(61 nodes) Intermediate filament cytoskeleton organization network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107088464	Zgc:158846; Belongs to the intermediate filament family. (529 aa)
	Dst	Si:ch211-165e15.1. (270 aa)
	ENSCVAP00000031102	Uncharacterized protein. (3003 aa)
	LOC107090755	Keratin 98; Belongs to the intermediate filament family. (403 aa)
	LOC107090756	IF rod domain-containing protein; Belongs to the intermediate filament family. (413 aa)
	agfg1	ArfGAP with FG repeats 1a. (588 aa)
	LOC107083023	Wu:fi04e12. (2477 aa)
	LOC107081735	IF rod domain-containing protein; Belongs to the intermediate filament family. (456 aa)
	LOC107090836	Plectin a. (4290 aa)
	PKP1	Plakophilin 1. (706 aa)
	LOC107100579	Envoplakin a. (1927 aa)
	ENSCVAP00000027573	Uncharacterized protein. (266 aa)
	ENSCVAP00000027568	Uncharacterized protein. (556 aa)
	nefh	IF rod domain-containing protein; Belongs to the intermediate filament family. (774 aa)
	ENSCVAP00000024153	IF rod domain-containing protein; Belongs to the intermediate filament family. (228 aa)
	LOC107104914	IF rod domain-containing protein; Belongs to the intermediate filament family. (421 aa)
	LOC107098452	NudE neurodevelopment protein 1-like 1b. (337 aa)
	LOC107094613	PARP alpha-helical domain-containing protein. (764 aa)
	prph	Peripherin; Belongs to the intermediate filament family. (494 aa)
	ppl	Periplakin. (1763 aa)
	LOC107081353	IF rod domain-containing protein; Belongs to the intermediate filament family. (192 aa)
	ENSCVAP00000018765	Vimentin-related 1; Belongs to the intermediate filament family. (227 aa)
	dsp	Desmoplakin a. (2255 aa)
	LOC107104024	Uncharacterized protein. (717 aa)
	klhl24	Kelch-like family member 24a. (596 aa)
	DST	Dystonin. (5034 aa)
	ENSCVAP00000017007	Uncharacterized protein. (887 aa)
	ENSCVAP00000016928	Calponin-homology (CH) domain-containing protein. (907 aa)
	LOC107090752	Keratin 99; Belongs to the intermediate filament family. (435 aa)
	LOC107090753	Keratin 15; Belongs to the intermediate filament family. (424 aa)
	LOC107090754	IF rod domain-containing protein; Belongs to the intermediate filament family. (405 aa)
	LOC107088569	Keratin 5; Belongs to the intermediate filament family. (535 aa)
	LOC107090776	Si:ch211-156l18.7; Belongs to the intermediate filament family. (411 aa)
	LOC107088571	Keratin 8; Belongs to the intermediate filament family. (449 aa)
	LOC107088570	Keratin 8; Belongs to the intermediate filament family. (521 aa)
	LOC107088573	Keratin 18a, tandem duplicate 1; Belongs to the intermediate filament family. (434 aa)
	LOC107104617	Envoplakin b. (2036 aa)
	ENSCVAP00000014055	Uncharacterized protein. (501 aa)
	vps54	VPS54 subunit of GARP complex. (877 aa)
	LOC107089164	Plakophilin 1. (739 aa)
	nefl	Neurofilament, light polypeptide b; Belongs to the intermediate filament family. (588 aa)
	LOC107100615	Plectin b. (5802 aa)
	nefm	Neurofilament, medium polypeptide a; Belongs to the intermediate filament family. (954 aa)
	NEFL	Neurofilament light; Belongs to the intermediate filament family. (554 aa)
	LOC107097664	IF rod domain-containing protein; Belongs to the intermediate filament family. (466 aa)
	LOC107084824	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (449 aa)
	LOC107102459	NudE neurodevelopment protein 1-like 1a. (344 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	LOC107098299	Vimentin like; Belongs to the intermediate filament family. (455 aa)
	LOC107089961	ArfGAP with FG repeats 1b. (376 aa)
	KRT222	Keratin 222; Belongs to the intermediate filament family. (533 aa)
	LOC107092272	IF rod domain-containing protein; Belongs to the intermediate filament family. (376 aa)
	LOC107094471	Notochord granular surface; Belongs to the intermediate filament family. (520 aa)
