(27 nodes) Negative regulation of carbohydrate metabolic process network (Cyprinodon variegatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	Park2	RBR-type E3 ubiquitin transferase. (71 aa)
	LOC107101887	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
	LOC107084302	TP53 induced glycolysis regulatory phosphatase a. (266 aa)
	midn	Midnolin. (569 aa)
	cltcl1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1690 aa)
	gckr	Uncharacterized protein. (485 aa)
	LOC107092305	Uncharacterized protein. (422 aa)
	LOC107103921	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (948 aa)
	LOC107092878	E1A binding protein p300 a. (2648 aa)
	fam3a	Family with sequence similarity 3 member A. (234 aa)
	Pask	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (445 aa)
	LOC107082908	Cytochrome c oxidase assembly homolog 11 (yeast). (211 aa)
	ENSCVAP00000015889	Zgc:158343. (184 aa)
	fam3c	Family with sequence similarity 3 member C. (227 aa)
	ENSCVAP00000014430	Uncharacterized protein. (114 aa)
	LOC107104663	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	LOC107085781	TP53 induced glycolysis regulatory phosphatase b. (239 aa)
	ep300	E1A binding protein p300 b. (2766 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (722 aa)
	LOC107090330	Nuclear protein 1a. (76 aa)
	soga1	Suppressor of glucose, autophagy associated 1. (1881 aa)
	ENSCVAP00000009952	Uncharacterized protein. (222 aa)
	LOC107103699	Transforming growth factor beta; Belongs to the TGF-beta family. (349 aa)
	ENSCVAP00000007456	Uncharacterized protein. (158 aa)
	flcn	Folliculin. (556 aa)
	sirt6	Sirtuin 6. (349 aa)
	lepr	Leptin receptor. (1095 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000009952	LOC107084302	ENSCVAP00000009952	ENSCVAP00000025625	Uncharacterized protein.	TP53 induced glycolysis regulatory phosphatase a.	0.905
ENSCVAP00000009952	LOC107085781	ENSCVAP00000009952	ENSCVAP00000012680	Uncharacterized protein.	TP53 induced glycolysis regulatory phosphatase b.	0.901
ENSCVAP00000014430	LOC107103921	ENSCVAP00000014430	ENSCVAP00000021034	Uncharacterized protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.876
LOC107084302	ENSCVAP00000009952	ENSCVAP00000025625	ENSCVAP00000009952	TP53 induced glycolysis regulatory phosphatase a.	Uncharacterized protein.	0.905
LOC107084302	LOC107085781	ENSCVAP00000025625	ENSCVAP00000012680	TP53 induced glycolysis regulatory phosphatase a.	TP53 induced glycolysis regulatory phosphatase b.	0.903
LOC107085781	ENSCVAP00000009952	ENSCVAP00000012680	ENSCVAP00000009952	TP53 induced glycolysis regulatory phosphatase b.	Uncharacterized protein.	0.901
LOC107085781	LOC107084302	ENSCVAP00000012680	ENSCVAP00000025625	TP53 induced glycolysis regulatory phosphatase b.	TP53 induced glycolysis regulatory phosphatase a.	0.903
LOC107092878	LOC107103699	ENSCVAP00000020689	ENSCVAP00000008432	E1A binding protein p300 a.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.532
LOC107101887	LOC107103921	ENSCVAP00000025415	ENSCVAP00000021034	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.971
LOC107101887	LOC107104663	ENSCVAP00000025415	ENSCVAP00000014297	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.900
LOC107101887	cltcl1	ENSCVAP00000025415	ENSCVAP00000030298	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.900
LOC107103699	LOC107092878	ENSCVAP00000008432	ENSCVAP00000020689	Transforming growth factor beta; Belongs to the TGF-beta family.	E1A binding protein p300 a.	0.532
LOC107103699	ep300	ENSCVAP00000008432	ENSCVAP00000025385	Transforming growth factor beta; Belongs to the TGF-beta family.	E1A binding protein p300 b.	0.532
LOC107103921	ENSCVAP00000014430	ENSCVAP00000021034	ENSCVAP00000014430	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Uncharacterized protein.	0.876
LOC107103921	LOC107101887	ENSCVAP00000021034	ENSCVAP00000025415	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.971
LOC107103921	LOC107104663	ENSCVAP00000021034	ENSCVAP00000014297	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.978
LOC107103921	cltcl1	ENSCVAP00000021034	ENSCVAP00000030298	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.961
LOC107104663	LOC107101887	ENSCVAP00000014297	ENSCVAP00000025415	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.900
LOC107104663	LOC107103921	ENSCVAP00000014297	ENSCVAP00000021034	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.978
LOC107104663	cltcl1	ENSCVAP00000014297	ENSCVAP00000030298	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.900