(32 nodes) Synaptic vesicle transport network (Cyprinodon variegatus)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107093198	Adaptin_N domain-containing protein. (554 aa)
	LOC107084593	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
	bloc1s3	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (197 aa)
	LOC107102195	Transmembrane protein 230a. (114 aa)
	bloc1s6	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (171 aa)
	kif5b	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (927 aa)
	KIF5A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (850 aa)
	picalm	Phosphatidylinositol binding clathrin assembly protein b. (736 aa)
	LOC107091037	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (976 aa)
	bloc1s2	Biogenesis of lysosomal organelles complex-1, subunit 2. (179 aa)
	ap3d1	Adaptor related protein complex 3 subunit delta 1. (1267 aa)
	LOC107086677	Kinesin family member 5A, a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1043 aa)
	ENSCVAP00000020208	Adaptin_N domain-containing protein. (158 aa)
	LOC107087826	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (244 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (220 aa)
	Snap91	Uncharacterized protein. (638 aa)
	LOC107094487	Synaptosome associated protein 91b. (578 aa)
	bloc1s5	Biogenesis of lysosomal organelles complex-1, subunit 5, muted. (168 aa)
	LOC107101447	AP-3 complex subunit mu-2. (418 aa)
	ENSCVAP00000001255	Spatacsin_C domain-containing protein. (1125 aa)
	ENSCVAP00000000510	Uncharacterized protein. (79 aa)
	ENSCVAP00000000105	ENTH domain-containing protein. (232 aa)
	LOC107104383	Si:ch211-200p22.4. (546 aa)
	ap3b1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1122 aa)
	LOC107084214	ENTH domain-containing protein. (562 aa)
	ENSCVAP00000013392	ENTH domain-containing protein. (129 aa)
	bloc1s1	Biogenesis of lysosomal organelles complex-1, subunit 1. (125 aa)
	LOC107086812	Transmembrane protein 230b. (119 aa)
	snapin	SNAP associated protein. (129 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	KIF5C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (948 aa)
	LOC107103953	Uncharacterized protein. (282 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000000105	Snap91	ENSCVAP00000000105	ENSCVAP00000019939	ENTH domain-containing protein.	Uncharacterized protein.	0.817
ENSCVAP00000000105	ap3d1	ENSCVAP00000000105	ENSCVAP00000020682	ENTH domain-containing protein.	Adaptor related protein complex 3 subunit delta 1.	0.439
ENSCVAP00000000510	LOC107087826	ENSCVAP00000000510	ENSCVAP00000019731	Uncharacterized protein.	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino.	0.527
ENSCVAP00000000510	bloc1s1	ENSCVAP00000000510	ENSCVAP00000015066	Uncharacterized protein.	Biogenesis of lysosomal organelles complex-1, subunit 1.	0.798
ENSCVAP00000000510	bloc1s2	ENSCVAP00000000510	ENSCVAP00000021728	Uncharacterized protein.	Biogenesis of lysosomal organelles complex-1, subunit 2.	0.573
ENSCVAP00000000510	bloc1s3	ENSCVAP00000000510	ENSCVAP00000030221	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	0.592
ENSCVAP00000000510	bloc1s6	ENSCVAP00000000510	ENSCVAP00000025434	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	0.754
ENSCVAP00000000510	dtnbp1	ENSCVAP00000000510	ENSCVAP00000019766	Uncharacterized protein.	Dystrobrevin binding protein 1b.	0.723
ENSCVAP00000000510	snapin	ENSCVAP00000000510	ENSCVAP00000015598	Uncharacterized protein.	SNAP associated protein.	0.691
ENSCVAP00000013392	ap3d1	ENSCVAP00000013392	ENSCVAP00000020682	ENTH domain-containing protein.	Adaptor related protein complex 3 subunit delta 1.	0.439
ENSCVAP00000020208	LOC107084593	ENSCVAP00000020208	ENSCVAP00000030465	Adaptin_N domain-containing protein.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.977
ENSCVAP00000020208	LOC107093198	ENSCVAP00000020208	ENSCVAP00000020153	Adaptin_N domain-containing protein.	Adaptin_N domain-containing protein.	0.899
ENSCVAP00000020208	LOC107101447	ENSCVAP00000020208	ENSCVAP00000006026	Adaptin_N domain-containing protein.	AP-3 complex subunit mu-2.	0.977
ENSCVAP00000020208	ap3b1	ENSCVAP00000020208	ENSCVAP00000011069	Adaptin_N domain-containing protein.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.900
ENSCVAP00000020208	ap3d1	ENSCVAP00000020208	ENSCVAP00000020682	Adaptin_N domain-containing protein.	Adaptor related protein complex 3 subunit delta 1.	0.992
ENSCVAP00000020208	dtnbp1	ENSCVAP00000020208	ENSCVAP00000019766	Adaptin_N domain-containing protein.	Dystrobrevin binding protein 1b.	0.446
ENSCVAP00000020208	snapin	ENSCVAP00000020208	ENSCVAP00000015598	Adaptin_N domain-containing protein.	SNAP associated protein.	0.588
LOC107084214	ap3d1	ENSCVAP00000012468	ENSCVAP00000020682	ENTH domain-containing protein.	Adaptor related protein complex 3 subunit delta 1.	0.439
LOC107084593	ENSCVAP00000020208	ENSCVAP00000030465	ENSCVAP00000020208	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Adaptin_N domain-containing protein.	0.977
LOC107084593	LOC107093198	ENSCVAP00000030465	ENSCVAP00000020153	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Adaptin_N domain-containing protein.	0.787