42 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107087706	AP-1 complex subunit gamma. (798 aa)
	LOC107100152	Epsin 3a. (601 aa)
	ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
	AP1M2	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (427 aa)
	RASSF10-2	Ras association domain family member 10. (439 aa)
	synrg	Synergin, gamma. (1452 aa)
	LOC107082456	Epsin 3b. (601 aa)
	LOC107101194	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
	LOC107090293	AP complex subunit beta. (919 aa)
	epn2	Epsin 2. (579 aa)
	ap1b1	AP complex subunit beta. (985 aa)
	cgref1	Cell growth regulator with EF-hand domain 1. (238 aa)
	ENSCVAP00000025427	Uncharacterized protein. (249 aa)
	LOC107101473	Alpha_adaptinC2 domain-containing protein. (841 aa)
	ap1g1	AP-1 complex subunit gamma. (820 aa)
	rassf9	Ras association domain family member 9. (431 aa)
	LOC107103921	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (948 aa)
	ENSCVAP00000020208	Adaptin_N domain-containing protein. (158 aa)
	LOC107093198	Adaptin_N domain-containing protein. (554 aa)
	LOC107082258	DUF1681 domain-containing protein. (252 aa)
	atp6v0b	ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
	aftph	Aftiphilin a. (734 aa)
	LOC107085658	NECAP endocytosis associated 2. (255 aa)
	LOC107089004	NECAP endocytosis associated 1. (263 aa)
	ENSCVAP00000018109	DENN/MADD domain containing 1A. (184 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (167 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	ENSCVAP00000012583	Uncharacterized protein. (58 aa)
	ENSCVAP00000012437	Solute carrier family 18 member 3a. (515 aa)
	ap3b1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1122 aa)
	ap1m1	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
	ap4m1	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (437 aa)
	dab2	DAB adaptor protein 2. (767 aa)
	LOC107082218	Epsin 1. (644 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
	LOC107087306	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa)
	LOC107095773	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (151 aa)
	LOC107095751	Uncharacterized protein. (102 aa)
	LOC107082769	Clat_adaptor_s domain-containing protein. (133 aa)
	atp6v1d	ATPase H+ transporting V1 subunit D. (248 aa)
	LOC107095186	Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family. (444 aa)
	LOC107089997	Solute carrier family 18 member A3. (518 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1M2	AP1S2	ENSCVAP00000030818	ENSCVAP00000017716	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.969
AP1M2	ENSCVAP00000012583	ENSCVAP00000030818	ENSCVAP00000012583	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Uncharacterized protein.	0.765
AP1M2	ENSCVAP00000020208	ENSCVAP00000030818	ENSCVAP00000020208	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Adaptin_N domain-containing protein.	0.499
AP1M2	LOC107087306	ENSCVAP00000030818	ENSCVAP00000001145	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.969
AP1M2	LOC107087706	ENSCVAP00000030818	ENSCVAP00000004960	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-1 complex subunit gamma.	0.983
AP1M2	LOC107090293	ENSCVAP00000030818	ENSCVAP00000028162	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP complex subunit beta.	0.843
AP1M2	LOC107093198	ENSCVAP00000030818	ENSCVAP00000020153	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Adaptin_N domain-containing protein.	0.499
AP1M2	LOC107095186	ENSCVAP00000030818	ENSCVAP00000003002	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.	0.908
AP1M2	LOC107095773	ENSCVAP00000030818	ENSCVAP00000001443	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.969
AP1M2	LOC107103921	ENSCVAP00000030818	ENSCVAP00000021034	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.790
AP1M2	ap1b1	ENSCVAP00000030818	ENSCVAP00000027396	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP complex subunit beta.	0.877
AP1M2	ap1g1	ENSCVAP00000030818	ENSCVAP00000022539	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-1 complex subunit gamma.	0.985
AP1M2	ap1m1	ENSCVAP00000030818	ENSCVAP00000009786	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.908
AP1M2	ap2m1	ENSCVAP00000030818	ENSCVAP00000031359	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.611
AP1M2	ap2s1	ENSCVAP00000030818	ENSCVAP00000017307	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.574
AP1M2	ap3b1	ENSCVAP00000030818	ENSCVAP00000011069	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.665
AP1M2	epn2	ENSCVAP00000030818	ENSCVAP00000028037	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	Epsin 2.	0.403
AP1S2	AP1M2	ENSCVAP00000017716	ENSCVAP00000030818	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.969
AP1S2	ENSCVAP00000012583	ENSCVAP00000017716	ENSCVAP00000012583	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.714
AP1S2	ENSCVAP00000020208	ENSCVAP00000017716	ENSCVAP00000020208	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptin_N domain-containing protein.	0.438