STRINGSTRING
EFNA5 EFNA5 ENSCVAP00000029398 ENSCVAP00000029398 LOC107095960 LOC107095960 ephb2 ephb2 LOC107099941 LOC107099941 itsn1 itsn1 ENSCVAP00000028288 ENSCVAP00000028288 ENSCVAP00000028279 ENSCVAP00000028279 LOC107090293 LOC107090293 LOC107093741 LOC107093741 LOC107085238 LOC107085238 LOC107099959 LOC107099959 mmp9 mmp9 Arpc5 Arpc5 ENSCVAP00000025647 ENSCVAP00000025647 LOC107101887 LOC107101887 ENSCVAP00000024837 ENSCVAP00000024837 LOC107096191 LOC107096191 YES1 YES1 LOC107095754 LOC107095754 LOC107105123 LOC107105123 LOC107082255 LOC107082255 LOC107082256 LOC107082256 LOC107093502 LOC107093502 pak1 pak1 efnb2 efnb2 LOC107104490 LOC107104490 ephb1 ephb1 LOC107084410 LOC107084410 ACTR3 ACTR3 ENSCVAP00000023282 ENSCVAP00000023282 LOC107083889 LOC107083889 psenen psenen LOC107094019 LOC107094019 arpc4 arpc4 NCSTN NCSTN ENSCVAP00000022025 ENSCVAP00000022025 CDC42 CDC42 LOC107094531 LOC107094531 ENSCVAP00000021338 ENSCVAP00000021338 arpc2 arpc2 LOC107103921 LOC107103921 ENSCVAP00000020099 ENSCVAP00000020099 arpc3 arpc3 PAK3 PAK3 fyn fyn efna1 efna1 rock2 rock2 LOC107094106 LOC107094106 LOC107094679 LOC107094679 was was LOC107094694 LOC107094694 ENSCVAP00000018208 ENSCVAP00000018208 ENSCVAP00000017952 ENSCVAP00000017952 efnb1 efnb1 ap2s1 ap2s1 clta clta LOC107091879 LOC107091879 LOC107087930 LOC107087930 LOC107098137 LOC107098137 fndc3b fndc3b FMN1 FMN1 mmp2 mmp2 LOC107084078 LOC107084078 LOC107084034 LOC107084034 dnm1 dnm1 LOC107102417 LOC107102417 LOC107102251 LOC107102251 ENSCVAP00000014430 ENSCVAP00000014430 LOC107104663 LOC107104663 ENSCVAP00000002447 ENSCVAP00000002447 Epha10 Epha10 LOC107094012 LOC107094012 ENSCVAP00000014209 ENSCVAP00000014209 ENSCVAP00000014079 ENSCVAP00000014079 efnb3 efnb3 vav2 vav2 ENSCVAP00000013741 ENSCVAP00000013741 LOC107099431 LOC107099431 ENSCVAP00000013718 ENSCVAP00000013718 ENSCVAP00000013502 ENSCVAP00000013502 ENSCVAP00000013497 ENSCVAP00000013497 LOC107096517 LOC107096517 pak2 pak2 ENSCVAP00000012583 ENSCVAP00000012583 LOC107090819 LOC107090819 epha7 epha7 LOC107104264 LOC107104264 LOC107099944 LOC107099944 cltb cltb LOC107085266 LOC107085266 ENSCVAP00000010746 ENSCVAP00000010746 VAV1 VAV1 LOC107085917 LOC107085917 LOC107086945 LOC107086945 LOC107097675 LOC107097675 LOC107086129 LOC107086129 SRC SRC PAK2 PAK2 epha3 epha3 Wasl Wasl LOC107095569 LOC107095569 hras hras arhgef7 arhgef7 LOC107082621 LOC107082621 LOC107084406 LOC107084406 cfl2 cfl2 LOC107084408 LOC107084408 LOC107088342 LOC107088342 LOC107097915 LOC107097915 actb actb LOC107100982 LOC107100982 LOC107094101 LOC107094101 LOC107088397 LOC107088397 LOC107088391 LOC107088391 Grin2b Grin2b LOC107089351 LOC107089351 rasa1 rasa1 ENSCVAP00000031975 ENSCVAP00000031975 LOC107090696 LOC107090696 LOC107099262 LOC107099262 LOC107084157 LOC107084157 rock1 rock1 ap2m1 ap2m1 LOC107085118 LOC107085118 LOC107091872 LOC107091872 LOC107100440 LOC107100440 epha4 epha4 cltcl1 cltcl1 cfl1 cfl1 ENSCVAP00000030093 ENSCVAP00000030093 fndc3a fndc3a actr3 actr3 ENSCVAP00000029807 ENSCVAP00000029807
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
ENSCVAP00000029398SAM domain-containing protein. (167 aa)
LOC107095960Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1313 aa)
ephb2Eph receptor B2b. (988 aa)
LOC107099941Eph receptor A2 b. (994 aa)
itsn1Intersectin 1 (SH3 domain protein). (1570 aa)
ENSCVAP00000028288Eph LBD domain-containing protein. (315 aa)
ENSCVAP00000028279Eph receptor A6; Belongs to the protein kinase superfamily. Tyr protein kinase family. (358 aa)
LOC107090293AP complex subunit beta. (919 aa)
