102 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	ENSCVAP00000019465	Uncharacterized protein. (668 aa)
	irak1	Interleukin-1 receptor-associated kinase 1. (708 aa)
	LOC107094654	Uncharacterized protein. (445 aa)
	ENSCVAP00000020731	Pyrin domain-containing protein. (100 aa)
	birc2	Baculoviral IAP repeat containing 2. (615 aa)
	irak4	Interleukin-1 receptor-associated kinase 4. (462 aa)
	LOC107082055	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (499 aa)
	card11	Uncharacterized protein. (1160 aa)
	ENSCVAP00000021578	Uncharacterized protein. (662 aa)
	ENSCVAP00000022036	CARD domain-containing protein. (87 aa)
	ENSCVAP00000022348	Si:dkeyp-97b10.3. (398 aa)
	igflr1	IGF-like family receptor 1. (335 aa)
	tradd	Tnfrsf1a-associated via death domain. (292 aa)
	card14	Caspase recruitment domain family, member 14. (963 aa)
	ENSCVAP00000023683	CARD domain-containing protein. (76 aa)
	LOC107095080	Death domain-containing protein. (215 aa)
	ENSCVAP00000023849	CARD domain-containing protein. (208 aa)
	ENSCVAP00000024868	CARD domain-containing protein. (82 aa)
	edar	Ectodysplasin A receptor. (521 aa)
	ENSCVAP00000025647	CARD domain-containing protein. (102 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (430 aa)
	ENSCVAP00000027162	Death domain-containing protein. (160 aa)
	dapk1	Death-associated protein kinase 1. (1445 aa)
	LOC107087477	Uncharacterized protein. (367 aa)
	ENSCVAP00000027693	Pyrin domain-containing protein. (104 aa)
	unc5a	Unc-5 netrin receptor A. (914 aa)
	LOC107104273	Uncharacterized protein. (373 aa)
	malt1	MALT paracaspase 1. (826 aa)
	LOC107094188	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2022 aa)
	LOC107086397	Uncharacterized protein. (826 aa)
	ENSCVAP00000029463	Pyrin domain-containing protein. (1803 aa)
	ENSCVAP00000029728	CARD domain-containing protein. (83 aa)
	ENSCVAP00000029753	Pyrin domain-containing protein. (93 aa)
	LOC107091940	FISNA domain-containing protein. (774 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (460 aa)
	card19	Caspase recruitment domain family, member 19. (191 aa)
	LOC107085087	Nerve growth factor receptor b. (509 aa)
	thoc1	THO complex 1. (654 aa)
	nod2	Nucleotide-binding oligomerization domain containing 2. (986 aa)
	bcl10	BCL10 immune signaling adaptor. (249 aa)
	ENSCVAP00000032222	Pyrin domain-containing protein. (914 aa)
	LOC107089548	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1983 aa)
	dedd2	Death effector domain-containing 1. (282 aa)
	tnfrsf1a	Tumor necrosis factor receptor superfamily, member 1a. (383 aa)
	casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (460 aa)
	ENSCVAP00000000502	CARD domain-containing protein. (94 aa)
	LOC107084990	NLR family, CARD domain containing 3. (1110 aa)
	unc5d	Unc-5 netrin receptor Da. (865 aa)
	ifih1	Interferon induced with helicase C domain 1. (971 aa)
	LOC107097310	MALT paracaspase 2. (808 aa)
	LOC107092852	Tumor necrosis factor receptor superfamily, member a. (308 aa)
	ENSCVAP00000001508	Pyrin domain-containing protein. (111 aa)
	LOC107090603	Uncharacterized protein. (497 aa)
	LOC107090604	Uncharacterized protein. (508 aa)
	ENSCVAP00000001879	Uncharacterized protein. (949 aa)
	tnfrsf21	Tumor necrosis factor receptor superfamily, member 21. (684 aa)
	LOC107081901	Uncharacterized protein; Belongs to the peptidase C14A family. (386 aa)
	nfkb2	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (773 aa)
	ENSCVAP00000003282	CARD domain-containing protein. (98 aa)
	LOC107081895	Uncharacterized protein; Belongs to the peptidase C14A family. (410 aa)
	ENSCVAP00000003302	CARD domain-containing protein. (89 aa)
	LOC107096158	P53-induced death domain protein 1. (918 aa)
	LOC107096835	Uncharacterized protein. (749 aa)
	ENSCVAP00000004858	Pyrin domain-containing protein. (109 aa)
	ENSCVAP00000004903	Pyrin domain-containing protein. (255 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (627 aa)
	LOC107092921	Uncharacterized protein. (1946 aa)
	LOC107084435	Unc-5 netrin receptor C. (923 aa)
	nfkb1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (893 aa)
	ENSCVAP00000006380	CARD domain-containing protein. (120 aa)
	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain. (209 aa)
	ENSCVAP00000007339	CARD domain-containing protein. (98 aa)
	ENSCVAP00000007351	CARD domain-containing protein. (94 aa)
	card9	CARD domain-containing protein. (543 aa)
	ENSCVAP00000007577	Pyrin domain-containing protein. (129 aa)
