56 items (Cyprinodon variegatus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107103992	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (449 aa)
	ENSCVAP00000032089	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (122 aa)
	ENSCVAP00000032687	Uncharacterized protein. (180 aa)
	LOC107090107	Uncharacterized protein. (725 aa)
	bmf	Uncharacterized protein. (163 aa)
	nmt1	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (483 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	LOC107099435	BCL2 like 10. (206 aa)
	LOC107080694	DUF4203 domain-containing protein. (335 aa)
	Aven	Apoptosis, caspase activation inhibitor. (282 aa)
	LOC107090059	Diablo, IAP-binding mitochondrial protein a. (250 aa)
	septin5	Septin 5a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (376 aa)
	LOC107090423	Dynein light chain. (89 aa)
	ENSCVAP00000031691	X-linked inhibitor of apoptosis. (296 aa)
	LOC107090351	3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa)
	LOC107101186	Mitogen-activated protein kinase. (379 aa)
	LOC107095977	Cytochrome c, somatic b; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	bad	BCL2 associated agonist of cell death b. (163 aa)
	LOC107080667	Uncharacterized protein. (202 aa)
	LOC107090370	3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa)
	Tep1	Uncharacterized protein. (853 aa)
	mapk1	Mitogen-activated protein kinase. (351 aa)
	LOC107086824	Uncharacterized protein; Belongs to the peptidase C14A family. (477 aa)
	casp7	Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (325 aa)
	LOC107096927	Uncharacterized protein. (193 aa)
	LOC107083382	BCL2 apoptosis regulator b. (227 aa)
	apip	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (245 aa)
	LOC107083354	BCL2 family apoptosis regulator BOK b. (213 aa)
	LOC107088371	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (251 aa)
	LOC107098347	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa)
	YWHAB-2	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (244 aa)
	ENSCVAP00000023693	FIIND domain-containing protein. (453 aa)
	LOC107081867	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (255 aa)
	LOC107081311	Uncharacterized protein. (198 aa)
	LOC107084350	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	npvf	Neuropeptide VF precursor. (202 aa)
	LOC107103712	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
	LOC107103707	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (251 aa)
	LOC107084353	Uncharacterized protein. (466 aa)
	gsdme	Gasdermin Eb. (463 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (430 aa)
	LOC107099974	BH4_2 domain-containing protein. (219 aa)
	LOC107082125	DUF4203 domain-containing protein. (342 aa)
	LOC107082027	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (106 aa)
	LOC107103859	Transmembrane protein 198a. (366 aa)
	tmem198	Transmembrane protein 198b. (362 aa)
	FILIP1L	Filamin A interacting protein 1 like. (1104 aa)
	ppp3r1	Uncharacterized protein. (170 aa)
	LOC107102478	BH4_2 domain-containing protein. (226 aa)
	bcl2l11	Uncharacterized protein. (242 aa)
	ywhaq	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (251 aa)
	LOC107099539	Diablo, IAP-binding mitochondrial protein a. (268 aa)
	apaf1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1256 aa)
	ENSCVAP00000011304	Uncharacterized protein. (147 aa)
	ywhae	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (256 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aven	LOC107082027	ENSCVAP00000029599	ENSCVAP00000001763	Apoptosis, caspase activation inhibitor.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.412
Aven	LOC107084350	ENSCVAP00000029599	ENSCVAP00000025176	Apoptosis, caspase activation inhibitor.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.412
Aven	LOC107095977	ENSCVAP00000029599	ENSCVAP00000013592	Apoptosis, caspase activation inhibitor.	Cytochrome c, somatic b; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.412
Aven	LOC107099974	ENSCVAP00000029599	ENSCVAP00000000251	Apoptosis, caspase activation inhibitor.	BH4_2 domain-containing protein.	0.511
Aven	LOC107102478	ENSCVAP00000029599	ENSCVAP00000008450	Apoptosis, caspase activation inhibitor.	BH4_2 domain-containing protein.	0.511
Aven	Tep1	ENSCVAP00000029599	ENSCVAP00000015177	Apoptosis, caspase activation inhibitor.	Uncharacterized protein.	0.771
Aven	apaf1	ENSCVAP00000029599	ENSCVAP00000010055	Apoptosis, caspase activation inhibitor.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.984
Aven	apip	ENSCVAP00000029599	ENSCVAP00000021944	Apoptosis, caspase activation inhibitor.	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.	0.403
Aven	casp9	ENSCVAP00000029599	ENSCVAP00000026761	Apoptosis, caspase activation inhibitor.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.614
BAX	ENSCVAP00000011304	ENSCVAP00000027282	ENSCVAP00000011304	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.874
BAX	ENSCVAP00000032687	ENSCVAP00000027282	ENSCVAP00000032687	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.475
BAX	LOC107080667	ENSCVAP00000027282	ENSCVAP00000015020	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.992
BAX	LOC107081311	ENSCVAP00000027282	ENSCVAP00000024568	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.903
BAX	LOC107082027	ENSCVAP00000027282	ENSCVAP00000001763	BCL2 associated X, apoptosis regulator.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.961
BAX	LOC107083382	ENSCVAP00000027282	ENSCVAP00000019531	BCL2 associated X, apoptosis regulator.	BCL2 apoptosis regulator b.	0.992
BAX	LOC107084350	ENSCVAP00000027282	ENSCVAP00000025176	BCL2 associated X, apoptosis regulator.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.961
BAX	LOC107090059	ENSCVAP00000027282	ENSCVAP00000029705	BCL2 associated X, apoptosis regulator.	Diablo, IAP-binding mitochondrial protein a.	0.452
BAX	LOC107095977	ENSCVAP00000027282	ENSCVAP00000013592	BCL2 associated X, apoptosis regulator.	Cytochrome c, somatic b; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.961
BAX	LOC107099539	ENSCVAP00000027282	ENSCVAP00000009951	BCL2 associated X, apoptosis regulator.	Diablo, IAP-binding mitochondrial protein a.	0.452
BAX	LOC107099974	ENSCVAP00000027282	ENSCVAP00000000251	BCL2 associated X, apoptosis regulator.	BH4_2 domain-containing protein.	0.991