(97 nodes) Neuromuscular process network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	abl2	Tyrosine-protein kinase. (1189 aa)
	LOC107089538	Uncharacterized protein. (1695 aa)
	LOC107095276	Uncharacterized protein. (727 aa)
	ENSCVAP00000007412	Uncharacterized protein. (167 aa)
	r3hdm2	R3H domain containing 2. (1073 aa)
	LOC107099035	Dynactin 1a. (1263 aa)
	lrrc45	Leucine rich repeat containing 45. (674 aa)
	LOC107087116	R3H domain containing 1. (1021 aa)
	vti1a	Vesicle transport through interaction with t-SNAREs 1A. (224 aa)
	LOC107090710	Troponin C type 1b (slow). (161 aa)
	arpp21	Uncharacterized protein. (642 aa)
	LOC107087687	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1305 aa)
	LOC107098345	Otoferlin b. (1632 aa)
	LOC107083859	Troponin I type 2b (skeletal, fast), tandem duplicate 1. (177 aa)
	agtpbp1	ATP/GTP binding protein 1. (1160 aa)
	opa3	Outer mitochondrial membrane lipid metabolism regulator OPA3. (156 aa)
	ENSCVAP00000007456	Uncharacterized protein. (158 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	Park2	RBR-type E3 ubiquitin transferase. (71 aa)
	pou4f2	POU domain protein. (385 aa)
	stac3	SH3 and cysteine rich domain 3. (332 aa)
	LOC107087248	Synemin, intermediate filament protein; Belongs to the intermediate filament family. (1000 aa)
	ush1c	Usher syndrome 1C. (861 aa)
	LOC107095031	Troponin I4b, tandem duplicate 2. (181 aa)
	LOC107095041	Uncharacterized protein. (183 aa)
	hexb	Beta-hexosaminidase. (546 aa)
	LOC107088166	Troponin C type 1a (slow). (161 aa)
	LOC107098884	Homer scaffold protein 1b. (358 aa)
	LOC107080813	Clarin 1. (213 aa)
	get1	Guided entry of tail-anchored proteins factor 1. (170 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1158 aa)
	grin2a	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1506 aa)
	ENSCVAP00000012826	Troponin I type 1a (skeletal, slow). (190 aa)
	pou4f1	POU domain protein. (369 aa)
	vps54	VPS54 subunit of GARP complex. (877 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (838 aa)
	STAC2	SH3 and cysteine rich domain 2. (431 aa)
	igdcc3	Immunoglobulin superfamily, DCC subclass, member 3. (680 aa)
	FXN	Uncharacterized protein. (187 aa)
	LOC107102826	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (442 aa)
	LOC107101697	Gastrulation brain homeobox 1. (322 aa)
	LOC107095337	Zgc:153184. (281 aa)
	LOC107087973	Uncharacterized protein. (692 aa)
	MYCBP2	MYC binding protein 2. (4211 aa)
	hexa	Beta-hexosaminidase. (535 aa)
	ENSCVAP00000016349	Uncharacterized protein. (369 aa)
	TNNI2	Troponin I2, fast skeletal type. (171 aa)
	TNNI2-2	Troponin I2, fast skeletal type. (172 aa)
	stac	SH3 and cysteine rich domain. (348 aa)
	penk	Proenkephalin a. (240 aa)
	LOC107089017	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1636 aa)
	ENSCVAP00000018946	Uncharacterized protein. (174 aa)
	abl1	Tyrosine-protein kinase. (1115 aa)
	LOC107094088	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b. (1401 aa)
	LOC107087826	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (244 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
	LOC107081396	Otoferlin a. (1849 aa)
	LOC107099240	Methyl CpG binding protein 2. (937 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (495 aa)
	ENSCVAP00000022025	ANF_receptor domain-containing protein. (358 aa)
	Slitrk6	SLIT and NTRK-like family, member 6. (834 aa)
	LOC107085523	GTP cyclohydrolase 2. (241 aa)
	LOC107083844	GTP cyclohydrolase 1. (254 aa)
	slc17a8	Solute carrier family 17 member 8. (582 aa)
	LOC107096795	Dynactin 1b. (1139 aa)
	gm2a	GM2 ganglioside activator. (199 aa)
	ENSCVAP00000024289	Endothelin receptor type Ab. (353 aa)
	fer1l6	Fer-1 like family member 6. (1695 aa)
	LOC107095032	Troponin I4a. (180 aa)
	ENSCVAP00000025029	Troponin I4b, tandem duplicate 2. (184 aa)
	LOC107099597	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (443 aa)
	ENSCVAP00000025588	EF-hand domain-containing protein. (69 aa)
	LOC107103666	Si:rp71-17i16.4. (175 aa)
	shank3	SH3 and multiple ankyrin repeat domains 3a. (1586 aa)
	LOC107092085	Spartin b. (584 aa)
	tcap	Titin-cap (telethonin). (179 aa)
