(101 nodes) Histone methylation network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fbl	Fibrillarin. (315 aa)
	wdr82	WD repeat domain 82. (313 aa)
	LOC107086058	Lysine methyltransferase 5Aa. (411 aa)
	ezh2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (761 aa)
	ENSCVAP00000005869	Uncharacterized protein. (258 aa)
	ENSCVAP00000006795	Uncharacterized protein. (334 aa)
	dpy30	Dpy-30 histone methyltransferase complex regulatory subunit. (105 aa)
	LOC107103115	WD_REPEATS_REGION domain-containing protein. (315 aa)
	LOC107085982	Protein arginine methyltransferase 8b; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (405 aa)
	ncoa6	Nuclear receptor coactivator 6. (2394 aa)
	pno1	Partner of NOB1 homolog. (248 aa)
	wdr61	WD repeat domain 61. (300 aa)
	LOC107092173	SET and MYND domain containing 2a. (435 aa)
	suv39h1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (405 aa)
	setd1a	SET domain containing 1A, histone lysine methyltransferase. (2177 aa)
	mettl23	Methyltransferase like 23. (248 aa)
	Znf335	Uncharacterized protein. (859 aa)
	ZNF335	Zinc finger protein 335. (674 aa)
	nfya	Nuclear transcription factor Y, alpha, like. (344 aa)
	pwp1	PWP1 homolog, endonuclein. (551 aa)
	n6amt1	N-6 adenine-specific DNA methyltransferase 1. (226 aa)
	ENSCVAP00000013077	SET domain-containing protein. (176 aa)
	rbbp5	Retinoblastoma binding protein 5. (473 aa)
	LOC107096940	SET domain-containing protein. (1939 aa)
	dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1365 aa)
	nsd3	Nuclear receptor binding SET domain protein 3. (1600 aa)
	ENSCVAP00000014960	BRCT domain-containing protein. (175 aa)
	prmt7	Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (685 aa)
	LOC107084057	Ash1 (absent, small, or homeotic)-like (Drosophila). (2925 aa)
	LOC107101862	Nuclear receptor binding SET domain protein 1a. (2130 aa)
	PRDM6	PR/SET domain 6. (592 aa)
	mecom	MDS1 and EVI1 complex locus. (1306 aa)
	prdm1	PR domain containing 1a, with ZNF domain. (844 aa)
	ash2l	Ash2 like, histone lysine methyltransferase complex subunit. (593 aa)
	LOC107086273	SET and MYND domain containing 1b. (489 aa)
	kiaa2013	Si:dkeyp-104h9.5. (620 aa)
	ENSCVAP00000018590	Uncharacterized protein. (362 aa)
	Kmt2d	Uncharacterized protein. (406 aa)
	LOC107098659	Euchromatic histone-lysine N-methyltransferase 1a. (770 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	prmt5	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (653 aa)
	nsd2	Nuclear receptor binding SET domain protein 2. (1456 aa)
	nsd1	Nuclear receptor binding SET domain protein 1b. (2513 aa)
	LOC107100318	Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (439 aa)
	crebbp	CREB binding protein b. (2380 aa)
	ENSCVAP00000002405	SET domain-containing protein. (177 aa)
	arid4b	Translocase of outer mitochondrial membrane 20. (1290 aa)
	ehmt2	Euchromatic histone-lysine N-methyltransferase 2. (1130 aa)
	prmt6	Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (351 aa)
	ENSCVAP00000001057	Nuclear receptor domain-containing protein. (91 aa)
	LOC107081272	Uncharacterized protein. (781 aa)
	prdm13	PR domain containing 13. (625 aa)
	LOC107091290	SET domain containing 1B, histone lysine methyltransferase a. (1782 aa)
	smyd2	Uncharacterized protein. (432 aa)
	LOC107083428	CREB binding protein a. (2444 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (768 aa)
	Kmt2c	Uncharacterized protein. (464 aa)
	LOC107087301	Lysine methyltransferase 5Ab. (345 aa)
	prdm14	PR domain containing 14. (576 aa)
	cxxc1	CXXC finger protein 1b. (561 aa)
	LOC107099240	Methyl CpG binding protein 2. (937 aa)
	LOC107099357	CXXC finger protein 1a. (478 aa)
	ENSCVAP00000020558	Nuclear receptor domain-containing protein. (109 aa)
	LOC107099179	Uncharacterized protein. (587 aa)
	kmt2b	Lysine (K)-specific methyltransferase 2Bb. (3841 aa)
	prdm16	Si:ch211-263k4.2. (1374 aa)
	KMT2A	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4453 aa)
	nfyc	Nuclear transcription factor Y, gamma. (355 aa)
	Arid4a	Tudor domain-containing protein. (327 aa)
	setdb1	SET domain bifurcated histone lysine methyltransferase 1b. (1250 aa)
	gcc1	GRIP and coiled-coil domain containing 1. (762 aa)
	carm1	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (600 aa)
	ehmt1	Euchromatic histone-lysine N-methyltransferase 1b. (1279 aa)
	SMYD3	SET and MYND domain containing 3. (453 aa)