	bfsp2	Beaded filament structural protein 2, phakinin; Belongs to the intermediate filament family. (417 aa)
	Des	Desmin b; Belongs to the intermediate filament family. (228 aa)
	LOC107104894	Internexin neuronal intermediate filament protein, alpha b; Belongs to the intermediate filament family. (479 aa)
	LOC107104913	IF rod domain-containing protein; Belongs to the intermediate filament family. (351 aa)
	LOC107103861	Desmin a; Belongs to the intermediate filament family. (470 aa)
	LOC107095730	IF rod domain-containing protein; Belongs to the intermediate filament family. (488 aa)
	LOC107087248	Synemin, intermediate filament protein; Belongs to the intermediate filament family. (1000 aa)
	LOC107088477	Keratin 4; Belongs to the intermediate filament family. (466 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Des	LOC107081353	ENSCVAP00000004126	ENSCVAP00000018900	Desmin b; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.492
Dst	ENSCVAP00000014055	ENSCVAP00000031259	ENSCVAP00000014055	Si:ch211-165e15.1.	Uncharacterized protein.	0.588
Dst	ENSCVAP00000017007	ENSCVAP00000031259	ENSCVAP00000017007	Si:ch211-165e15.1.	Uncharacterized protein.	0.498
ENSCVAP00000014055	Dst	ENSCVAP00000014055	ENSCVAP00000031259	Uncharacterized protein.	Si:ch211-165e15.1.	0.588
ENSCVAP00000014055	PKP1	ENSCVAP00000014055	ENSCVAP00000028296	Uncharacterized protein.	Plakophilin 1.	0.403
ENSCVAP00000016928	ENSCVAP00000017007	ENSCVAP00000016928	ENSCVAP00000017007	Calponin-homology (CH) domain-containing protein.	Uncharacterized protein.	0.734
ENSCVAP00000016928	ENSCVAP00000031102	ENSCVAP00000016928	ENSCVAP00000031102	Calponin-homology (CH) domain-containing protein.	Uncharacterized protein.	0.859
ENSCVAP00000017007	Dst	ENSCVAP00000017007	ENSCVAP00000031259	Uncharacterized protein.	Si:ch211-165e15.1.	0.498
ENSCVAP00000017007	ENSCVAP00000016928	ENSCVAP00000017007	ENSCVAP00000016928	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.734
ENSCVAP00000024153	LOC107088477	ENSCVAP00000024153	ENSCVAP00000031938	IF rod domain-containing protein; Belongs to the intermediate filament family.	Keratin 4; Belongs to the intermediate filament family.	0.400
ENSCVAP00000024153	LOC107088570	ENSCVAP00000024153	ENSCVAP00000015851	IF rod domain-containing protein; Belongs to the intermediate filament family.	Keratin 8; Belongs to the intermediate filament family.	0.400
ENSCVAP00000024153	LOC107088571	ENSCVAP00000024153	ENSCVAP00000015892	IF rod domain-containing protein; Belongs to the intermediate filament family.	Keratin 8; Belongs to the intermediate filament family.	0.400
ENSCVAP00000024153	LOC107100579	ENSCVAP00000024153	ENSCVAP00000028052	IF rod domain-containing protein; Belongs to the intermediate filament family.	Envoplakin a.	0.453
ENSCVAP00000024153	ppl	ENSCVAP00000024153	ENSCVAP00000018984	IF rod domain-containing protein; Belongs to the intermediate filament family.	Periplakin.	0.562
ENSCVAP00000027568	ENSCVAP00000027573	ENSCVAP00000027568	ENSCVAP00000027573	Uncharacterized protein.	Uncharacterized protein.	0.488
ENSCVAP00000027573	ENSCVAP00000027568	ENSCVAP00000027573	ENSCVAP00000027568	Uncharacterized protein.	Uncharacterized protein.	0.488
ENSCVAP00000031102	ENSCVAP00000016928	ENSCVAP00000031102	ENSCVAP00000016928	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.859
KRT222	LOC107088477	ENSCVAP00000006484	ENSCVAP00000031938	Keratin 222; Belongs to the intermediate filament family.	Keratin 4; Belongs to the intermediate filament family.	0.400
KRT222	LOC107088570	ENSCVAP00000006484	ENSCVAP00000015851	Keratin 222; Belongs to the intermediate filament family.	Keratin 8; Belongs to the intermediate filament family.	0.400
KRT222	LOC107088571	ENSCVAP00000006484	ENSCVAP00000015892	Keratin 222; Belongs to the intermediate filament family.	Keratin 8; Belongs to the intermediate filament family.	0.400