(37 nodes) Lipid storage network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	angptl3	Angiopoietin-like 3. (468 aa)
	ldah	Lipid droplet associated hydrolase. (336 aa)
	LOC107097085	Uncharacterized protein. (725 aa)
	LOC107083616	Fibrinogen C-terminal domain-containing protein. (473 aa)
	LOC107102418	PLA2c domain-containing protein. (452 aa)
	LOC107082966	G_PROTEIN_RECEP_F1_2 domain-containing protein. (345 aa)
	tmem159	Uncharacterized protein. (148 aa)
	LOC107083994	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (458 aa)
	zfyve1	Zinc finger, FYVE domain containing 1. (774 aa)
	LOC107086793	Beta-1,4 N-acetylgalactosaminyltransferase. (531 aa)
	LOC107099476	Interleukin-1. (247 aa)
	bscl2	Uncharacterized protein. (389 aa)
	gm2a	GM2 ganglioside activator. (199 aa)
	smim22	Uncharacterized protein. (72 aa)
	fitm2	Fat storage inducing transmembrane protein 2. (253 aa)
	LOC107092186	PNPLA domain-containing protein. (334 aa)
	hexb	Beta-hexosaminidase. (546 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	ZFYVE1	Uncharacterized protein. (621 aa)
	LOC107094496	Si:ch211-11n16.2. (655 aa)
	fitm1	Fat storage inducing transmembrane protein 1. (319 aa)
	LOC107098564	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (450 aa)
	b4galnt1	Beta-1,4 N-acetylgalactosaminyltransferase. (531 aa)
	ENSCVAP00000017074	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (64 aa)
	hexa	Beta-hexosaminidase. (535 aa)
	LOC107088608	Fat storage inducing transmembrane protein 1, like. (284 aa)
	ENSCVAP00000014655	CIDE-N domain-containing protein. (181 aa)
	ENSCVAP00000014541	Si:dkey-211g8.6. (316 aa)
	LOC107101198	PNPLA domain-containing protein. (439 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (415 aa)
	LOC107101622	Patatin-like phospholipase domain containing 3. (469 aa)
	nrip1	Nuclear receptor interacting protein 1b. (1195 aa)
	sqle	Squalene epoxidase a. (570 aa)
	LOC107093336	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
	cd36	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (468 aa)
	ENSCVAP00000021159	Uncharacterized protein. (260 aa)
	ENSCVAP00000021265	BSCL2 lipid droplet biogenesis associated, seipin. (334 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000014655	LOC107101198	ENSCVAP00000014655	ENSCVAP00000012670	CIDE-N domain-containing protein.	PNPLA domain-containing protein.	0.400
ENSCVAP00000014655	LOC107101622	ENSCVAP00000014655	ENSCVAP00000018088	CIDE-N domain-containing protein.	Patatin-like phospholipase domain containing 3.	0.408
ENSCVAP00000017074	LOC107099476	ENSCVAP00000017074	ENSCVAP00000011289	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Interleukin-1.	0.862
ENSCVAP00000017074	cd36	ENSCVAP00000017074	ENSCVAP00000020091	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family.	0.430
ENSCVAP00000021265	tmem159	ENSCVAP00000021265	ENSCVAP00000030319	BSCL2 lipid droplet biogenesis associated, seipin.	Uncharacterized protein.	0.446
LOC107083994	LOC107098564	ENSCVAP00000031611	ENSCVAP00000001247	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	0.901
LOC107083994	aup1	ENSCVAP00000031611	ENSCVAP00000017827	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	AUP1 lipid droplet regulating VLDL assembly factor.	0.412
LOC107086793	b4galnt1	ENSCVAP00000032191	ENSCVAP00000000396	Beta-1,4 N-acetylgalactosaminyltransferase.	Beta-1,4 N-acetylgalactosaminyltransferase.	0.901
LOC107086793	hexa	ENSCVAP00000032191	ENSCVAP00000016210	Beta-1,4 N-acetylgalactosaminyltransferase.	Beta-hexosaminidase.	0.916
LOC107086793	hexb	ENSCVAP00000032191	ENSCVAP00000008309	Beta-1,4 N-acetylgalactosaminyltransferase.	Beta-hexosaminidase.	0.916
LOC107092186	LOC107101198	ENSCVAP00000025082	ENSCVAP00000012670	PNPLA domain-containing protein.	PNPLA domain-containing protein.	0.909
LOC107092186	LOC107101622	ENSCVAP00000025082	ENSCVAP00000018088	PNPLA domain-containing protein.	Patatin-like phospholipase domain containing 3.	0.904
LOC107098564	LOC107083994	ENSCVAP00000001247	ENSCVAP00000031611	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	0.901
LOC107098564	aup1	ENSCVAP00000001247	ENSCVAP00000017827	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	AUP1 lipid droplet regulating VLDL assembly factor.	0.412
LOC107099476	ENSCVAP00000017074	ENSCVAP00000011289	ENSCVAP00000017074	Interleukin-1.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.862
LOC107099476	cd36	ENSCVAP00000011289	ENSCVAP00000020091	Interleukin-1.	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family.	0.415
LOC107101198	ENSCVAP00000014655	ENSCVAP00000012670	ENSCVAP00000014655	PNPLA domain-containing protein.	CIDE-N domain-containing protein.	0.400
LOC107101198	LOC107092186	ENSCVAP00000012670	ENSCVAP00000025082	PNPLA domain-containing protein.	PNPLA domain-containing protein.	0.909
LOC107101198	LOC107101622	ENSCVAP00000012670	ENSCVAP00000018088	PNPLA domain-containing protein.	Patatin-like phospholipase domain containing 3.	0.907
LOC107101622	ENSCVAP00000014655	ENSCVAP00000018088	ENSCVAP00000014655	Patatin-like phospholipase domain containing 3.	CIDE-N domain-containing protein.	0.408