	setd2	SET domain containing 2, histone lysine methyltransferase. (2591 aa)
	setbp1	SET binding protein 1. (1502 aa)
	ntmt1	N-terminal Xaa-Pro-Lys N-methyltransferase 1. (222 aa)
	prdm5	Zinc finger protein. (611 aa)
	prmt1	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (366 aa)
	setd3	Protein-histidine N-methyltransferase. (609 aa)
	ENSCVAP00000027617	Uncharacterized protein. (138 aa)
	ENSCVAP00000027729	Multiple endocrine neoplasia I. (444 aa)
	eed	Embryonic ectoderm development. (443 aa)
	pagr1	PAXIP1 associated glutamate-rich protein 1. (277 aa)
	wdr5	WD repeat domain 5. (333 aa)
	LOC107094245	PR domain containing 1b, with ZNF domain. (709 aa)
	ctr9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1146 aa)
	setd4	Uncharacterized protein. (454 aa)
	setd5	SET domain containing 5. (1435 aa)
	LOC107101115	Lysine (K)-specific methyltransferase 2Ba. (2574 aa)
	prmt2	Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (415 aa)
	LOC107082340	SET domain and mariner transposase fusion gene. (283 aa)
	smyd5	SMYD family member 5. (438 aa)
	sirt7	Sirtuin 7. (409 aa)
	ogt	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1049 aa)
	rtf1	RTF1 homolog, Paf1/RNA polymerase II complex component. (677 aa)
	ENSCVAP00000032487	Uncharacterized protein. (153 aa)
	kmt5b	Lysine methyltransferase 5B. (855 aa)
	setd7	SET domain containing 7, histone lysine methyltransferase. (382 aa)
	ENSCVAP00000032726	Uncharacterized protein. (336 aa)
	bend3	BEN domain containing 3. (801 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arid4a	ENSCVAP00000032487	ENSCVAP00000024072	ENSCVAP00000032487	Tudor domain-containing protein.	Uncharacterized protein.	0.569
Arid4a	EZH1	ENSCVAP00000024072	ENSCVAP00000019320	Tudor domain-containing protein.	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.425
Arid4a	LOC107084057	ENSCVAP00000024072	ENSCVAP00000015123	Tudor domain-containing protein.	Ash1 (absent, small, or homeotic)-like (Drosophila).	0.569
Arid4a	LOC107091290	ENSCVAP00000024072	ENSCVAP00000018734	Tudor domain-containing protein.	SET domain containing 1B, histone lysine methyltransferase a.	0.527
Arid4a	LOC107099240	ENSCVAP00000024072	ENSCVAP00000020494	Tudor domain-containing protein.	Methyl CpG binding protein 2.	0.650
Arid4a	LOC107099357	ENSCVAP00000024072	ENSCVAP00000020544	Tudor domain-containing protein.	CXXC finger protein 1a.	0.464
Arid4a	LOC107101862	ENSCVAP00000024072	ENSCVAP00000015246	Tudor domain-containing protein.	Nuclear receptor binding SET domain protein 1a.	0.403
Arid4a	arid4b	ENSCVAP00000024072	ENSCVAP00000002162	Tudor domain-containing protein.	Translocase of outer mitochondrial membrane 20.	0.615
Arid4a	cxxc1	ENSCVAP00000024072	ENSCVAP00000020046	Tudor domain-containing protein.	CXXC finger protein 1b.	0.464
Arid4a	ezh2	ENSCVAP00000024072	ENSCVAP00000005808	Tudor domain-containing protein.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.425
Arid4a	nsd1	ENSCVAP00000024072	ENSCVAP00000003886	Tudor domain-containing protein.	Nuclear receptor binding SET domain protein 1b.	0.403
Arid4a	nsd2	ENSCVAP00000024072	ENSCVAP00000003908	Tudor domain-containing protein.	Nuclear receptor binding SET domain protein 2.	0.403
Arid4a	nsd3	ENSCVAP00000024072	ENSCVAP00000014957	Tudor domain-containing protein.	Nuclear receptor binding SET domain protein 3.	0.403
Arid4a	setbp1	ENSCVAP00000024072	ENSCVAP00000027131	Tudor domain-containing protein.	SET binding protein 1.	0.569
Arid4a	setd1a	ENSCVAP00000024072	ENSCVAP00000009670	Tudor domain-containing protein.	SET domain containing 1A, histone lysine methyltransferase.	0.527
Arid4a	setd2	ENSCVAP00000024072	ENSCVAP00000025912	Tudor domain-containing protein.	SET domain containing 2, histone lysine methyltransferase.	0.645
Arid4a	setd7	ENSCVAP00000024072	ENSCVAP00000032697	Tudor domain-containing protein.	SET domain containing 7, histone lysine methyltransferase.	0.425
ENSCVAP00000001057	LOC107083428	ENSCVAP00000001057	ENSCVAP00000019004	Nuclear receptor domain-containing protein.	CREB binding protein a.	0.452
ENSCVAP00000001057	carm1	ENSCVAP00000001057	ENSCVAP00000025277	Nuclear receptor domain-containing protein.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.466
ENSCVAP00000001057	crebbp	ENSCVAP00000001057	ENSCVAP00000002467	Nuclear receptor domain-containing protein.	CREB binding protein b.	0.452