(3 nodes) SCF-Skp2 ubiquitin ligase complex network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (409 aa)
	LOC107085705	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
	LOC107084040	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107084040	skp2	ENSCVAP00000014833	ENSCVAP00000024010	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.958
LOC107085705	skp2	ENSCVAP00000030517	ENSCVAP00000024010	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	0.958
skp2	LOC107084040	ENSCVAP00000024010	ENSCVAP00000014833	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.958
skp2	LOC107085705	ENSCVAP00000024010	ENSCVAP00000030517	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.958