	CARD10	Caspase recruitment domain family member 10. (1023 aa)
	ENSCVAP00000008478	Death domain-containing protein. (150 aa)
	ENSCVAP00000008573	CARD domain-containing protein. (90 aa)
	LOC107082315	Neurotrophin receptor associated death domain. (395 aa)
	dthd1	Death domain containing 1. (595 aa)
	apaf1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1256 aa)
	ENSCVAP00000010382	Zgc:174906. (216 aa)
	ENSCVAP00000011109	Uncharacterized protein. (149 aa)
	LOC107101768	Uncharacterized protein. (196 aa)
	LOC107098228	NACHT domain-containing protein. (745 aa)
	pea15	Proliferation and apoptosis adaptor protein 15. (130 aa)
	ENSCVAP00000012356	Uncharacterized protein. (419 aa)
	Ank3	Death domain-containing protein. (117 aa)
	LOC107099932	Unc-5 netrin receptor B. (919 aa)
	LOC107088506	Uncharacterized protein. (319 aa)
	LOC107103405	CARD_2 domain-containing protein. (570 aa)
	ENSCVAP00000016344	Uncharacterized protein; Belongs to the peptidase C14A family. (438 aa)
	LOC107103375	CARD domain-containing protein. (223 aa)
	ENSCVAP00000016828	Uncharacterized protein. (914 aa)
	LOC107086824	Uncharacterized protein; Belongs to the peptidase C14A family. (477 aa)
	ENSCVAP00000017097	Uncharacterized protein; Belongs to the peptidase C14A family. (340 aa)
	ENSCVAP00000017952	CARD domain-containing protein. (98 aa)
	dedd	Death effector domain containing. (401 aa)
	ENSCVAP00000018334	Uncharacterized protein. (895 aa)
	unc5c	Unc-5 netrin receptor C. (954 aa)
	nod1	Nucleotide-binding oligomerization domain containing 1. (921 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARD10	LOC107097310	ENSCVAP00000008371	ENSCVAP00000001254	Caspase recruitment domain family member 10.	MALT paracaspase 2.	0.466
CARD10	malt1	ENSCVAP00000008371	ENSCVAP00000028589	Caspase recruitment domain family member 10.	MALT paracaspase 1.	0.466
ENSCVAP00000000502	ENSCVAP00000024868	ENSCVAP00000000502	ENSCVAP00000024868	CARD domain-containing protein.	CARD domain-containing protein.	0.709
ENSCVAP00000000502	LOC107088506	ENSCVAP00000000502	ENSCVAP00000015716	CARD domain-containing protein.	Uncharacterized protein.	0.437
ENSCVAP00000000502	apaf1	ENSCVAP00000000502	ENSCVAP00000010055	CARD domain-containing protein.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.715
ENSCVAP00000003282	ENSCVAP00000024868	ENSCVAP00000003282	ENSCVAP00000024868	CARD domain-containing protein.	CARD domain-containing protein.	0.781
ENSCVAP00000003282	LOC107088506	ENSCVAP00000003282	ENSCVAP00000015716	CARD domain-containing protein.	Uncharacterized protein.	0.472
ENSCVAP00000003282	apaf1	ENSCVAP00000003282	ENSCVAP00000010055	CARD domain-containing protein.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.715
ENSCVAP00000003282	birc2	ENSCVAP00000003282	ENSCVAP00000020970	CARD domain-containing protein.	Baculoviral IAP repeat containing 2.	0.425
ENSCVAP00000003282	myd88	ENSCVAP00000003282	ENSCVAP00000019101	CARD domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.411
ENSCVAP00000003302	ENSCVAP00000024868	ENSCVAP00000003302	ENSCVAP00000024868	CARD domain-containing protein.	CARD domain-containing protein.	0.709
ENSCVAP00000003302	LOC107088506	ENSCVAP00000003302	ENSCVAP00000015716	CARD domain-containing protein.	Uncharacterized protein.	0.437
ENSCVAP00000003302	apaf1	ENSCVAP00000003302	ENSCVAP00000010055	CARD domain-containing protein.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.715
ENSCVAP00000006380	ENSCVAP00000024868	ENSCVAP00000006380	ENSCVAP00000024868	CARD domain-containing protein.	CARD domain-containing protein.	0.781
ENSCVAP00000006380	LOC107088506	ENSCVAP00000006380	ENSCVAP00000015716	CARD domain-containing protein.	Uncharacterized protein.	0.472
ENSCVAP00000006380	apaf1	ENSCVAP00000006380	ENSCVAP00000010055	CARD domain-containing protein.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.715
ENSCVAP00000006380	birc2	ENSCVAP00000006380	ENSCVAP00000020970	CARD domain-containing protein.	Baculoviral IAP repeat containing 2.	0.425
ENSCVAP00000006380	myd88	ENSCVAP00000006380	ENSCVAP00000019101	CARD domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.411
ENSCVAP00000007339	ENSCVAP00000024868	ENSCVAP00000007339	ENSCVAP00000024868	CARD domain-containing protein.	CARD domain-containing protein.	0.709
ENSCVAP00000007339	LOC107088506	ENSCVAP00000007339	ENSCVAP00000015716	CARD domain-containing protein.	Uncharacterized protein.	0.437