36 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	exd2	Exonuclease 3'-5' domain containing 2. (671 aa)
	LOC107094846	HD domain-containing protein. (424 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (507 aa)
	dna2	DNA replication helicase/nuclease 2. (1358 aa)
	ENSCVAP00000025174	HD domain-containing protein. (393 aa)
	pold1	DNA polymerase. (1105 aa)
	primpol	Primase and polymerase (DNA-directed). (521 aa)
	zranb3	Zinc finger, RAN-binding domain containing 3. (703 aa)
	Gen1	Chromo_2 domain-containing protein. (523 aa)
	LOC107096926	Uncharacterized protein. (558 aa)
	ENSCVAP00000018664	Uncharacterized protein. (129 aa)
	tonsl	Tonsoku-like, DNA repair protein. (1433 aa)
	rfwd3	Ring finger and WD repeat domain 3. (529 aa)
	mms22l	MMS22-like, DNA repair protein. (1230 aa)
	atrx	ATRX chromatin remodeler. (1892 aa)
	LOC107099910	BLM RecQ like helicase. (1091 aa)
	fancm	Uncharacterized protein. (1764 aa)
	eme1	Essential meiotic structure-specific endonuclease 1. (522 aa)
	ENSCVAP00000010146	Tower domain-containing protein. (2271 aa)
	pole	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2017 aa)
	cenpx	Centromere protein X. (114 aa)
	ENSCVAP00000007189	HD domain-containing protein. (161 aa)
	ENSCVAP00000007153	HD domain-containing protein. (144 aa)
	ZNF830	Zinc finger protein 830. (336 aa)
	fbh1	F-box DNA helicase 1. (882 aa)
	timeless	Timeless circadian clock. (1251 aa)
	ENSCVAP00000000721	Uncharacterized protein. (212 aa)
	EME2	ERCC4 domain-containing protein. (448 aa)
	traip	TRAF-interacting protein. (448 aa)
	thoc1	THO complex 1. (654 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2502 aa)
	LOC107082340	SET domain and mariner transposase fusion gene. (283 aa)
	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (884 aa)
	DONSON	Downstream neighbor of SON. (533 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (692 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DONSON	fancm	ENSCVAP00000029801	ENSCVAP00000013080	Downstream neighbor of SON.	Uncharacterized protein.	0.597
DONSON	primpol	ENSCVAP00000029801	ENSCVAP00000021279	Downstream neighbor of SON.	Primase and polymerase (DNA-directed).	0.465
EME2	ENSCVAP00000000721	ENSCVAP00000000612	ENSCVAP00000000721	ERCC4 domain-containing protein.	Uncharacterized protein.	0.454
EME2	Gen1	ENSCVAP00000000612	ENSCVAP00000020350	ERCC4 domain-containing protein.	Chromo_2 domain-containing protein.	0.454
EME2	LOC107099910	ENSCVAP00000000612	ENSCVAP00000014694	ERCC4 domain-containing protein.	BLM RecQ like helicase.	0.471
EME2	dna2	ENSCVAP00000000612	ENSCVAP00000025528	ERCC4 domain-containing protein.	DNA replication helicase/nuclease 2.	0.618
EME2	eme1	ENSCVAP00000000612	ENSCVAP00000012079	ERCC4 domain-containing protein.	Essential meiotic structure-specific endonuclease 1.	0.770
EME2	fancm	ENSCVAP00000000612	ENSCVAP00000013080	ERCC4 domain-containing protein.	Uncharacterized protein.	0.648
EME2	mre11	ENSCVAP00000000612	ENSCVAP00000029597	ERCC4 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.495
EME2	pold1	ENSCVAP00000000612	ENSCVAP00000023009	ERCC4 domain-containing protein.	DNA polymerase.	0.534
EME2	rad51	ENSCVAP00000000612	ENSCVAP00000029603	ERCC4 domain-containing protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.484
ENSCVAP00000000721	EME2	ENSCVAP00000000721	ENSCVAP00000000612	Uncharacterized protein.	ERCC4 domain-containing protein.	0.454
ENSCVAP00000000721	ENSCVAP00000010146	ENSCVAP00000000721	ENSCVAP00000010146	Uncharacterized protein.	Tower domain-containing protein.	0.588
ENSCVAP00000000721	Gen1	ENSCVAP00000000721	ENSCVAP00000020350	Uncharacterized protein.	Chromo_2 domain-containing protein.	0.632
ENSCVAP00000000721	LOC107099910	ENSCVAP00000000721	ENSCVAP00000014694	Uncharacterized protein.	BLM RecQ like helicase.	0.760
ENSCVAP00000000721	atr	ENSCVAP00000000721	ENSCVAP00000030889	Uncharacterized protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.700
ENSCVAP00000000721	dna2	ENSCVAP00000000721	ENSCVAP00000025528	Uncharacterized protein.	DNA replication helicase/nuclease 2.	0.806
ENSCVAP00000000721	eme1	ENSCVAP00000000721	ENSCVAP00000012079	Uncharacterized protein.	Essential meiotic structure-specific endonuclease 1.	0.647
ENSCVAP00000000721	exd2	ENSCVAP00000000721	ENSCVAP00000028827	Uncharacterized protein.	Exonuclease 3'-5' domain containing 2.	0.657
ENSCVAP00000000721	fancm	ENSCVAP00000000721	ENSCVAP00000013080	Uncharacterized protein.	Uncharacterized protein.	0.838