25 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sec23a	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
	RING1	Ring finger protein 1. (389 aa)
	osr1	Odd-skipped related transcription factor 1. (272 aa)
	LOC107103139	Sp8 transcription factor b. (452 aa)
	pdlim7	PDZ and LIM domain 7. (423 aa)
	ARL6	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family. (192 aa)
	LOC107083538	Uncharacterized protein. (190 aa)
	sp9	Sp9 transcription factor. (439 aa)
	dlx5	Distal-less homeobox 5a. (286 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	LOC107095104	Fin bud initiation factor b. (206 aa)
	rnf2	Ring finger protein 2. (342 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (1167 aa)
	tbx5	T-box transcription factor 5a. (524 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
	dlx6	Distal-less homeobox 6a. (246 aa)
	osr2	Odd-skipped related transciption factor 2. (273 aa)
	hand2	Heart and neural crest derivatives expressed 2. (244 aa)
	bhlha9	Basic helix-loop-helix family, member a9. (310 aa)
	ENSCVAP00000032151	Uncharacterized protein. (97 aa)
	nipbl	Nipped-B protein. (2319 aa)
	crbn	Cereblon. (446 aa)
	med12	Mediator complex subunit 12. (2062 aa)
	LOC107082097	Lon N-terminal domain-containing protein. (337 aa)
	rspo2	R-spondin 2. (246 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dlx5	dlx6	ENSCVAP00000007043	ENSCVAP00000024522	Distal-less homeobox 5a.	Distal-less homeobox 6a.	0.825
dlx5	hand2	ENSCVAP00000007043	ENSCVAP00000030051	Distal-less homeobox 5a.	Heart and neural crest derivatives expressed 2.	0.402
dlx6	dlx5	ENSCVAP00000024522	ENSCVAP00000007043	Distal-less homeobox 6a.	Distal-less homeobox 5a.	0.825
dlx6	hand2	ENSCVAP00000024522	ENSCVAP00000030051	Distal-less homeobox 6a.	Heart and neural crest derivatives expressed 2.	0.405
hand2	dlx5	ENSCVAP00000030051	ENSCVAP00000007043	Heart and neural crest derivatives expressed 2.	Distal-less homeobox 5a.	0.402
hand2	dlx6	ENSCVAP00000030051	ENSCVAP00000024522	Heart and neural crest derivatives expressed 2.	Distal-less homeobox 6a.	0.405
hand2	tbx5	ENSCVAP00000030051	ENSCVAP00000019091	Heart and neural crest derivatives expressed 2.	T-box transcription factor 5a.	0.665
tbx5	hand2	ENSCVAP00000019091	ENSCVAP00000030051	T-box transcription factor 5a.	Heart and neural crest derivatives expressed 2.	0.665