(23 nodes) Ribosomal protein S5 domain 2-type fold, subgroup network (Cyprinodon variegatus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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protein homology

Your Input:
	EEF2	Eukaryotic translation elongation factor 2. (863 aa)
	LOC107096218	Glucuronokinase with putative uridyl pyrophosphorylase. (536 aa)
	lonp2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (802 aa)
	EFL1	Elongation factor like GTPase 1. (1070 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (1003 aa)
	ENSCVAP00000012342	Uncharacterized protein. (97 aa)
	LOC107096963	Eukaryotic translation elongation factor 2b. (858 aa)
	pms2	PMS1 homolog 2, mismatch repair system component. (844 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
	mlh3	MutL homolog 3 (E. coli). (1087 aa)
	rps2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (490 aa)
	galk1	Galactokinase 1. (394 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	gfm1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (747 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (719 aa)
	LOC107091052	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1552 aa)
	lonp1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (894 aa)
	mrps9	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (380 aa)
	gfm2	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (765 aa)
	pms1	PMS1 homolog 1, mismatch repair system component. (845 aa)
	mrps5	Mitochondrial ribosomal protein S5. (323 aa)
	Galk2	GalKase_gal_bdg domain-containing protein. (65 aa)
	rps16	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF2	mrps5	ENSCVAP00000004147	ENSCVAP00000028361	Eukaryotic translation elongation factor 2.	Mitochondrial ribosomal protein S5.	0.878
EEF2	mrps9	ENSCVAP00000004147	ENSCVAP00000023990	Eukaryotic translation elongation factor 2.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.933
EEF2	rps16	ENSCVAP00000004147	ENSCVAP00000028979	Eukaryotic translation elongation factor 2.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.975
EEF2	rps2	ENSCVAP00000004147	ENSCVAP00000020985	Eukaryotic translation elongation factor 2.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.989
EFL1	LOC107091052	ENSCVAP00000009808	ENSCVAP00000022779	Elongation factor like GTPase 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.437
EFL1	mrps5	ENSCVAP00000009808	ENSCVAP00000028361	Elongation factor like GTPase 1.	Mitochondrial ribosomal protein S5.	0.878
EFL1	mrps9	ENSCVAP00000009808	ENSCVAP00000023990	Elongation factor like GTPase 1.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.933
EFL1	rps16	ENSCVAP00000009808	ENSCVAP00000028979	Elongation factor like GTPase 1.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.839
EFL1	rps2	ENSCVAP00000009808	ENSCVAP00000020985	Elongation factor like GTPase 1.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.878
ENSCVAP00000012342	mvk	ENSCVAP00000012342	ENSCVAP00000021622	Uncharacterized protein.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.991
Galk2	mvk	ENSCVAP00000028403	ENSCVAP00000021622	GalKase_gal_bdg domain-containing protein.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.540
LOC107091052	EFL1	ENSCVAP00000022779	ENSCVAP00000009808	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor like GTPase 1.	0.437
LOC107091052	gfm2	ENSCVAP00000022779	ENSCVAP00000025301	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.443
LOC107096963	mrps5	ENSCVAP00000015857	ENSCVAP00000028361	Eukaryotic translation elongation factor 2b.	Mitochondrial ribosomal protein S5.	0.878
LOC107096963	mrps9	ENSCVAP00000015857	ENSCVAP00000023990	Eukaryotic translation elongation factor 2b.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.933
LOC107096963	rps16	ENSCVAP00000015857	ENSCVAP00000028979	Eukaryotic translation elongation factor 2b.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.975
LOC107096963	rps2	ENSCVAP00000015857	ENSCVAP00000020985	Eukaryotic translation elongation factor 2b.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.989
eftud2	mrps5	ENSCVAP00000010358	ENSCVAP00000028361	Elongation factor Tu GTP binding domain containing 2.	Mitochondrial ribosomal protein S5.	0.878
eftud2	mrps9	ENSCVAP00000010358	ENSCVAP00000023990	Elongation factor Tu GTP binding domain containing 2.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.933
eftud2	rps16	ENSCVAP00000010358	ENSCVAP00000028979	Elongation factor Tu GTP binding domain containing 2.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.850