. (268 aa)
	LOC107094896	Synaptotagmin IXb. (525 aa)
	LOC107089162	Uncharacterized protein. (431 aa)
	UNC13C	Unc-13 homolog C. (2108 aa)
	ENSCVAP00000012749	Uncharacterized protein. (133 aa)
	cplx4	Complexin 4a. (159 aa)
	rims1	Regulating synaptic membrane exocytosis 1a. (970 aa)
	snap47	Synaptosome associated protein 47. (425 aa)
	ENSCVAP00000027726	Uncharacterized protein. (188 aa)
	LOC107089917	Complexin 3b. (156 aa)
	ENSCVAP00000024910	Uncharacterized protein. (140 aa)
	fer1l6	Fer-1 like family member 6. (1695 aa)
	ENSCVAP00000024301	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (156 aa)
	syt7	Synaptotagmin VIIb. (563 aa)
	ENSCVAP00000023666	t-SNARE coiled-coil homology domain-containing protein. (289 aa)
	ENSCVAP00000022810	C2 domain-containing protein. (163 aa)
	ENSCVAP00000022246	Synaptotagmin VIIa. (462 aa)
	snap25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (204 aa)
	CADPS2	Calcium dependent secretion activator 2. (1198 aa)
	ENSCVAP00000021350	C2 domain-containing protein. (382 aa)
	LOC107104991	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (555 aa)
	LOC107081396	Otoferlin a. (1849 aa)
	LOC107084483	Uncharacterized protein. (1327 aa)
	ENSCVAP00000018946	Uncharacterized protein. (174 aa)
	cadps	Ca2+-dependent activator protein for secretion b. (1243 aa)
	UNC13B	Unc-13 homolog B. (1438 aa)
	LOC107096951	Unc-13 homolog A. (1603 aa)
	snap29	Synaptosome associated protein 29. (260 aa)
	snapin	SNAP associated protein. (129 aa)
	erc2	ELKS/RAB6-interacting/CAST family member 2. (996 aa)
	LOC107083922	Synaptotagmin IIa. (431 aa)
	stx3	Syntaxin 3A; Belongs to the syntaxin family. (288 aa)
	LOC107084039	Synaptotagmin IXa. (563 aa)
	syt12	Synaptotagmin XII. (423 aa)
	syt1	Synaptotagmin Ia. (422 aa)
	ENSCVAP00000028571	Proline-rich transmembrane protein 2. (166 aa)
	LOC107102333	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (285 aa)
	LOC107101223	Synaptotagmin-1-like. (424 aa)
	ENSCVAP00000027927	Uncharacterized protein. (290 aa)
	LOC107093748	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (233 aa)
	ENSCVAP00000000394	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (231 aa)
	LOC107094597	FIP-RBD domain-containing protein. (952 aa)
	LOC107095723	Uncharacterized protein. (1189 aa)
	LOC107081878	Syntaxin 1A (brain); Belongs to the syntaxin family. (287 aa)
	ENSCVAP00000003610	Uncharacterized protein. (73 aa)
	LOC107098387	Uncharacterized protein. (1525 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPLX1	ENSCVAP00000000394	ENSCVAP00000015574	ENSCVAP00000000394	Complexin 2.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.409
CPLX1	ENSCVAP00000024301	ENSCVAP00000015574	ENSCVAP00000024301	Complexin 2.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.409
CPLX1	LOC107102522	ENSCVAP00000015574	ENSCVAP00000007611	Complexin 2.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.409
CPLX1	snap25	ENSCVAP00000015574	ENSCVAP00000021761	Complexin 2.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.409
ENSCVAP00000000394	CPLX1	ENSCVAP00000000394	ENSCVAP00000015574	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Complexin 2.	0.409
ENSCVAP00000000394	ENSCVAP00000003610	ENSCVAP00000000394	ENSCVAP00000003610	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Uncharacterized protein.	0.408
ENSCVAP00000000394	ENSCVAP00000008755	ENSCVAP00000000394	ENSCVAP00000008755	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	t-SNARE coiled-coil homology domain-containing protein.	0.692
ENSCVAP00000000394	ENSCVAP00000009295	ENSCVAP00000000394	ENSCVAP00000009295	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	C2 domain-containing protein.	0.737
ENSCVAP00000000394	ENSCVAP00000021350	ENSCVAP00000000394	ENSCVAP00000021350	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	C2 domain-containing protein.	0.501
ENSCVAP00000000394	ENSCVAP00000022246	ENSCVAP00000000394	ENSCVAP00000022246	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Synaptotagmin VIIa.	0.408
ENSCVAP00000000394	ENSCVAP00000022810	ENSCVAP00000000394	ENSCVAP00000022810	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	C2 domain-containing protein.	0.737
ENSCVAP00000000394	ENSCVAP00000023666	ENSCVAP00000000394	ENSCVAP00000023666	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	t-SNARE coiled-coil homology domain-containing protein.	0.692
ENSCVAP00000000394	LOC107081878	ENSCVAP00000000394	ENSCVAP00000003246	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Syntaxin 1A (brain); Belongs to the syntaxin family.	0.775
ENSCVAP00000000394	LOC107083922	ENSCVAP00000000394	ENSCVAP00000032835	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Synaptotagmin IIa.	0.817
ENSCVAP00000000394	LOC107084378	ENSCVAP00000000394	ENSCVAP00000008496	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Regulating synaptic membrane exocytosis 3.	0.509
ENSCVAP00000000394	LOC107084483	ENSCVAP00000000394	ENSCVAP00000019759	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Uncharacterized protein.	0.697
ENSCVAP00000000394	LOC107085504	ENSCVAP00000000394	ENSCVAP00000006549	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Uncharacterized protein.	0.509
ENSCVAP00000000394	LOC107089162	ENSCVAP00000000394	ENSCVAP00000012682	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Uncharacterized protein.	0.817
ENSCVAP00000000394	LOC107093814	ENSCVAP00000000394	ENSCVAP00000009964	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Syntaxin 4; Belongs to the syntaxin family.	0.736
ENSCVAP00000000394	LOC107095723	ENSCVAP00000000394	ENSCVAP00000002263	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Uncharacterized protein.	0.501