49 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107085118	Uncharacterized protein. (191 aa)
	LOC107082256	Uncharacterized protein. (191 aa)
	LOC107092854	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
	LOC107093166	Tribbles pseudokinase 3. (350 aa)
	YES1	Tyrosine-protein kinase. (589 aa)
	LOC107096191	Tyrosine-protein kinase. (537 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1724 aa)
	LOC107086129	Uncharacterized protein. (191 aa)
	pik3r2	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (724 aa)
	ENSCVAP00000005673	Ig-like domain-containing protein. (125 aa)
	cd276	CD276 molecule. (298 aa)
	ENSCVAP00000008839	Uncharacterized protein. (261 aa)
	SRC	Tyrosine-protein kinase. (551 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1004 aa)
	map3k8	Mitogen-activated protein kinase kinase kinase 8. (467 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	LOC107084720	Mitogen-activated protein kinase kinase kinase 14a. (873 aa)
	LOC107083639	Uncharacterized protein. (471 aa)
	LOC107103532	MAPK associated protein 1. (486 aa)
	LOC107093724	Uncharacterized protein. (229 aa)
	LOC107095985	Uncharacterized protein. (350 aa)
	pak2	Non-specific serine/threonine protein kinase. (528 aa)
	LOC107099926	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC107099902	Uncharacterized protein. (471 aa)
	LOC107083482	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1207 aa)
	LOC107102211	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae). (260 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	ENSCVAP00000019147	WD_REPEATS_REGION domain-containing protein. (66 aa)
	fyn	Tyrosine-protein kinase. (537 aa)
	PAK3	Non-specific serine/threonine protein kinase. (554 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
	LOC107096308	Thioesterase superfamily member 4. (245 aa)
	LOC107082021	GRB2 related adaptor protein 2a. (274 aa)
	CDC42	Cell division cycle 42. (191 aa)
	LOC107091676	Tyrosine-protein kinase. (510 aa)
	LOC107093973	ADP-ribosylation factor 2b. (934 aa)
	PIK3CA	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1038 aa)
	pak1	Non-specific serine/threonine protein kinase. (563 aa)
	LOC107097814	Uncharacterized protein. (718 aa)
	LOC107099959	Tyrosine-protein kinase. (547 aa)
	vtcn1	V-set domain containing T cell activation inhibitor 1. (272 aa)
	ENSCVAP00000029198	V-akt murine thymoma viral oncogene homolog 3b. (181 aa)
	PAK2	Non-specific serine/threonine protein kinase. (510 aa)
	ENSCVAP00000032381	WD_REPEATS_REGION domain-containing protein. (68 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1234 aa)
	lck	Tyrosine-protein kinase. (500 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSCVAP00000029198	ENSCVAP00000021883	ENSCVAP00000029198	Cell division cycle 42.	V-akt murine thymoma viral oncogene homolog 3b.	0.418
CDC42	LOC107083482	ENSCVAP00000021883	ENSCVAP00000015997	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	LOC107091676	ENSCVAP00000021883	ENSCVAP00000023251	Cell division cycle 42.	Tyrosine-protein kinase.	0.439
CDC42	LOC107092854	ENSCVAP00000021883	ENSCVAP00000001486	Cell division cycle 42.	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.449
CDC42	LOC107096191	ENSCVAP00000021883	ENSCVAP00000002214	Cell division cycle 42.	Tyrosine-protein kinase.	0.483
CDC42	LOC107097814	ENSCVAP00000021883	ENSCVAP00000024831	Cell division cycle 42.	Uncharacterized protein.	0.449
CDC42	LOC107099902	ENSCVAP00000021883	ENSCVAP00000014970	Cell division cycle 42.	Uncharacterized protein.	0.449
CDC42	LOC107099926	ENSCVAP00000021883	ENSCVAP00000014231	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	LOC107099959	ENSCVAP00000021883	ENSCVAP00000027400	Cell division cycle 42.	Tyrosine-protein kinase.	0.439
CDC42	LOC107102211	ENSCVAP00000021883	ENSCVAP00000016437	Cell division cycle 42.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.653
CDC42	PAK2	ENSCVAP00000021883	ENSCVAP00000029676	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.940
CDC42	PAK3	ENSCVAP00000021883	ENSCVAP00000019890	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.958
CDC42	PIK3CA	ENSCVAP00000021883	ENSCVAP00000024569	Cell division cycle 42.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family.	0.653
CDC42	SRC	ENSCVAP00000021883	ENSCVAP00000009430	Cell division cycle 42.	Tyrosine-protein kinase.	0.523
CDC42	YES1	ENSCVAP00000021883	ENSCVAP00000002106	Cell division cycle 42.	Tyrosine-protein kinase.	0.439
CDC42	akt1	ENSCVAP00000021883	ENSCVAP00000011154	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.418
CDC42	fyn	ENSCVAP00000021883	ENSCVAP00000019767	Cell division cycle 42.	Tyrosine-protein kinase.	0.483
CDC42	grb2	ENSCVAP00000021883	ENSCVAP00000009535	Cell division cycle 42.	Growth factor receptor-bound protein 2b.	0.688
CDC42	lck	ENSCVAP00000021883	ENSCVAP00000030641	Cell division cycle 42.	Tyrosine-protein kinase.	0.439
CDC42	pak1	ENSCVAP00000021883	ENSCVAP00000024754	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.958