47 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107084369	Tax1 (human T-cell leukemia virus type I) binding protein 1a. (936 aa)
	irf7	Interferon regulatory factor 7. (439 aa)
	nfkb1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (893 aa)
	LOC107097205	Interferon regulatory factor 3. (463 aa)
	LOC107083304	EF-hand domain-containing protein. (159 aa)
	vwc2	Von Willebrand factor C domain containing 2. (303 aa)
	LOC107100299	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (724 aa)
	nfkb2	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (773 aa)
	LOC107086576	Protein kinase domain-containing protein. (740 aa)
	rnf216	Ring finger protein 216. (820 aa)
	crebbp	CREB binding protein b. (2380 aa)
	ep300	E1A binding protein p300 b. (2766 aa)
	Pin1	Peptidyl-prolyl cis-trans isomerase. (153 aa)
	tomm70	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (578 aa)
	LOC107084913	Basal cell adhesion molecule (Lutheran blood group). (610 aa)
	ENSCVAP00000029664	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (121 aa)
	ikbkb	Inhibitor of nuclear factor kappa B kinase subunit beta. (710 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (319 aa)
	s100b	S100 calcium binding protein, beta (neural). (94 aa)
	rela	V-rel avian reticuloendotheliosis viral oncogene homolog A. (622 aa)
	tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1b. (838 aa)
	nkiras1	NFKB inhibitor interacting Ras-like 1. (120 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (763 aa)
	LOC107092109	High mobility group box 1b. (199 aa)
	LOC107093789	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (580 aa)
	nkiras2	NFKB inhibitor interacting Ras-like 2. (192 aa)
	LOC107104503	Amyloid beta (A4) precursor protein b. (725 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	Ikbke	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (358 aa)
	LOC107100300	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (731 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (724 aa)
	LOC107092878	E1A binding protein p300 a. (2648 aa)
	LOC107088406	Uncharacterized protein. (110 aa)
	LOC107083428	CREB binding protein a. (2444 aa)
	tbk1	TANK-binding kinase 1. (720 aa)
	APP	Amyloid beta precursor protein. (762 aa)
	LOC107103405	CARD_2 domain-containing protein. (570 aa)
	ENSCVAP00000015714	Uncharacterized protein. (81 aa)
	ENSCVAP00000014910	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
	LOC107090890	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (103 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (822 aa)
	REL	REL proto-oncogene, NF-kB subunit. (630 aa)
	LOC107088138	High mobility group box 1a. (201 aa)
	otud5	OTU deubiquitinase 5a. (539 aa)
	LOC107095483	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (304 aa)
	nlrx1	NLR family member X1. (969 aa)
	dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58. (681 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	nfkb1	ENSCVAP00000016722	ENSCVAP00000006220	Amyloid beta precursor protein.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.	0.461
APP	nfkb2	ENSCVAP00000016722	ENSCVAP00000003257	Amyloid beta precursor protein.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100).	0.461
APP	s100b	ENSCVAP00000016722	ENSCVAP00000032826	Amyloid beta precursor protein.	S100 calcium binding protein, beta (neural).	0.505
CHUK	LOC107086576	ENSCVAP00000001539	ENSCVAP00000002893	Component of inhibitor of nuclear factor kappa B kinase complex.	Protein kinase domain-containing protein.	0.944
CHUK	LOC107093789	ENSCVAP00000001539	ENSCVAP00000010683	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.987
CHUK	LOC107095483	ENSCVAP00000001539	ENSCVAP00000009748	Component of inhibitor of nuclear factor kappa B kinase complex.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.958
CHUK	LOC107097205	ENSCVAP00000001539	ENSCVAP00000004552	Component of inhibitor of nuclear factor kappa B kinase complex.	Interferon regulatory factor 3.	0.507
CHUK	REL	ENSCVAP00000001539	ENSCVAP00000014054	Component of inhibitor of nuclear factor kappa B kinase complex.	REL proto-oncogene, NF-kB subunit.	0.682
CHUK	ikbkb	ENSCVAP00000001539	ENSCVAP00000030160	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.952
CHUK	irf7	ENSCVAP00000001539	ENSCVAP00000007018	Component of inhibitor of nuclear factor kappa B kinase complex.	Interferon regulatory factor 7.	0.954
CHUK	nfkb1	ENSCVAP00000001539	ENSCVAP00000006220	Component of inhibitor of nuclear factor kappa B kinase complex.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.	0.959
CHUK	nfkb2	ENSCVAP00000001539	ENSCVAP00000003257	Component of inhibitor of nuclear factor kappa B kinase complex.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100).	0.643
CHUK	nfkbia	ENSCVAP00000001539	ENSCVAP00000001881	Component of inhibitor of nuclear factor kappa B kinase complex.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.958
CHUK	nlrx1	ENSCVAP00000001539	ENSCVAP00000008701	Component of inhibitor of nuclear factor kappa B kinase complex.	NLR family member X1.	0.546
CHUK	rela	ENSCVAP00000001539	ENSCVAP00000032924	Component of inhibitor of nuclear factor kappa B kinase complex.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.682
CHUK	rnf216	ENSCVAP00000001539	ENSCVAP00000002570	Component of inhibitor of nuclear factor kappa B kinase complex.	Ring finger protein 216.	0.453
CHUK	tnfaip3	ENSCVAP00000001539	ENSCVAP00000014276	Component of inhibitor of nuclear factor kappa B kinase complex.	Tumor necrosis factor, alpha-induced protein 3.	0.567
ENSCVAP00000015714	LOC107086576	ENSCVAP00000015714	ENSCVAP00000002893	Uncharacterized protein.	Protein kinase domain-containing protein.	0.406
ENSCVAP00000015714	LOC107092878	ENSCVAP00000015714	ENSCVAP00000020689	Uncharacterized protein.	E1A binding protein p300 a.	0.452
ENSCVAP00000015714	LOC107097205	ENSCVAP00000015714	ENSCVAP00000004552	Uncharacterized protein.	Interferon regulatory factor 3.	0.526