50 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107102199	G_PROTEIN_RECEP_F1_2 domain-containing protein. (367 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (323 aa)
	LOC107101644	S-antigen; retina and pineal gland (arrestin) a. (398 aa)
	arrb1	Arrestin, beta 1. (416 aa)
	LOC107083423	Calcyon neuron-specific vesicular protein. (198 aa)
	ENSCVAP00000032602	Receptor (G protein-coupled) activity modifying protein 2. (213 aa)
	ENSCVAP00000005988	Uncharacterized protein. (53 aa)
	LOC107101485	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (858 aa)
	ENSCVAP00000004058	Uncharacterized protein. (80 aa)
	LOC107100306	Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (341 aa)
	RAMP3	Receptor activity modifying protein 3. (118 aa)
	LOC107093407	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
	ramp1	Receptor activity modifying protein 1. (150 aa)
	LOC107089007	Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (373 aa)
	cacng3	Calcium voltage-gated channel auxiliary subunit gamma 3. (317 aa)
	ENSCVAP00000019075	Uncharacterized protein. (79 aa)
	LOC107093348	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC107093336	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
	LOC107082163	Calcium channel, voltage-dependent, gamma subunit 8b. (413 aa)
	arr3	Arrestin 3. (367 aa)
	dnm3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (825 aa)
	ackr3	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	tspan8	CD9 molecule b; Belongs to the tetraspanin (TM4SF) family. (212 aa)
	arrb2	Arrestin, beta 2a. (407 aa)
	LOC107101887	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
	LOC107102394	Tetraspanin. (228 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (465 aa)
	RAMP1	Receptor activity modifying protein 1. (153 aa)
	LOC107083642	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (795 aa)
	cacng4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (333 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (525 aa)
	cltcl1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1690 aa)
	LOC107092533	Calcium channel, voltage-dependent, gamma subunit 5b. (276 aa)
	lmbrd1	LMBR1 domain containing 1. (494 aa)
	LOC107088996	Calcium channel, voltage-dependent, gamma subunit 8a. (450 aa)
	LOC107105219	Contactin 2. (640 aa)
	LOC107093644	Low density lipoprotein receptor adaptor protein 1a. (307 aa)
	dnm1	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
	ENSCVAP00000014430	Uncharacterized protein. (114 aa)
	LOC107103482	S-antigen; retina and pineal gland (arrestin) b. (387 aa)
	LOC107104663	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	LOC107084194	Arrestin 3a, retinal (X-arrestin). (355 aa)
	LOC107104264	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (797 aa)
	cacng5	Calcium channel, voltage-dependent, gamma subunit 5a. (277 aa)
	scyl2	SCY1 like pseudokinase 2. (922 aa)
	LOC107101843	Uncharacterized protein. (205 aa)
	cacng2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (317 aa)
	LOC107102522	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (201 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (772 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000014430	LOC107083642	ENSCVAP00000014430	ENSCVAP00000027467	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.538
ENSCVAP00000014430	LOC107084194	ENSCVAP00000014430	ENSCVAP00000012182	Uncharacterized protein.	Arrestin 3a, retinal (X-arrestin).	0.704
ENSCVAP00000014430	LOC107093407	ENSCVAP00000014430	ENSCVAP00000000088	Uncharacterized protein.	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.538
ENSCVAP00000014430	LOC107093644	ENSCVAP00000014430	ENSCVAP00000015162	Uncharacterized protein.	Low density lipoprotein receptor adaptor protein 1a.	0.461
ENSCVAP00000014430	LOC107101485	ENSCVAP00000014430	ENSCVAP00000005359	Uncharacterized protein.	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.538
ENSCVAP00000014430	LOC107101644	ENSCVAP00000014430	ENSCVAP00000017780	Uncharacterized protein.	S-antigen; retina and pineal gland (arrestin) a.	0.704
ENSCVAP00000014430	LOC107103482	ENSCVAP00000014430	ENSCVAP00000014397	Uncharacterized protein.	S-antigen; retina and pineal gland (arrestin) b.	0.704
ENSCVAP00000014430	LOC107104264	ENSCVAP00000014430	ENSCVAP00000012157	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.538
ENSCVAP00000014430	arr3	ENSCVAP00000014430	ENSCVAP00000020315	Uncharacterized protein.	Arrestin 3.	0.701
ENSCVAP00000014430	arrb1	ENSCVAP00000014430	ENSCVAP00000018099	Uncharacterized protein.	Arrestin, beta 1.	0.704
ENSCVAP00000014430	arrb2	ENSCVAP00000014430	ENSCVAP00000025182	Uncharacterized protein.	Arrestin, beta 2a.	0.704
ENSCVAP00000014430	dnm1	ENSCVAP00000014430	ENSCVAP00000014698	Uncharacterized protein.	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.538
ENSCVAP00000014430	dnm3	ENSCVAP00000014430	ENSCVAP00000021698	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.538
ENSCVAP00000014430	hgs	ENSCVAP00000014430	ENSCVAP00000007114	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.823
ENSCVAP00000014430	ldlrap1	ENSCVAP00000014430	ENSCVAP00000016700	Uncharacterized protein.	Low density lipoprotein receptor adaptor protein 1b.	0.519
ENSCVAP00000019075	ENSCVAP00000032602	ENSCVAP00000019075	ENSCVAP00000032602	Uncharacterized protein.	Receptor (G protein-coupled) activity modifying protein 2.	0.482
ENSCVAP00000019075	LOC107101843	ENSCVAP00000019075	ENSCVAP00000009749	Uncharacterized protein.	Uncharacterized protein.	0.482
ENSCVAP00000019075	RAMP3	ENSCVAP00000019075	ENSCVAP00000002167	Uncharacterized protein.	Receptor activity modifying protein 3.	0.496
ENSCVAP00000032602	ENSCVAP00000019075	ENSCVAP00000032602	ENSCVAP00000019075	Receptor (G protein-coupled) activity modifying protein 2.	Uncharacterized protein.	0.482
ENSCVAP00000032602	RAMP1	ENSCVAP00000032602	ENSCVAP00000026598	Receptor (G protein-coupled) activity modifying protein 2.	Receptor activity modifying protein 1.	0.482