(22 nodes) Regulation of histone H3-K9 methylation network (Cyprinodon variegatus)

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Your Input:
	LOC107093321	Lysine (K)-specific demethylase 4B. (1222 aa)
	myb	V-myb avian myeloblastosis viral oncogene homolog. (594 aa)
	ehmt2	Euchromatic histone-lysine N-methyltransferase 2. (1130 aa)
	sirt1	Sirtuin 1. (691 aa)
	LOC107097910	PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (385 aa)
	ENSCVAP00000013077	SET domain-containing protein. (176 aa)
	prdm12	PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (371 aa)
	atrx	ATRX chromatin remodeler. (1892 aa)
	kdm4a	PHD-type domain-containing protein. (292 aa)
	kdm4c	Lysine (K)-specific demethylase 4C. (1534 aa)
	ENSCVAP00000018664	Uncharacterized protein. (129 aa)
	LOC107098659	Euchromatic histone-lysine N-methyltransferase 1a. (770 aa)
	ENSCVAP00000019490	Lysine (K)-specific demethylase 4A, genome duplicate b. (357 aa)
	jarid2	Jumonji, AT rich interactive domain 2b. (1451 aa)
	LOC107099240	Methyl CpG binding protein 2. (937 aa)
	ehmt1	Euchromatic histone-lysine N-methyltransferase 1b. (1279 aa)
	dnmt1	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1501 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (856 aa)
	LOC107102789	Uncharacterized protein. (595 aa)
	brca1	Uncharacterized protein. (1314 aa)
	rif1	Replication timing regulatory factor 1. (2380 aa)
	ENSCVAP00000032681	Uncharacterized protein. (201 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000013077	LOC107098659	ENSCVAP00000013077	ENSCVAP00000018720	SET domain-containing protein.	Euchromatic histone-lysine N-methyltransferase 1a.	0.895
ENSCVAP00000013077	dnmt1	ENSCVAP00000013077	ENSCVAP00000027344	SET domain-containing protein.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.533
ENSCVAP00000013077	kdm1a	ENSCVAP00000013077	ENSCVAP00000028102	SET domain-containing protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.507
ENSCVAP00000013077	sirt1	ENSCVAP00000013077	ENSCVAP00000004473	SET domain-containing protein.	Sirtuin 1.	0.403
ENSCVAP00000018664	LOC107099240	ENSCVAP00000018664	ENSCVAP00000020494	Uncharacterized protein.	Methyl CpG binding protein 2.	0.687
ENSCVAP00000018664	brca1	ENSCVAP00000018664	ENSCVAP00000031835	Uncharacterized protein.	Uncharacterized protein.	0.412
ENSCVAP00000018664	dnmt1	ENSCVAP00000018664	ENSCVAP00000027344	Uncharacterized protein.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.404
ENSCVAP00000019490	ENSCVAP00000032681	ENSCVAP00000019490	ENSCVAP00000032681	Lysine (K)-specific demethylase 4A, genome duplicate b.	Uncharacterized protein.	0.898
ENSCVAP00000019490	kdm1a	ENSCVAP00000019490	ENSCVAP00000028102	Lysine (K)-specific demethylase 4A, genome duplicate b.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.554
ENSCVAP00000019490	kdm4a	ENSCVAP00000019490	ENSCVAP00000016512	Lysine (K)-specific demethylase 4A, genome duplicate b.	PHD-type domain-containing protein.	0.437
ENSCVAP00000032681	ENSCVAP00000019490	ENSCVAP00000032681	ENSCVAP00000019490	Uncharacterized protein.	Lysine (K)-specific demethylase 4A, genome duplicate b.	0.898
ENSCVAP00000032681	LOC107102789	ENSCVAP00000032681	ENSCVAP00000030807	Uncharacterized protein.	Uncharacterized protein.	0.851
ENSCVAP00000032681	kdm1a	ENSCVAP00000032681	ENSCVAP00000028102	Uncharacterized protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.554
LOC107093321	kdm1a	ENSCVAP00000000166	ENSCVAP00000028102	Lysine (K)-specific demethylase 4B.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.554
LOC107098659	ENSCVAP00000013077	ENSCVAP00000018720	ENSCVAP00000013077	Euchromatic histone-lysine N-methyltransferase 1a.	SET domain-containing protein.	0.895
LOC107098659	dnmt1	ENSCVAP00000018720	ENSCVAP00000027344	Euchromatic histone-lysine N-methyltransferase 1a.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.533
LOC107098659	kdm1a	ENSCVAP00000018720	ENSCVAP00000028102	Euchromatic histone-lysine N-methyltransferase 1a.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.507
LOC107098659	sirt1	ENSCVAP00000018720	ENSCVAP00000004473	Euchromatic histone-lysine N-methyltransferase 1a.	Sirtuin 1.	0.403
LOC107099240	ENSCVAP00000018664	ENSCVAP00000020494	ENSCVAP00000018664	Methyl CpG binding protein 2.	Uncharacterized protein.	0.687
LOC107099240	atrx	ENSCVAP00000020494	ENSCVAP00000016016	Methyl CpG binding protein 2.	ATRX chromatin remodeler.	0.687