(5 nodes) Ubiquitin-activating enzyme E1, Cys active site network (Cyprinodon variegatus)

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Your Input:
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (645 aa)
	LOC107097505	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1012 aa)
	LOC107091497	Ubiquitin-like modifier activating enzyme 3. (452 aa)
	uba1	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1057 aa)
	UBA3	Ubiquitin like modifier activating enzyme 3. (442 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107091497	LOC107097505	ENSCVAP00000011241	ENSCVAP00000017484	Ubiquitin-like modifier activating enzyme 3.	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	0.670
LOC107091497	UBA3	ENSCVAP00000011241	ENSCVAP00000002817	Ubiquitin-like modifier activating enzyme 3.	Ubiquitin like modifier activating enzyme 3.	0.900
LOC107091497	uba1	ENSCVAP00000011241	ENSCVAP00000007771	Ubiquitin-like modifier activating enzyme 3.	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.670
LOC107097505	LOC107091497	ENSCVAP00000017484	ENSCVAP00000011241	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 3.	0.670
LOC107097505	UBA3	ENSCVAP00000017484	ENSCVAP00000002817	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Ubiquitin like modifier activating enzyme 3.	0.670
LOC107097505	uba1	ENSCVAP00000017484	ENSCVAP00000007771	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.903
LOC107097505	uba2	ENSCVAP00000017484	ENSCVAP00000027373	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.406
UBA3	LOC107091497	ENSCVAP00000002817	ENSCVAP00000011241	Ubiquitin like modifier activating enzyme 3.	Ubiquitin-like modifier activating enzyme 3.	0.900
UBA3	LOC107097505	ENSCVAP00000002817	ENSCVAP00000017484	Ubiquitin like modifier activating enzyme 3.	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	0.670
UBA3	uba1	ENSCVAP00000002817	ENSCVAP00000007771	Ubiquitin like modifier activating enzyme 3.	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.670
uba1	LOC107091497	ENSCVAP00000007771	ENSCVAP00000011241	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 3.	0.670
uba1	LOC107097505	ENSCVAP00000007771	ENSCVAP00000017484	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	0.903
uba1	UBA3	ENSCVAP00000007771	ENSCVAP00000002817	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	Ubiquitin like modifier activating enzyme 3.	0.670
uba1	uba2	ENSCVAP00000007771	ENSCVAP00000027373	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.406
uba2	LOC107097505	ENSCVAP00000027373	ENSCVAP00000017484	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	0.406
uba2	uba1	ENSCVAP00000027373	ENSCVAP00000007771	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.406