	hoxc10	Homeobox C10a. (336 aa)
	ENSCVAP00000027726	Uncharacterized protein. (188 aa)
	LOC107089161	Troponin I type 1b (skeletal, slow). (170 aa)
	ENSCVAP00000028331	Uncharacterized protein. (330 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (623 aa)
	ENSCVAP00000028571	Proline-rich transmembrane protein 2. (166 aa)
	LOC107095960	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1313 aa)
	LOC107099399	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1081 aa)
	ucn	Urotensin 1. (144 aa)
	LOC107102177	Transmembrane protein 150C. (237 aa)
	tmem150c	Transmembrane protein 150C. (238 aa)
	TNNI2-3	Troponin I2, fast skeletal type. (172 aa)
	pnkd	Si:ch73-71c20.5. (154 aa)
	LOC107082894	CAP-ZIP_m domain-containing protein. (396 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	LOC107101505	PNKD metallo-beta-lactamase domain containing. (359 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (448 aa)
	ptprq	Protein tyrosine phosphatase receptor type Q. (2198 aa)
	LOC107083869	Uncharacterized protein. (664 aa)
	LOC107100309	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b. (1799 aa)
	Grin2b	ANF_receptor domain-containing protein. (322 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000007412	GRIN3A	ENSCVAP00000007412	ENSCVAP00000012632	Uncharacterized protein.	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.560
ENSCVAP00000012826	ENSCVAP00000025588	ENSCVAP00000012826	ENSCVAP00000025588	Troponin I type 1a (skeletal, slow).	EF-hand domain-containing protein.	0.824
ENSCVAP00000012826	LOC107083859	ENSCVAP00000012826	ENSCVAP00000005050	Troponin I type 1a (skeletal, slow).	Troponin I type 2b (skeletal, fast), tandem duplicate 1.	0.631
ENSCVAP00000012826	LOC107088166	ENSCVAP00000012826	ENSCVAP00000010473	Troponin I type 1a (skeletal, slow).	Troponin C type 1a (slow).	0.883
ENSCVAP00000012826	LOC107090710	ENSCVAP00000012826	ENSCVAP00000031725	Troponin I type 1a (skeletal, slow).	Troponin C type 1b (slow).	0.895
ENSCVAP00000012826	LOC107103666	ENSCVAP00000012826	ENSCVAP00000025599	Troponin I type 1a (skeletal, slow).	Si:rp71-17i16.4.	0.824
ENSCVAP00000012826	TNNI2	ENSCVAP00000012826	ENSCVAP00000016862	Troponin I type 1a (skeletal, slow).	Troponin I2, fast skeletal type.	0.634
ENSCVAP00000012826	TNNI2-2	ENSCVAP00000012826	ENSCVAP00000016920	Troponin I type 1a (skeletal, slow).	Troponin I2, fast skeletal type.	0.633
ENSCVAP00000012826	TNNI2-3	ENSCVAP00000012826	ENSCVAP00000030980	Troponin I type 1a (skeletal, slow).	Troponin I2, fast skeletal type.	0.634
ENSCVAP00000016349	MYCBP2	ENSCVAP00000016349	ENSCVAP00000016012	Uncharacterized protein.	MYC binding protein 2.	0.930
ENSCVAP00000022025	GRIN3A	ENSCVAP00000022025	ENSCVAP00000012632	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.560
ENSCVAP00000022025	LOC107095960	ENSCVAP00000022025	ENSCVAP00000029150	ANF_receptor domain-containing protein.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.538
ENSCVAP00000025029	ENSCVAP00000025588	ENSCVAP00000025029	ENSCVAP00000025588	Troponin I4b, tandem duplicate 2.	EF-hand domain-containing protein.	0.770
ENSCVAP00000025029	LOC107083859	ENSCVAP00000025029	ENSCVAP00000005050	Troponin I4b, tandem duplicate 2.	Troponin I type 2b (skeletal, fast), tandem duplicate 1.	0.569
ENSCVAP00000025029	LOC107088166	ENSCVAP00000025029	ENSCVAP00000010473	Troponin I4b, tandem duplicate 2.	Troponin C type 1a (slow).	0.769
ENSCVAP00000025029	LOC107090710	ENSCVAP00000025029	ENSCVAP00000031725	Troponin I4b, tandem duplicate 2.	Troponin C type 1b (slow).	0.769
ENSCVAP00000025029	LOC107103666	ENSCVAP00000025029	ENSCVAP00000025599	Troponin I4b, tandem duplicate 2.	Si:rp71-17i16.4.	0.770
ENSCVAP00000025029	TNNI2	ENSCVAP00000025029	ENSCVAP00000016862	Troponin I4b, tandem duplicate 2.	Troponin I2, fast skeletal type.	0.572
ENSCVAP00000025029	TNNI2-2	ENSCVAP00000025029	ENSCVAP00000016920	Troponin I4b, tandem duplicate 2.	Troponin I2, fast skeletal type.	0.571
ENSCVAP00000025029	TNNI2-3	ENSCVAP00000025029	ENSCVAP00000030980	Troponin I4b, tandem duplicate 2.	Troponin I2, fast skeletal type.	0.568