(27 nodes) Frizzled domain network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCVAP00000006644	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
	FZD3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (719 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (809 aa)
	LOC107080987	Frizzled related protein. (209 aa)
	LOC107093767	Carboxypeptidase Z. (665 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC107091926	Uncharacterized protein. (339 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (532 aa)
	ENSCVAP00000016777	FZ domain-containing protein. (117 aa)
	fzd10	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (598 aa)
	MUSK	Muscle associated receptor tyrosine kinase. (852 aa)
	ENSCVAP00000023340	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
	CPZ	Carboxypeptidase Z. (657 aa)
	Fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (684 aa)
	sfrp5	Secreted frizzled-related protein 5. (318 aa)
	LOC107094858	Uncharacterized protein. (291 aa)
	ENSCVAP00000028562	Frizzled class receptor 7a; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
	mfrp	Membrane frizzled-related protein. (435 aa)
	LOC107099393	Secreted frizzled-related protein 1a. (304 aa)
	Fzd9	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	LOC107102792	Corin, serine peptidase. (1109 aa)
	Fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (560 aa)
	ENSCVAP00000030951	FZ domain-containing protein. (106 aa)
	ror1	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (950 aa)
	LOC107089501	Sizzled. (283 aa)
	fzd3	Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (709 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000006644	LOC107091926	ENSCVAP00000006644	ENSCVAP00000014972	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.687
ENSCVAP00000006644	fzd4	ENSCVAP00000006644	ENSCVAP00000015278	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.435
ENSCVAP00000006644	ror1	ENSCVAP00000006644	ENSCVAP00000001621	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.955
ENSCVAP00000006644	sfrp2	ENSCVAP00000006644	ENSCVAP00000013859	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2.	0.687
ENSCVAP00000006644	sfrp5	ENSCVAP00000006644	ENSCVAP00000027326	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5.	0.688
ENSCVAP00000016777	fzd4	ENSCVAP00000016777	ENSCVAP00000015278	FZ domain-containing protein.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.442
ENSCVAP00000016777	ror1	ENSCVAP00000016777	ENSCVAP00000001621	FZ domain-containing protein.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.574
ENSCVAP00000023340	LOC107091926	ENSCVAP00000023340	ENSCVAP00000014972	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.674
ENSCVAP00000023340	ror1	ENSCVAP00000023340	ENSCVAP00000001621	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.952
ENSCVAP00000023340	sfrp2	ENSCVAP00000023340	ENSCVAP00000013859	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2.	0.674
ENSCVAP00000023340	sfrp5	ENSCVAP00000023340	ENSCVAP00000027326	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 5.	0.667
ENSCVAP00000028562	fzd4	ENSCVAP00000028562	ENSCVAP00000015278	Frizzled class receptor 7a; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.435
ENSCVAP00000028562	ror1	ENSCVAP00000028562	ENSCVAP00000001621	Frizzled class receptor 7a; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.574
ENSCVAP00000030951	fzd4	ENSCVAP00000030951	ENSCVAP00000015278	FZ domain-containing protein.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.418
ENSCVAP00000030951	ror1	ENSCVAP00000030951	ENSCVAP00000001621	FZ domain-containing protein.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.574
FZD3	Fzd9	ENSCVAP00000006841	ENSCVAP00000029715	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.	0.406
FZD3	LOC107091926	ENSCVAP00000006841	ENSCVAP00000014972	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.713
FZD3	fzd10	ENSCVAP00000006841	ENSCVAP00000021808	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	0.406
FZD3	fzd4	ENSCVAP00000006841	ENSCVAP00000015278	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.478
FZD3	ror1	ENSCVAP00000006841	ENSCVAP00000001621	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.944