(24 nodes) Endochondral bone morphogenesis network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCVAP00000032067	Uncharacterized protein. (245 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	tsku	Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (368 aa)
	mef2d	Myocyte enhancer factor 2d. (580 aa)
	LOC107080807	Peroxisomal biogenesis factor 7. (227 aa)
	anxa6	Annexin. (660 aa)
	ENSCVAP00000026236	Uncharacterized protein. (116 aa)
	LOC107088237	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (722 aa)
	ext2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
	trip11	Thyroid hormone receptor interactor 11. (1968 aa)
	LOC107103972	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (739 aa)
	rap1b	Uncharacterized protein. (184 aa)
	LOC107090729	Uncharacterized protein. (207 aa)
	LOC107105197	SERPIN domain-containing protein; Belongs to the serpin family. (424 aa)
	serpinh1	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (405 aa)
	LOC107101124	MADS-box domain-containing protein. (569 aa)
	LOC107089165	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1052 aa)
	LOC107087044	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	LOC107103249	Uncharacterized protein. (185 aa)
	ift80	Intraflagellar transport 80 homolog (Chlamydomonas). (777 aa)
	LOC107094605	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000026236	LOC107080807	ENSCVAP00000026236	ENSCVAP00000027642	Uncharacterized protein.	Peroxisomal biogenesis factor 7.	0.978
LOC107080807	ENSCVAP00000026236	ENSCVAP00000027642	ENSCVAP00000026236	Peroxisomal biogenesis factor 7.	Uncharacterized protein.	0.978
LOC107087044	LOC107094605	ENSCVAP00000008168	ENSCVAP00000001484	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.901
LOC107090729	LOC107103249	ENSCVAP00000017535	ENSCVAP00000007023	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC107090729	rap1b	ENSCVAP00000017535	ENSCVAP00000017552	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC107094605	LOC107087044	ENSCVAP00000001484	ENSCVAP00000008168	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.901
LOC107103249	LOC107090729	ENSCVAP00000007023	ENSCVAP00000017535	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC107103249	rap1b	ENSCVAP00000007023	ENSCVAP00000017552	Uncharacterized protein.	Uncharacterized protein.	0.900
rap1b	LOC107090729	ENSCVAP00000017552	ENSCVAP00000017535	Uncharacterized protein.	Uncharacterized protein.	0.900
rap1b	LOC107103249	ENSCVAP00000017552	ENSCVAP00000007023	Uncharacterized protein.	Uncharacterized protein.	0.900