(11 nodes) Dopamine receptor binding network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107096617	Prostaglandin E receptor 1a (subtype EP1); Belongs to the G-protein coupled receptor 1 family. (377 aa)
	gna12	G protein subunit alpha 12. (385 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (769 aa)
	LOC107100329	Guanine nucleotide binding protein (G protein), alpha 13b. (378 aa)
	LOC107093424	Prostaglandin E receptor 1c (subtype EP1). (431 aa)
	PALM	Paralemmin. (417 aa)
	LOC107102520	Uncharacterized protein. (413 aa)
	cav2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	LOC107087666	Prostaglandin E receptor 1b (subtype EP1). (366 aa)
	Dnajc14	Jiv90 domain-containing protein. (191 aa)
	LOC107093746	Paralemmin 1b. (223 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107100329	LOC107102520	ENSCVAP00000021715	ENSCVAP00000007729	Guanine nucleotide binding protein (G protein), alpha 13b.	Uncharacterized protein.	0.900
LOC107100329	gna12	ENSCVAP00000021715	ENSCVAP00000028449	Guanine nucleotide binding protein (G protein), alpha 13b.	G protein subunit alpha 12.	0.901
LOC107102520	LOC107100329	ENSCVAP00000007729	ENSCVAP00000021715	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.900
LOC107102520	gna12	ENSCVAP00000007729	ENSCVAP00000028449	Uncharacterized protein.	G protein subunit alpha 12.	0.901
gna12	LOC107100329	ENSCVAP00000028449	ENSCVAP00000021715	G protein subunit alpha 12.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.901
gna12	LOC107102520	ENSCVAP00000028449	ENSCVAP00000007729	G protein subunit alpha 12.	Uncharacterized protein.	0.901