STRINGSTRING
LOC107090161 LOC107090161 tcf21 tcf21 LOC107081655 LOC107081655 pkd1 pkd1 TBX2 TBX2 LOC107098481 LOC107098481 Efhc2 Efhc2 LOC107096868 LOC107096868 ret ret kmo kmo LOC107084459 LOC107084459 LOC107094493 LOC107094493 atp6v0d1 atp6v0d1 LOC107085517 LOC107085517 lzts2 lzts2 ENSCVAP00000006673 ENSCVAP00000006673 LOC107089939 LOC107089939 LOC107103699 LOC107103699 tyro3 tyro3 Ttc26 Ttc26 LOC107092123 LOC107092123 smo smo ENSCVAP00000009704 ENSCVAP00000009704 LOC107101284 LOC107101284 LOC107093070 LOC107093070 ILK ILK osr1 osr1 sim1 sim1 ENSCVAP00000012418 ENSCVAP00000012418 NPHS2 NPHS2 ENSCVAP00000012955 ENSCVAP00000012955 irx3 irx3 crlf1 crlf1 LOC107089708 LOC107089708 tmem59l tmem59l smad7 smad7 LOC107102826 LOC107102826 ENSCVAP00000015157 ENSCVAP00000015157 lhx1 lhx1 LOC107082400 LOC107082400 LOC107101656 LOC107101656 GREM1 GREM1 bmper bmper ENSCVAP00000016400 ENSCVAP00000016400 LOC107086851 LOC107086851 LOC107087916 LOC107087916 lzts3 lzts3 mib1 mib1 LOC107088450 LOC107088450 fgf2 fgf2 bmp4 bmp4 yap1 yap1 LOC107095790 LOC107095790 ENSCVAP00000021102 ENSCVAP00000021102 nphs1 nphs1 ahi1 ahi1 magi2 magi2 wnt6 wnt6 smad6 smad6 ENSCVAP00000024289 ENSCVAP00000024289 klhl3 klhl3 LOC107084421 LOC107084421 LOC107103085 LOC107103085 LOC107097790 LOC107097790 klhl2 klhl2 lamb1 lamb1 basp1 basp1 lamb2 lamb2 pkd2 pkd2 ENSCVAP00000026471 ENSCVAP00000026471 greb1 greb1 kank2 kank2 LOC107097582 LOC107097582 LOC107093694 LOC107093694 ctnnbip1 ctnnbip1 prkci prkci wt1 wt1 LOC107084008 LOC107084008 aqp1 aqp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC107090161COMM domain containing 5. (211 aa)
tcf21Transcription factor 21. (182 aa)
LOC107081655Uncharacterized protein. (759 aa)
pkd1Polycystic kidney disease 1a. (4547 aa)
TBX2T-box transcription factor 2. (686 aa)
LOC107098481WT1 transcription factor a. (427 aa)
Efhc2Uncharacterized protein. (318 aa)
LOC107096868Bone morphogenetic protein 16. (476 aa)
retProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (480 aa)
LOC107084459Mothers against decapentaplegic homolog. (516 aa)
LOC107094493Coenzyme Q8B. (631 aa)
atp6v0d1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
LOC107085517Si:dkey-237i9.8. (687 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (695 aa)
ENSCVAP00000006673Uncharacterized protein. (139 aa)
LOC107089939Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (172 aa)
LOC107103699Transforming growth factor beta; Belongs to the TGF-beta family. (349 aa)
tyro3TYRO3 protein tyrosine kinase. (886 aa)
Ttc26Uncharacterized protein. (140 aa)
LOC107092123Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (424 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (809 aa)
ENSCVAP00000009704Tetratricopeptide repeat domain 26. (405 aa)
LOC107101284Thrombospondin, type I, domain containing 7Aa. (1392 aa)
LOC107093070Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
ILKIntegrin linked kinase. (452 aa)
osr1Odd-skipped related transcription factor 1. (272 aa)
sim1Uncharacterized protein. (752 aa)
ENSCVAP00000012418Platelet/endothelial cell adhesion molecule 1. (645 aa)
NPHS2NPHS2 stomatin family member, podocin. (345 aa)
ENSCVAP00000012955Laminin, beta 1b. (797 aa)
irx3Iroquois homeobox 3a. (429 aa)
crlf1Cytokine receptor-like factor 1a. (393 aa)
LOC107089708Cytokine receptor-like factor 1b. (388 aa)
tmem59lTransmembrane protein 59-like. (340 aa)
smad7Mothers against decapentaplegic homolog. (366 aa)
LOC107102826Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (442 aa)
ENSCVAP00000015157Heparan sulfate 2-O-sulfotransferase 1b. (295 aa)
lhx1LIM homeobox 1a. (407 aa)
LOC107082400G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (412 aa)
LOC107101656Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (160 aa)
GREM1Gremlin. (184 aa)
bmperBMP binding endothelial regulator. (589 aa)
ENSCVAP00000016400Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (858 aa)
LOC107086851Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (416 aa)
LOC107087916Uncharacterized protein. (437 aa)
lzts3Leucine zipper, putative tumor suppressor family member 3b. (1122 aa)
mib1Mindbomb E3 ubiquitin protein ligase 1. (1040 aa)
LOC107088450Mothers against decapentaplegic homolog. (503 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
bmp4Bone morphogenetic protein 4. (399 aa)
yap1Yes-associated protein 1. (433 aa)
LOC107095790T-box transcription factor 2a. (596 aa)
ENSCVAP00000021102MH2 domain-containing protein. (204 aa)
nphs1NPHS1 adhesion molecule, nephrin. (1111 aa)
ahi1Abelson helper integration site 1. (1178 aa)
magi2Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1535 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
smad6Mothers against decapentaplegic homolog. (492 aa)
ENSCVAP00000024289Endothelin receptor type Ab. (353 aa)
klhl3Kelch-like family member 3. (630 aa)
LOC107084421Iroquois homeobox 1a. (496 aa)
LOC107103085Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (252 aa)
LOC107097790Mothers against decapentaplegic homolog. (500 aa)
klhl2Kelch-like family member 2. (605 aa)
lamb1Laminin, beta 1a. (1800 aa)
basp1Brain abundant, membrane attached signal protein 1. (215 aa)
lamb2Laminin, beta 2 (laminin S). (1624 aa)
pkd2Polycystic kidney disease 2. (888 aa)
ENSCVAP00000026471Uncharacterized protein. (290 aa)
greb1Growth regulating estrogen receptor binding 1. (1791 aa)
kank2KN motif and ankyrin repeat domains 2. (1014 aa)
LOC107097582Empty spiracles homeobox 1. (233 aa)
LOC107093694Iroquois homeobox 1b. (441 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
wt1WT1 transcription factor b. (421 aa)
LOC107084008Epithelial cell adhesion molecule. (298 aa)
aqp1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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