(62 nodes) Regulation of peptidyl-serine phosphorylation network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107101862	Nuclear receptor binding SET domain protein 1a. (2130 aa)
	hax1	HCLS1 associated protein X-1. (304 aa)
	ENSCVAP00000017074	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (64 aa)
	LOC107086285	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (179 aa)
	paqr3	Progestin and adipoQ receptor family member IIIa. (343 aa)
	LOC107087273	Inositol polyphosphate-5-phosphatase Jb. (531 aa)
	LOC107083382	BCL2 apoptosis regulator b. (227 aa)
	LOC107093336	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
	fnip1	Folliculin interacting protein 1. (1230 aa)
	LOC107092680	Inositol polyphosphate-5-phosphatase Ja. (396 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC107092889	Uncharacterized protein. (180 aa)
	epm2a	EPM2A glucan phosphatase, laforin. (320 aa)
	SMYD3	SET and MYND domain containing 3. (453 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (613 aa)
	LOC107101801	SH2 domain containing 3A. (744 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (491 aa)
	stox1	Storkhead box 1. (1096 aa)
	ENSCVAP00000027713	Teneurin N-terminal domain-containing protein. (170 aa)
	LOC107090307	Sprouty RTK signaling antagonist 2. (351 aa)
	LOC107090891	Protein phosphatase 1, regulatory subunit 15B. (554 aa)
	LOC107101723	Uncharacterized protein. (1699 aa)
	ENSCVAP00000028612	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	ucn	Urotensin 1. (144 aa)
	dkk1	Dickkopf WNT signaling pathway inhibitor 1a. (261 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (460 aa)
	ENSCVAP00000000311	Interleukin 11a. (199 aa)
	ENSCVAP00000000995	Uncharacterized protein. (175 aa)
	RAMP3	Receptor activity modifying protein 3. (118 aa)
	ercc6	Excision repair cross-complementation group 6. (1441 aa)
	bag4	BCL2 associated athanogene 4. (372 aa)
	nck2	Cytoplasmic protein. (395 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1724 aa)
	nsd1	Nuclear receptor binding SET domain protein 1b. (2513 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
	LOC107097204	Uncharacterized protein. (317 aa)
	LOC107089369	Inositol polyphosphate-5-phosphatase Kb. (323 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1373 aa)
	pink1	PTEN induced kinase 1. (472 aa)
	ntf3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (302 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	ENSCVAP00000007327	Uncharacterized protein. (49 aa)
	gas6	Uncharacterized protein. (652 aa)
	LOC107087023	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (287 aa)
	LOC107103699	Transforming growth factor beta; Belongs to the TGF-beta family. (349 aa)
	LOC107096601	Uncharacterized protein. (837 aa)
	sh2d3c	SH2 domain containing 3Ca. (861 aa)
	ENSCVAP00000011304	Uncharacterized protein. (147 aa)
	ENSCVAP00000011876	Uncharacterized protein. (457 aa)
	LOC107103532	MAPK associated protein 1. (486 aa)
	pwp1	PWP1 homolog, endonuclein. (551 aa)
	LOC107091899	Rap guanine nucleotide exchange factor (GEF) 3. (868 aa)
	LOC107092016	Progestin and adipoQ receptor family member IIIb. (313 aa)
	LOC107097242	NGF domain-containing protein; Belongs to the NGF-beta family. (419 aa)
	mad2l2	Mitotic arrest deficient 2 like 2. (210 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	BDKRB2	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	nck1	Cytoplasmic protein. (394 aa)
	LOC107101163	BCAR3 adaptor protein, NSP family member. (954 aa)
	LOC107091926	Uncharacterized protein. (339 aa)
	LOC107080667	Uncharacterized protein. (202 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	ENSCVAP00000011304	ENSCVAP00000027282	ENSCVAP00000011304	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.874
BAX	LOC107080667	ENSCVAP00000027282	ENSCVAP00000015020	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.992
BAX	LOC107083382	ENSCVAP00000027282	ENSCVAP00000019531	BCL2 associated X, apoptosis regulator.	BCL2 apoptosis regulator b.	0.992
ENSCVAP00000000995	LOC107092889	ENSCVAP00000000995	ENSCVAP00000023869	Uncharacterized protein.	Uncharacterized protein.	0.654
ENSCVAP00000000995	LOC107097242	ENSCVAP00000000995	ENSCVAP00000013066	Uncharacterized protein.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.404
ENSCVAP00000011304	BAX	ENSCVAP00000011304	ENSCVAP00000027282	Uncharacterized protein.	BCL2 associated X, apoptosis regulator.	0.874
ENSCVAP00000011304	LOC107080667	ENSCVAP00000011304	ENSCVAP00000015020	Uncharacterized protein.	Uncharacterized protein.	0.736
ENSCVAP00000011304	LOC107083382	ENSCVAP00000011304	ENSCVAP00000019531	Uncharacterized protein.	BCL2 apoptosis regulator b.	0.736
ENSCVAP00000011876	ENSCVAP00000027713	ENSCVAP00000011876	ENSCVAP00000027713	Uncharacterized protein.	Teneurin N-terminal domain-containing protein.	0.836
ENSCVAP00000011876	LOC107101723	ENSCVAP00000011876	ENSCVAP00000028466	Uncharacterized protein.	Uncharacterized protein.	0.776
ENSCVAP00000017074	LOC107080667	ENSCVAP00000017074	ENSCVAP00000015020	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.423
ENSCVAP00000017074	LOC107083382	ENSCVAP00000017074	ENSCVAP00000019531	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	BCL2 apoptosis regulator b.	0.423
ENSCVAP00000017074	LOC107103699	ENSCVAP00000017074	ENSCVAP00000008432	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.642
ENSCVAP00000017074	RIPK2	ENSCVAP00000017074	ENSCVAP00000030122	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Receptor interacting serine/threonine kinase 2.	0.568
ENSCVAP00000017074	bag4	ENSCVAP00000017074	ENSCVAP00000002728	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	BCL2 associated athanogene 4.	0.539
ENSCVAP00000017074	ptgs2	ENSCVAP00000017074	ENSCVAP00000025500	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Prostaglandin-endoperoxide synthase 2b.	0.605
ENSCVAP00000017074	vegfa	ENSCVAP00000017074	ENSCVAP00000023279	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.485
ENSCVAP00000027713	ENSCVAP00000011876	ENSCVAP00000027713	ENSCVAP00000011876	Teneurin N-terminal domain-containing protein.	Uncharacterized protein.	0.836
ENSCVAP00000027713	LOC107101723	ENSCVAP00000027713	ENSCVAP00000028466	Teneurin N-terminal domain-containing protein.	Uncharacterized protein.	0.560
ENSCVAP00000028612	vegfa	ENSCVAP00000028612	ENSCVAP00000023279	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.900