21 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRC	Tyrosine-protein kinase. (551 aa)
	LOC107098265	Stathmin; Belongs to the stathmin family. (151 aa)
	LOC107091800	Signal transducer and activator of transcription. (787 aa)
	mxd4	MAX dimerization protein 4. (212 aa)
	LOC107091154	ArfGAP with dual PH domains 2. (378 aa)
	LOC107087640	Signal transducer and activator of transcription. (785 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1234 aa)
	LOC107084284	Uncharacterized protein. (377 aa)
	ENSCVAP00000025803	Uncharacterized protein. (383 aa)
	esr1	Estrogen receptor 1. (376 aa)
	ENSCVAP00000025430	Arf-GAP domain-containing protein. (135 aa)
	LOC107104490	Uncharacterized protein. (387 aa)
	wwox	WW domain containing oxidoreductase. (412 aa)
	LOC107083889	APH1B gamma secretase subunit. (258 aa)
	psenen	Presenilin enhancer, gamma-secretase subunit. (101 aa)
	NCSTN	Nicastrin. (701 aa)
	LOC107081657	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (568 aa)
	yap1	Yes-associated protein 1. (433 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1207 aa)
	LOC107099431	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
	ADAP1	ArfGAP with dual PH domains 1. (376 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107081657	SRC	ENSCVAP00000020274	ENSCVAP00000009430	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Tyrosine-protein kinase.	0.517
LOC107083889	LOC107099431	ENSCVAP00000023223	ENSCVAP00000013722	APH1B gamma secretase subunit.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.992
LOC107083889	LOC107104490	ENSCVAP00000023223	ENSCVAP00000024457	APH1B gamma secretase subunit.	Uncharacterized protein.	0.965
LOC107083889	NCSTN	ENSCVAP00000023223	ENSCVAP00000022540	APH1B gamma secretase subunit.	Nicastrin.	0.997
LOC107083889	psenen	ENSCVAP00000023223	ENSCVAP00000022678	APH1B gamma secretase subunit.	Presenilin enhancer, gamma-secretase subunit.	0.997
LOC107087640	LOC107091800	ENSCVAP00000007345	ENSCVAP00000032794	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
LOC107087640	SRC	ENSCVAP00000007345	ENSCVAP00000009430	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.446
LOC107091800	LOC107087640	ENSCVAP00000032794	ENSCVAP00000007345	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
LOC107091800	SRC	ENSCVAP00000032794	ENSCVAP00000009430	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.446
LOC107099431	LOC107083889	ENSCVAP00000013722	ENSCVAP00000023223	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	APH1B gamma secretase subunit.	0.992
LOC107099431	LOC107104490	ENSCVAP00000013722	ENSCVAP00000024457	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.435
LOC107099431	NCSTN	ENSCVAP00000013722	ENSCVAP00000022540	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Nicastrin.	0.994
LOC107099431	psenen	ENSCVAP00000013722	ENSCVAP00000022678	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin enhancer, gamma-secretase subunit.	0.995
LOC107104490	LOC107083889	ENSCVAP00000024457	ENSCVAP00000023223	Uncharacterized protein.	APH1B gamma secretase subunit.	0.965
LOC107104490	LOC107099431	ENSCVAP00000024457	ENSCVAP00000013722	Uncharacterized protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.435
LOC107104490	NCSTN	ENSCVAP00000024457	ENSCVAP00000022540	Uncharacterized protein.	Nicastrin.	0.973
LOC107104490	psenen	ENSCVAP00000024457	ENSCVAP00000022678	Uncharacterized protein.	Presenilin enhancer, gamma-secretase subunit.	0.975
NCSTN	LOC107083889	ENSCVAP00000022540	ENSCVAP00000023223	Nicastrin.	APH1B gamma secretase subunit.	0.997
NCSTN	LOC107099431	ENSCVAP00000022540	ENSCVAP00000013722	Nicastrin.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.994
NCSTN	LOC107104490	ENSCVAP00000022540	ENSCVAP00000024457	Nicastrin.	Uncharacterized protein.	0.973