(3 nodes) Endoplasmic reticulum chaperone complex network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)
	xbp1	X-box binding protein 1. (261 aa)
	hyou1	Hypoxia up-regulated 1. (952 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hspa5	hyou1	ENSCVAP00000029709	ENSCVAP00000000460	Heat shock protein 5; Belongs to the heat shock protein 70 family.	Hypoxia up-regulated 1.	0.994
hspa5	xbp1	ENSCVAP00000029709	ENSCVAP00000014714	Heat shock protein 5; Belongs to the heat shock protein 70 family.	X-box binding protein 1.	0.750
hyou1	hspa5	ENSCVAP00000000460	ENSCVAP00000029709	Hypoxia up-regulated 1.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.994
hyou1	xbp1	ENSCVAP00000000460	ENSCVAP00000014714	Hypoxia up-regulated 1.	X-box binding protein 1.	0.700
xbp1	hspa5	ENSCVAP00000014714	ENSCVAP00000029709	X-box binding protein 1.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.750
xbp1	hyou1	ENSCVAP00000014714	ENSCVAP00000000460	X-box binding protein 1.	Hypoxia up-regulated 1.	0.700