(27 nodes) Embryonic viscerocranium morphogenesis network (Cyprinodon variegatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nbas	Neuroblastoma amplified sequence. (2197 aa)
	LOC107087044	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	dlx5	Distal-less homeobox 5a. (286 aa)
	alcam	Activated leukocyte cell adhesion molecule b. (568 aa)
	nipbl	Nipped-B protein. (2319 aa)
	med12	Mediator complex subunit 12. (2062 aa)
	LOC107094605	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
	tbx10	Uncharacterized protein. (302 aa)
	ENSCVAP00000014967	Rad21_Rec8 domain-containing protein. (73 aa)
	ENSCVAP00000014975	Rad21_Rec8_N domain-containing protein. (155 aa)
	dlx3	Distal-less homeobox 3b. (276 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (509 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
	LOC107089630	RAD21 cohesin complex component a. (636 aa)
	mmachc	Metabolism of cobalamin associated C. (270 aa)
	pitx2	Homeobox protein. (312 aa)
	rad21l1	RAD21 cohesin complex component b. (644 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
	tbx1	T-box transcription factor 1. (497 aa)
	gnptab	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1243 aa)
	dlx1	Distal-less homeobox 1a. (254 aa)
	dlx2	Distal-less homeobox 2b. (278 aa)
	hand2	Heart and neural crest derivatives expressed 2. (244 aa)
	LOC107082378	RNA polymerase I and III subunit D. (114 aa)
	ENSCVAP00000032151	Uncharacterized protein. (97 aa)
	fst	Follistatin a. (347 aa)
	bmp2	Bone morphogenetic protein 2b. (413 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000014967	ENSCVAP00000032151	ENSCVAP00000014967	ENSCVAP00000032151	Rad21_Rec8 domain-containing protein.	Uncharacterized protein.	0.846
ENSCVAP00000014967	LOC107089630	ENSCVAP00000014967	ENSCVAP00000017335	Rad21_Rec8 domain-containing protein.	RAD21 cohesin complex component a.	0.900
ENSCVAP00000014967	nipbl	ENSCVAP00000014967	ENSCVAP00000005253	Rad21_Rec8 domain-containing protein.	Nipped-B protein.	0.846
ENSCVAP00000014967	rad21l1	ENSCVAP00000014967	ENSCVAP00000021277	Rad21_Rec8 domain-containing protein.	RAD21 cohesin complex component b.	0.900
ENSCVAP00000014975	ENSCVAP00000032151	ENSCVAP00000014975	ENSCVAP00000032151	Rad21_Rec8_N domain-containing protein.	Uncharacterized protein.	0.846
ENSCVAP00000014975	nipbl	ENSCVAP00000014975	ENSCVAP00000005253	Rad21_Rec8_N domain-containing protein.	Nipped-B protein.	0.846
ENSCVAP00000032151	ENSCVAP00000014967	ENSCVAP00000032151	ENSCVAP00000014967	Uncharacterized protein.	Rad21_Rec8 domain-containing protein.	0.846
ENSCVAP00000032151	ENSCVAP00000014975	ENSCVAP00000032151	ENSCVAP00000014975	Uncharacterized protein.	Rad21_Rec8_N domain-containing protein.	0.846
ENSCVAP00000032151	LOC107089630	ENSCVAP00000032151	ENSCVAP00000017335	Uncharacterized protein.	RAD21 cohesin complex component a.	0.846
ENSCVAP00000032151	rad21l1	ENSCVAP00000032151	ENSCVAP00000021277	Uncharacterized protein.	RAD21 cohesin complex component b.	0.846
LOC107087044	LOC107094605	ENSCVAP00000008168	ENSCVAP00000001484	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.901
LOC107087044	wnt4	ENSCVAP00000008168	ENSCVAP00000017160	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.618
LOC107089630	ENSCVAP00000014967	ENSCVAP00000017335	ENSCVAP00000014967	RAD21 cohesin complex component a.	Rad21_Rec8 domain-containing protein.	0.900
LOC107089630	ENSCVAP00000032151	ENSCVAP00000017335	ENSCVAP00000032151	RAD21 cohesin complex component a.	Uncharacterized protein.	0.846
LOC107089630	nipbl	ENSCVAP00000017335	ENSCVAP00000005253	RAD21 cohesin complex component a.	Nipped-B protein.	0.846
LOC107089630	rad21l1	ENSCVAP00000017335	ENSCVAP00000021277	RAD21 cohesin complex component a.	RAD21 cohesin complex component b.	0.901
LOC107094605	LOC107087044	ENSCVAP00000001484	ENSCVAP00000008168	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.901
LOC107094605	wnt4	ENSCVAP00000001484	ENSCVAP00000017160	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.618
bmp2	dlx5	ENSCVAP00000011041	ENSCVAP00000007043	Bone morphogenetic protein 2b.	Distal-less homeobox 5a.	0.490
bmp2	fst	ENSCVAP00000011041	ENSCVAP00000031034	Bone morphogenetic protein 2b.	Follistatin a.	0.501