LOC107093741Ephrin-A2a; Belongs to the ephrin family. (207 aa)
LOC107085238Uncharacterized protein. (570 aa)
LOC107099959Tyrosine-protein kinase. (547 aa)
mmp9Matrix metallopeptidase 9. (691 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (79 aa)
ENSCVAP00000025647CARD domain-containing protein. (102 aa)
LOC107101887Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
ENSCVAP00000024837WD_REPEATS_REGION domain-containing protein. (163 aa)
LOC107096191Tyrosine-protein kinase. (537 aa)
YES1Tyrosine-protein kinase. (589 aa)
LOC107095754Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
LOC107105123Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
LOC107082255Receptor protein-tyrosine kinase. (1004 aa)
LOC107082256Uncharacterized protein. (191 aa)
LOC107093502Eph receptor B4a. (989 aa)
pak1Non-specific serine/threonine protein kinase. (563 aa)
efnb2Ephrin-B2a; Belongs to the ephrin family. (334 aa)
LOC107104490Uncharacterized protein. (387 aa)
ephb1EPH receptor B1. (984 aa)
LOC107084410Uncharacterized protein. (375 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (433 aa)
ENSCVAP00000023282DH domain-containing protein. (825 aa)
LOC107083889APH1B gamma secretase subunit. (258 aa)
psenenPresenilin enhancer, gamma-secretase subunit. (101 aa)
LOC107094019Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
arpc4Actin related protein 2/3 complex subunit 4. (230 aa)
NCSTNNicastrin. (701 aa)
ENSCVAP00000022025ANF_receptor domain-containing protein. (358 aa)
CDC42Cell division cycle 42. (191 aa)
LOC107094531FH2 domain-containing protein. (1138 aa)
ENSCVAP00000021338Uncharacterized protein. (390 aa)
arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (299 aa)
LOC107103921AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (948 aa)
ENSCVAP00000020099Phorbol-ester/DAG-type domain-containing protein. (126 aa)
arpc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
PAK3Non-specific serine/threonine protein kinase. (554 aa)
fynTyrosine-protein kinase. (537 aa)
efna1Ephrin-A1b; Belongs to the ephrin family. (231 aa)
rock2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1374 aa)
LOC107094106Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (378 aa)
LOC107094679Ephrin-A5a; Belongs to the ephrin family. (229 aa)
wasUncharacterized protein. (536 aa)
LOC107094694Ephrin RBD domain-containing protein; Belongs to the ephrin family. (221 aa)
ENSCVAP00000018208annotation not available (98 aa)
ENSCVAP00000017952CARD domain-containing protein. (98 aa)
efnb1Ephrin-B1; Belongs to the ephrin family. (336 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
LOC107091879Uncharacterized protein. (1084 aa)
LOC107087930T cell lymphoma invasion and metastasis 1a. (1648 aa)
LOC107098137Si:ch73-40a2.1. (861 aa)
fndc3bFibronectin type III domain containing 3Ba. (1207 aa)
FMN1Formin 1. (1287 aa)
mmp2Matrix metallopeptidase 2. (657 aa)
LOC107084078Ephrin-A1a; Belongs to the ephrin family. (221 aa)
LOC107084034Ephrin-A3a; Belongs to the ephrin family. (223 aa)
dnm1Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
LOC107102417Glutamate receptor, ionotropic, N-methyl D-aspartate 1a. (947 aa)
LOC107102251ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (161 aa)
ENSCVAP00000014430Uncharacterized protein. (114 aa)
LOC107104663Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
ENSCVAP00000002447Eph LBD domain-containing protein. (242 aa)
Epha10Eph LBD domain-containing protein. (270 aa)
LOC107094012WH1 domain-containing protein. (339 aa)
ENSCVAP00000014209Protein kinase domain-containing protein. (175 aa)
ENSCVAP00000014079LITAF domain-containing protein. (237 aa)
