(22 nodes) Positive regulation of JUN kinase activity network (Cyprinodon variegatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dkk1	Dickkopf WNT signaling pathway inhibitor 1a. (261 aa)
	LOC107097523	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (484 aa)
	map3k13	Mitogen-activated protein kinase kinase kinase. (1002 aa)
	ENSCVAP00000017074	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (64 aa)
	axin1	Axin 1. (845 aa)
	dusp19	Dual specificity phosphatase 19a. (211 aa)
	LOC107086387	Uncharacterized protein. (926 aa)
	LOC107086406	Endoplasmic reticulum to nucleus signaling 2. (973 aa)
	LOC107097051	Uncharacterized protein. (883 aa)
	ENSCVAP00000011893	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (305 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (416 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (655 aa)
	LOC107095718	SCY domain-containing protein. (110 aa)
	ern1	Endoplasmic reticulum to nucleus signaling 1. (1063 aa)
	LOC107096283	Dual specificity phosphatase 19b. (203 aa)
	LOC107102657	Uncharacterized protein. (143 aa)
	ENSCVAP00000023340	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
	sash1	SAM and SH3 domain containing 1a. (1350 aa)
	Fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1579 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (532 aa)
	Fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (560 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000011893	ENSCVAP00000017074	ENSCVAP00000011893	ENSCVAP00000017074	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.938
ENSCVAP00000011893	map2k7	ENSCVAP00000011893	ENSCVAP00000008899	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 7.	0.749
ENSCVAP00000017074	ENSCVAP00000011893	ENSCVAP00000017074	ENSCVAP00000011893	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.938
ENSCVAP00000017074	LOC107086387	ENSCVAP00000017074	ENSCVAP00000014033	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.400
ENSCVAP00000017074	LOC107086406	ENSCVAP00000017074	ENSCVAP00000013079	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Endoplasmic reticulum to nucleus signaling 2.	0.400
ENSCVAP00000017074	LOC107095718	ENSCVAP00000017074	ENSCVAP00000002241	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	SCY domain-containing protein.	0.431
ENSCVAP00000017074	LOC107097523	ENSCVAP00000017074	ENSCVAP00000030943	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.938
ENSCVAP00000017074	ern1	ENSCVAP00000017074	ENSCVAP00000001910	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Endoplasmic reticulum to nucleus signaling 1.	0.400
ENSCVAP00000017074	tnfrsf11a	ENSCVAP00000017074	ENSCVAP00000002416	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	0.578
Fzd5	fzd4	ENSCVAP00000030032	ENSCVAP00000015278	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.417
LOC107086387	ENSCVAP00000017074	ENSCVAP00000014033	ENSCVAP00000017074	Uncharacterized protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.400
LOC107086406	ENSCVAP00000017074	ENSCVAP00000013079	ENSCVAP00000017074	Endoplasmic reticulum to nucleus signaling 2.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.400
LOC107086406	ern1	ENSCVAP00000013079	ENSCVAP00000001910	Endoplasmic reticulum to nucleus signaling 2.	Endoplasmic reticulum to nucleus signaling 1.	0.902
LOC107095718	ENSCVAP00000017074	ENSCVAP00000002241	ENSCVAP00000017074	SCY domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.431
LOC107096283	map2k7	ENSCVAP00000001004	ENSCVAP00000008899	Dual specificity phosphatase 19b.	Mitogen-activated protein kinase kinase 7.	0.529
LOC107097523	ENSCVAP00000017074	ENSCVAP00000030943	ENSCVAP00000017074	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.938
LOC107097523	map2k7	ENSCVAP00000030943	ENSCVAP00000008899	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 7.	0.749
dkk1	fzd4	ENSCVAP00000030114	ENSCVAP00000015278	Dickkopf WNT signaling pathway inhibitor 1a.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.412
dusp19	map2k7	ENSCVAP00000014073	ENSCVAP00000008899	Dual specificity phosphatase 19a.	Mitogen-activated protein kinase kinase 7.	0.529
ern1	ENSCVAP00000017074	ENSCVAP00000001910	ENSCVAP00000017074	Endoplasmic reticulum to nucleus signaling 1.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.400