STRINGSTRING
LOC107101656 LOC107101656 lhx1 lhx1 nek8 nek8 ENSCVAP00000015157 ENSCVAP00000015157 tmem59l tmem59l irx3 irx3 pax2 pax2 ILK ILK ENSCVAP00000009704 ENSCVAP00000009704 smo smo Ttc26 Ttc26 invs invs LOC107089939 LOC107089939 ENSCVAP00000006673 ENSCVAP00000006673 lzts2 lzts2 LOC107084459 LOC107084459 LOC107096868 LOC107096868 ENSCVAP00000003849 ENSCVAP00000003849 Efhc2 Efhc2 LOC107098481 LOC107098481 LOC107087256 LOC107087256 pkd1 pkd1 tcf21 tcf21 zmpste24 zmpste24 LOC107084008 LOC107084008 wt1 wt1 cfap298 cfap298 ctnnbip1 ctnnbip1 pax8 pax8 Gcnt3 Gcnt3 LOC107093694 LOC107093694 ENSCVAP00000028481 ENSCVAP00000028481 ENSCVAP00000028286 ENSCVAP00000028286 LOC107089788 LOC107089788 greb1 greb1 pkd2 pkd2 klhl2 klhl2 LOC107103085 LOC107103085 LOC107084421 LOC107084421 klhl3 klhl3 wnt6 wnt6 ahi1 ahi1 ENSCVAP00000021102 ENSCVAP00000021102 bmp4 bmp4 LOC107088450 LOC107088450 LOC107090161 LOC107090161 fras1 fras1 bbs5 bbs5 LOC107081559 LOC107081559 lzts3 lzts3 LOC107087916 LOC107087916 pax5 pax5 GREM1 GREM1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC107101656Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (160 aa)
lhx1LIM homeobox 1a. (407 aa)
nek8Protein kinase domain-containing protein. (694 aa)
ENSCVAP00000015157Heparan sulfate 2-O-sulfotransferase 1b. (295 aa)
tmem59lTransmembrane protein 59-like. (340 aa)
irx3Iroquois homeobox 3a. (429 aa)
pax2Paired box 2a. (391 aa)
ILKIntegrin linked kinase. (452 aa)
ENSCVAP00000009704Tetratricopeptide repeat domain 26. (405 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (809 aa)
Ttc26Uncharacterized protein. (140 aa)
invsInversin. (940 aa)
LOC107089939Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (172 aa)
ENSCVAP00000006673Uncharacterized protein. (139 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (695 aa)
LOC107084459Mothers against decapentaplegic homolog. (516 aa)
LOC107096868Bone morphogenetic protein 16. (476 aa)
ENSCVAP00000003849Pax2_C domain-containing protein. (85 aa)
Efhc2Uncharacterized protein. (318 aa)
LOC107098481WT1 transcription factor a. (427 aa)
LOC107087256Uncharacterized protein. (436 aa)
pkd1Polycystic kidney disease 1a. (4547 aa)
tcf21Transcription factor 21. (182 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
LOC107084008Epithelial cell adhesion molecule. (298 aa)
wt1WT1 transcription factor b. (421 aa)
cfap298Cilia and flagella associated protein 298. (290 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
pax8Paired box 8. (376 aa)
Gcnt3Glucosaminyl (N-acetyl) transferase 3, mucin type. (442 aa)
LOC107093694Iroquois homeobox 1b. (441 aa)
ENSCVAP00000028481Protein kinase domain-containing protein. (510 aa)
ENSCVAP00000028286ANK_REP_REGION domain-containing protein. (1004 aa)
LOC107089788T-box transcription factor Ta. (421 aa)
greb1Growth regulating estrogen receptor binding 1. (1791 aa)
pkd2Polycystic kidney disease 2. (888 aa)
klhl2Kelch-like family member 2. (605 aa)
LOC107103085Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (252 aa)
LOC107084421Iroquois homeobox 1a. (496 aa)
klhl3Kelch-like family member 3. (630 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ahi1Abelson helper integration site 1. (1178 aa)
ENSCVAP00000021102MH2 domain-containing protein. (204 aa)
bmp4Bone morphogenetic protein 4. (399 aa)
LOC107088450Mothers against decapentaplegic homolog. (503 aa)
LOC107090161COMM domain containing 5. (211 aa)
fras1Fraser extracellular matrix complex subunit 1. (3934 aa)
bbs5Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family. (341 aa)
LOC107081559Paired domain-containing protein. (136 aa)
lzts3Leucine zipper, putative tumor suppressor family member 3b. (1122 aa)
LOC107087916Uncharacterized protein. (437 aa)
pax5Paired box 5. (370 aa)
GREM1Gremlin. (184 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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