(23 nodes) Cellular response to hydrogen peroxide network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	kdm6b	Lysine (K)-specific demethylase 6B, a. (2093 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (627 aa)
	LOC107088618	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (527 aa)
	sirt1	Sirtuin 1. (691 aa)
	LOC107082057	Nuclear factor, erythroid 2-like 2a. (647 aa)
	LOC107102657	Uncharacterized protein. (143 aa)
	trpa1	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1075 aa)
	ENSCVAP00000022091	Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (461 aa)
	znf277	Zinc finger protein 277. (500 aa)
	LOC107085767	Nuclear factor, erythroid 2-like 2a. (653 aa)
	oser1	Oxidative stress responsive serine-rich 1. (364 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (822 aa)
	FXN	Uncharacterized protein. (187 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (640 aa)
	impact	Impact RWD domain protein. (317 aa)
	ENSCVAP00000010514	Cytochrome P450, family 1, subfamily C, polypeptide 2. (338 aa)
	ENSCVAP00000010443	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (529 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (722 aa)
	plekha1	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (393 aa)
	ect2	Epithelial cell transforming 2. (1047 aa)
	aqp1	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
	park7	Parkinson protein 7. (189 aa)
	LOC107082570	Lysine (K)-specific demethylase 6B, b. (1772 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107082570	plekha1	ENSCVAP00000007394	ENSCVAP00000025957	Lysine (K)-specific demethylase 6B, b.	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b.	0.716
kdm6b	plekha1	ENSCVAP00000007411	ENSCVAP00000025957	Lysine (K)-specific demethylase 6B, a.	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b.	0.716
plekha1	LOC107082570	ENSCVAP00000025957	ENSCVAP00000007394	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b.	Lysine (K)-specific demethylase 6B, b.	0.716
plekha1	kdm6b	ENSCVAP00000025957	ENSCVAP00000007411	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b.	Lysine (K)-specific demethylase 6B, a.	0.716
ripk1	tnfaip3	ENSCVAP00000004942	ENSCVAP00000014276	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	Tumor necrosis factor, alpha-induced protein 3.	0.972
tnfaip3	ripk1	ENSCVAP00000014276	ENSCVAP00000004942	Tumor necrosis factor, alpha-induced protein 3.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.972