(19 nodes) Positive regulation of wound healing network (Cyprinodon variegatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	vegfb	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (300 aa)
	ano6	Anoctamin. (922 aa)
	LOC107101324	Uncharacterized protein. (357 aa)
	LOC107100699	SERPIN domain-containing protein; Belongs to the serpin family. (487 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (435 aa)
	LOC107098912	Ras responsive element binding protein 1a. (1793 aa)
	enpp4	Ectonucleotide pyrophosphatase/phosphodiesterase 4. (452 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
	LOC107082057	Nuclear factor, erythroid 2-like 2a. (647 aa)
	ENSCVAP00000022427	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (103 aa)
	LOC107101328	Uncharacterized protein. (363 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (620 aa)
	tbxa2r	Thromboxane A2 receptor. (375 aa)
	fermt1	Fermitin family member 1. (665 aa)
	LOC107090355	Zgc:171965; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	xbp1	X-box binding protein 1. (261 aa)
	LOC107085767	Nuclear factor, erythroid 2-like 2a. (653 aa)
	LOC107090090	SERPIN domain-containing protein; Belongs to the serpin family. (478 aa)
	st3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (306 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107090090	LOC107101324	ENSCVAP00000016402	ENSCVAP00000008845	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.499
LOC107090090	LOC107101328	ENSCVAP00000016402	ENSCVAP00000025725	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.499
LOC107090090	f2	ENSCVAP00000016402	ENSCVAP00000003097	SERPIN domain-containing protein; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.726
LOC107090355	f2	ENSCVAP00000011181	ENSCVAP00000003097	Zgc:171965; Belongs to the G-protein coupled receptor 1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.998
LOC107100699	LOC107101324	ENSCVAP00000008968	ENSCVAP00000008845	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.499
LOC107100699	LOC107101328	ENSCVAP00000008968	ENSCVAP00000025725	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.499
LOC107100699	f2	ENSCVAP00000008968	ENSCVAP00000003097	SERPIN domain-containing protein; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.726
LOC107101324	LOC107090090	ENSCVAP00000008845	ENSCVAP00000016402	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.499
LOC107101324	LOC107100699	ENSCVAP00000008845	ENSCVAP00000008968	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.499
LOC107101324	f2	ENSCVAP00000008845	ENSCVAP00000003097	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.808
LOC107101328	LOC107090090	ENSCVAP00000025725	ENSCVAP00000016402	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.499
LOC107101328	LOC107100699	ENSCVAP00000025725	ENSCVAP00000008968	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.499
LOC107101328	f2	ENSCVAP00000025725	ENSCVAP00000003097	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.808
f2	LOC107090090	ENSCVAP00000003097	ENSCVAP00000016402	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.726
f2	LOC107090355	ENSCVAP00000003097	ENSCVAP00000011181	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Zgc:171965; Belongs to the G-protein coupled receptor 1 family.	0.998
f2	LOC107100699	ENSCVAP00000003097	ENSCVAP00000008968	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.726
f2	LOC107101324	ENSCVAP00000003097	ENSCVAP00000008845	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.808
f2	LOC107101328	ENSCVAP00000003097	ENSCVAP00000025725	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.808
f2	serpine1	ENSCVAP00000003097	ENSCVAP00000009387	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.495
mtor	xbp1	ENSCVAP00000020185	ENSCVAP00000014714	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	X-box binding protein 1.	0.406