efnb3Ephrin-B3a; Belongs to the ephrin family. (342 aa)
vav2Vav 2 guanine nucleotide exchange factor. (879 aa)
ENSCVAP00000013741Eph LBD domain-containing protein. (284 aa)
LOC107099431Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
ENSCVAP00000013718Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (352 aa)
ENSCVAP00000013502Uncharacterized protein. (891 aa)
ENSCVAP00000013497FH2 domain-containing protein. (245 aa)
LOC107096517Uncharacterized protein. (375 aa)
pak2Non-specific serine/threonine protein kinase. (528 aa)
ENSCVAP00000012583Uncharacterized protein. (58 aa)
LOC107090819Ephrin RBD domain-containing protein; Belongs to the ephrin family. (321 aa)
epha7Eph receptor A7. (993 aa)
LOC107104264Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (797 aa)
LOC107099944Syndecan binding protein (syntenin) 2. (285 aa)
cltbClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (197 aa)
LOC107085266Zgc:101810; Belongs to the actin family. (394 aa)
ENSCVAP00000010746Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (346 aa)
VAV1Vav guanine nucleotide exchange factor 1. (843 aa)
LOC107085917Vav 3 guanine nucleotide exchange factor b. (794 aa)
LOC107086945Fibronectin type-III domain-containing protein. (682 aa)
LOC107097675Uncharacterized protein. (831 aa)
LOC107086129Uncharacterized protein. (191 aa)
SRCTyrosine-protein kinase. (551 aa)
PAK2Non-specific serine/threonine protein kinase. (510 aa)
epha3Eph receptor A3. (993 aa)
WaslWH1 domain-containing protein. (103 aa)
LOC107095569T cell lymphoma invasion and metastasis 1b. (1528 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
arhgef7Rho guanine nucleotide exchange factor (GEF) 7b. (788 aa)
LOC107082621Eph receptor B3a. (926 aa)
LOC107084406Uncharacterized protein. (375 aa)
cfl2Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
LOC107084408Uncharacterized protein; Belongs to the actin family. (415 aa)
LOC107088342WASP like actin nucleation promoting factor b. (516 aa)
LOC107097915Glutamate receptor, ionotropic, N-methyl D-aspartate 1b. (917 aa)
actbUncharacterized protein. (375 aa)
LOC107100982Uncharacterized protein. (948 aa)
LOC107094101Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
LOC107088397Ephrin RBD domain-containing protein; Belongs to the ephrin family. (260 aa)
LOC107088391Ephrin RBD domain-containing protein; Belongs to the ephrin family. (199 aa)
Grin2bANF_receptor domain-containing protein. (322 aa)
LOC107089351Eph receptor A2 a. (987 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1a. (1048 aa)
ENSCVAP00000031975Eph LBD domain-containing protein. (158 aa)
LOC107090696Eph receptor B2a. (963 aa)
LOC107099262Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (234 aa)
LOC107084157Zgc:86896. (314 aa)
rock1Rho-associated, coiled-coil containing protein kinase 1. (1044 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
LOC107085118Uncharacterized protein. (191 aa)
LOC107091872Eph receptor A4b. (985 aa)
LOC107100440Rho guanine nucleotide exchange factor (GEF) 7a. (748 aa)
epha4Receptor protein-tyrosine kinase. (951 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1690 aa)
cfl1Cofilin 1; Belongs to the actin-binding proteins ADF family. (167 aa)
ENSCVAP00000030093Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (372 aa)
fndc3aFibronectin type III domain containing 3A. (1234 aa)
actr3Uncharacterized protein; Belongs to the actin family. (416 aa)
ENSCVAP00000029807Actin related protein 3. (129 aa)
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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