35 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ccnk	Cyclin K; Belongs to the cyclin family. (543 aa)
	LOC107095805	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (810 aa)
	smad2	Mothers against decapentaplegic homolog. (474 aa)
	rbl1	Retinoblastoma-like 1 (p107). (925 aa)
	cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (372 aa)
	rps27a	Ribosomal protein S27a. (181 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (841 aa)
	LOC107084459	Mothers against decapentaplegic homolog. (516 aa)
	sp1	Sp1 transcription factor. (442 aa)
	ccnt1	Cyclin T1; Belongs to the cyclin family. (668 aa)
	ccnq	Cyclin Q; Belongs to the cyclin family. (267 aa)
	tfdp1	Transcription factor. (410 aa)
	ENSCVAP00000012118	E2F_TDP domain-containing protein. (76 aa)
	LOC107101186	Mitogen-activated protein kinase. (379 aa)
	LOC107098778	Mothers against decapentaplegic homolog. (466 aa)
	smad7	Mothers against decapentaplegic homolog. (366 aa)
	mapk1	Mitogen-activated protein kinase. (351 aa)
	ccnt2	Cyclin T2; Belongs to the cyclin family. (695 aa)
	LOC107088450	Mothers against decapentaplegic homolog. (503 aa)
	cdk19	Cyclin-dependent kinase 19. (336 aa)
	Cdk19	Uncharacterized protein. (82 aa)
	ENSCVAP00000021102	MH2 domain-containing protein. (204 aa)
	ENSCVAP00000021667	Ubiquitin-like domain-containing protein. (83 aa)
	rnf111	Ring finger protein 111. (1024 aa)
	ccnc	Cyclin C; Belongs to the cyclin family. (283 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	LOC107087652	JunB proto-oncogene, AP-1 transcription factor subunit b. (329 aa)
	smad3	Mothers against decapentaplegic homolog. (425 aa)
	cdk8	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	e2f4	E2F transcription factor 4. (378 aa)
	LOC107096611	JunB proto-oncogene, AP-1 transcription factor subunit a. (328 aa)
	ENSCVAP00000027729	Multiple endocrine neoplasia I. (444 aa)
	ENSCVAP00000031960	CYCLIN domain-containing protein; Belongs to the cyclin family. (220 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdk19	ENSCVAP00000021102	ENSCVAP00000019990	ENSCVAP00000021102	Uncharacterized protein.	MH2 domain-containing protein.	0.402
Cdk19	ENSCVAP00000031960	ENSCVAP00000019990	ENSCVAP00000031960	Uncharacterized protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.531
Cdk19	LOC107084459	ENSCVAP00000019990	ENSCVAP00000004754	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.402
Cdk19	LOC107088450	ENSCVAP00000019990	ENSCVAP00000018520	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.402
Cdk19	ccnc	ENSCVAP00000019990	ENSCVAP00000023406	Uncharacterized protein.	Cyclin C; Belongs to the cyclin family.	0.951
Cdk19	ccnk	ENSCVAP00000019990	ENSCVAP00000010311	Uncharacterized protein.	Cyclin K; Belongs to the cyclin family.	0.696
Cdk19	ccnq	ENSCVAP00000019990	ENSCVAP00000010756	Uncharacterized protein.	Cyclin Q; Belongs to the cyclin family.	0.483
Cdk19	ccnt1	ENSCVAP00000019990	ENSCVAP00000008934	Uncharacterized protein.	Cyclin T1; Belongs to the cyclin family.	0.531
Cdk19	ccnt2	ENSCVAP00000019990	ENSCVAP00000018296	Uncharacterized protein.	Cyclin T2; Belongs to the cyclin family.	0.531
Cdk19	cdk9	ENSCVAP00000019990	ENSCVAP00000003473	Uncharacterized protein.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.598
ENSCVAP00000012118	ENSCVAP00000021102	ENSCVAP00000012118	ENSCVAP00000021102	E2F_TDP domain-containing protein.	MH2 domain-containing protein.	0.587
ENSCVAP00000012118	LOC107084459	ENSCVAP00000012118	ENSCVAP00000004754	E2F_TDP domain-containing protein.	Mothers against decapentaplegic homolog.	0.849
ENSCVAP00000012118	LOC107088450	ENSCVAP00000012118	ENSCVAP00000018520	E2F_TDP domain-containing protein.	Mothers against decapentaplegic homolog.	0.849
ENSCVAP00000012118	LOC107098778	ENSCVAP00000012118	ENSCVAP00000013086	E2F_TDP domain-containing protein.	Mothers against decapentaplegic homolog.	0.816
ENSCVAP00000012118	SMAD3	ENSCVAP00000012118	ENSCVAP00000025010	E2F_TDP domain-containing protein.	Mothers against decapentaplegic homolog.	0.816
ENSCVAP00000012118	e2f4	ENSCVAP00000012118	ENSCVAP00000025674	E2F_TDP domain-containing protein.	E2F transcription factor 4.	0.901
ENSCVAP00000012118	rbl1	ENSCVAP00000012118	ENSCVAP00000002371	E2F_TDP domain-containing protein.	Retinoblastoma-like 1 (p107).	0.991
ENSCVAP00000012118	smad2	ENSCVAP00000012118	ENSCVAP00000001511	E2F_TDP domain-containing protein.	Mothers against decapentaplegic homolog.	0.816
ENSCVAP00000012118	smad3	ENSCVAP00000012118	ENSCVAP00000024017	E2F_TDP domain-containing protein.	Mothers against decapentaplegic homolog.	0.816
ENSCVAP00000012118	tfdp1	ENSCVAP00000012118	ENSCVAP00000011988	E2F_TDP domain-containing protein.	Transcription factor.	0.993