55 items (Cyprinodon variegatus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	atp6ap1	ATPase H+ transporting accessory protein 1a. (484 aa)
	LOC107083338	Si:dkey-206f10.1. (1094 aa)
	ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
	cltcl1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1690 aa)
	synrg	Synergin, gamma. (1452 aa)
	LOC107104603	Uncharacterized protein. (617 aa)
	LOC107082456	Epsin 3b. (601 aa)
	LOC107092991	Receptor expression-enhancing protein. (184 aa)
	LOC107101194	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
	LOC107090293	AP complex subunit beta. (919 aa)
	epn2	Epsin 2. (579 aa)
	atp6ap2	ATPase H+ transporting accessory protein 2. (362 aa)
	ap1b1	AP complex subunit beta. (985 aa)
	LOC107089200	Receptor expression-enhancing protein. (244 aa)
	adcy8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1048 aa)
	ENSCVAP00000025427	Uncharacterized protein. (249 aa)
	LOC107101887	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
	atp6v1h	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (484 aa)
	atp6v1f	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	LOC107101473	Alpha_adaptinC2 domain-containing protein. (841 aa)
	ap1g1	AP-1 complex subunit gamma. (820 aa)
	LOC107103921	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (948 aa)
	ENSCVAP00000020208	Adaptin_N domain-containing protein. (158 aa)
	LOC107093198	Adaptin_N domain-containing protein. (554 aa)
	LOC107082258	DUF1681 domain-containing protein. (252 aa)
	atp6v0b	ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
	aftph	Aftiphilin a. (734 aa)
	LOC107085658	NECAP endocytosis associated 2. (255 aa)
	LOC107089004	NECAP endocytosis associated 1. (263 aa)
	ENSCVAP00000018854	ENTH domain-containing protein. (92 aa)
	ENSCVAP00000018109	DENN/MADD domain containing 1A. (184 aa)
	ENSCVAP00000017720	Uncharacterized protein. (417 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
	ENSCVAP00000014430	Uncharacterized protein. (114 aa)
	LOC107104663	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	ENSCVAP00000012583	Uncharacterized protein. (58 aa)
	ENSCVAP00000012437	Solute carrier family 18 member 3a. (515 aa)
	cltb	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (197 aa)
	LOC107084222	ENTH domain-containing protein. (671 aa)
	ap3b1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1122 aa)
	ENSCVAP00000010568	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (391 aa)
	LOC107086539	Clathrin interactor 1a. (615 aa)
	dct	Dopachrome tautomerase. (525 aa)
	LOC107100152	Epsin 3a. (601 aa)
	LOC107089997	Solute carrier family 18 member A3. (518 aa)
	LOC107087706	AP-1 complex subunit gamma. (798 aa)
	atp6v1a	ATPase H+ transporting V1 subunit A. (617 aa)
	LOC107102059	ATPase H+ transporting accessory protein 1b. (400 aa)
	atp6v1d	ATPase H+ transporting V1 subunit D. (248 aa)
	tyrp1	Tyrosinase related protein 1. (525 aa)
	LOC107095751	Uncharacterized protein. (102 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
	LOC107082218	Epsin 1. (644 aa)
	dab2	DAB adaptor protein 2. (767 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0C	LOC107101194	ENSCVAP00000000603	ENSCVAP00000028900	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.900
ATP6V0C	LOC107102059	ENSCVAP00000000603	ENSCVAP00000003183	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 1b.	0.920
ATP6V0C	LOC107103921	ENSCVAP00000000603	ENSCVAP00000021034	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.484
ATP6V0C	LOC107104603	ENSCVAP00000000603	ENSCVAP00000030053	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.965
ATP6V0C	ap2m1	ENSCVAP00000000603	ENSCVAP00000031359	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.734
ATP6V0C	atp6ap1	ENSCVAP00000000603	ENSCVAP00000005593	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 1a.	0.920
ATP6V0C	atp6ap2	ENSCVAP00000000603	ENSCVAP00000027961	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 2.	0.927
ATP6V0C	atp6v0b	ENSCVAP00000000603	ENSCVAP00000019834	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family.	0.999
ATP6V0C	atp6v1a	ENSCVAP00000000603	ENSCVAP00000004193	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting V1 subunit A.	0.965
ATP6V0C	atp6v1d	ENSCVAP00000000603	ENSCVAP00000002343	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting V1 subunit D.	0.985
ATP6V0C	atp6v1f	ENSCVAP00000000603	ENSCVAP00000023747	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.989
ATP6V0C	atp6v1h	ENSCVAP00000000603	ENSCVAP00000024498	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.984
ENSCVAP00000012437	LOC107101473	ENSCVAP00000012437	ENSCVAP00000023523	Solute carrier family 18 member 3a.	Alpha_adaptinC2 domain-containing protein.	0.496
ENSCVAP00000012583	ENSCVAP00000014430	ENSCVAP00000012583	ENSCVAP00000014430	Uncharacterized protein.	Uncharacterized protein.	0.780
ENSCVAP00000012583	ENSCVAP00000018854	ENSCVAP00000012583	ENSCVAP00000018854	Uncharacterized protein.	ENTH domain-containing protein.	0.567
ENSCVAP00000012583	ENSCVAP00000020208	ENSCVAP00000012583	ENSCVAP00000020208	Uncharacterized protein.	Adaptin_N domain-containing protein.	0.514
ENSCVAP00000012583	LOC107082218	ENSCVAP00000012583	ENSCVAP00000000330	Uncharacterized protein.	Epsin 1.	0.600
ENSCVAP00000012583	LOC107082258	ENSCVAP00000012583	ENSCVAP00000020075	Uncharacterized protein.	DUF1681 domain-containing protein.	0.700
ENSCVAP00000012583	LOC107082456	ENSCVAP00000012583	ENSCVAP00000029431	Uncharacterized protein.	Epsin 3b.	0.600
ENSCVAP00000012583	LOC107084222	ENSCVAP00000012583	ENSCVAP00000011420	Uncharacterized protein.	ENTH domain-containing protein.	0.463