(21 nodes) Positive regulation of double-strand break repair via nonhomologous end joining network (Cyprinodon variegatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prkdc	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3872 aa)
	kmt5b	Lysine methyltransferase 5B. (855 aa)
	rif1	Replication timing regulatory factor 1. (2380 aa)
	LOC107082340	SET domain and mariner transposase fusion gene. (283 aa)
	ENSCVAP00000029582	SMC hinge domain-containing protein. (570 aa)
	ENSCVAP00000028757	RING-type domain-containing protein. (536 aa)
	LOC107080723	RING-type domain-containing protein. (210 aa)
	ENSCVAP00000024720	SMC hinge domain-containing protein. (1613 aa)
	ENSCVAP00000020299	RING-type domain-containing protein. (196 aa)
	parp3	Poly [ADP-ribose] polymerase. (525 aa)
	ENSCVAP00000019965	WGR domain-containing protein. (153 aa)
	LOC107092437	Si:dkey-3h3.3. (339 aa)
	wrap53	WD repeat containing, antisense to TP53. (507 aa)
	LOC107096940	SET domain-containing protein. (1939 aa)
	pnkp	Polynucleotide kinase 3'-phosphatase. (600 aa)
	ENSCVAP00000007791	RING-type domain-containing protein. (203 aa)
	LOC107097796	Uncharacterized protein. (250 aa)
	LOC107085383	Structural maintenance of chromosomes flexible hinge domain containing 1. (1708 aa)
	LOC107095145	Zgc:66440. (369 aa)
	LOC107095150	RING-type domain-containing protein. (198 aa)
	LOC107082085	RING-type domain-containing protein. (263 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000019965	prkdc	ENSCVAP00000019965	ENSCVAP00000003403	WGR domain-containing protein.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.432
parp3	prkdc	ENSCVAP00000019966	ENSCVAP00000003403	Poly [ADP-ribose] polymerase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.432
pnkp	prkdc	ENSCVAP00000013658	ENSCVAP00000003403	Polynucleotide kinase 3'-phosphatase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.624
prkdc	ENSCVAP00000019965	ENSCVAP00000003403	ENSCVAP00000019965	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	WGR domain-containing protein.	0.432
prkdc	parp3	ENSCVAP00000003403	ENSCVAP00000019966	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Poly [ADP-ribose] polymerase.	0.432
prkdc	pnkp	ENSCVAP00000003403	ENSCVAP00000013658	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Polynucleotide kinase 3'-phosphatase.	0.624
prkdc	rif1	ENSCVAP00000003403	ENSCVAP00000032456	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Replication timing regulatory factor 1.	0.652
rif1	prkdc	ENSCVAP00000032456	ENSCVAP00000003403	Replication timing regulatory factor 1.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.652