28 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107085991	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (854 aa)
	pak1	Non-specific serine/threonine protein kinase. (563 aa)
	limk1	Uncharacterized protein. (760 aa)
	LOC107100300	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (731 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (724 aa)
	PAK3	Non-specific serine/threonine protein kinase. (554 aa)
	fyn	Tyrosine-protein kinase. (537 aa)
	limk2	LIM domain kinase 2. (693 aa)
	ENSCVAP00000013536	Plexin_cytopl domain-containing protein. (167 aa)
	LOC107091972	Plexin A1a. (1880 aa)
	pak2	Non-specific serine/threonine protein kinase. (528 aa)
	LOC107091891	Plexin A2. (1900 aa)
	LOC107095492	Plexin A4. (1175 aa)
	LOC107100197	Sema domain-containing protein. (556 aa)
	PAK2	Non-specific serine/threonine protein kinase. (510 aa)
	Plxna2	Plexin_cytopl domain-containing protein. (165 aa)
	cfl1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (167 aa)
	ENSCVAP00000014486	Sema domain-containing protein. (509 aa)
	LOC107102251	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (161 aa)
	ENSCVAP00000015714	Uncharacterized protein. (81 aa)
	sema3b	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (727 aa)
	LOC107103990	LIM domain kinase 1a. (621 aa)
	LOC107099207	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (800 aa)
	plxna1	Plexin A1. (1893 aa)
	LOC107100299	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (724 aa)
	LOC107096191	Tyrosine-protein kinase. (537 aa)
	cfl2	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (924 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000013536	ENSCVAP00000014486	ENSCVAP00000013536	ENSCVAP00000014486	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.692
ENSCVAP00000013536	LOC107085991	ENSCVAP00000013536	ENSCVAP00000025317	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.598
ENSCVAP00000013536	LOC107099207	ENSCVAP00000013536	ENSCVAP00000019128	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	0.545
ENSCVAP00000013536	LOC107100197	ENSCVAP00000013536	ENSCVAP00000006544	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.636
ENSCVAP00000013536	nrp1	ENSCVAP00000013536	ENSCVAP00000028044	Plexin_cytopl domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.684
ENSCVAP00000013536	sema3b	ENSCVAP00000013536	ENSCVAP00000017471	Plexin_cytopl domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family.	0.604
ENSCVAP00000014486	ENSCVAP00000013536	ENSCVAP00000014486	ENSCVAP00000013536	Sema domain-containing protein.	Plexin_cytopl domain-containing protein.	0.692
ENSCVAP00000014486	LOC107085991	ENSCVAP00000014486	ENSCVAP00000025317	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.488
ENSCVAP00000014486	LOC107095492	ENSCVAP00000014486	ENSCVAP00000009639	Sema domain-containing protein.	Plexin A4.	0.829
ENSCVAP00000014486	LOC107099207	ENSCVAP00000014486	ENSCVAP00000019128	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	0.488
ENSCVAP00000014486	nrp1	ENSCVAP00000014486	ENSCVAP00000028044	Sema domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.657
ENSCVAP00000014486	sema3b	ENSCVAP00000014486	ENSCVAP00000017471	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family.	0.488
ENSCVAP00000015714	LOC107103990	ENSCVAP00000015714	ENSCVAP00000018392	Uncharacterized protein.	LIM domain kinase 1a.	0.560
ENSCVAP00000015714	PAK2	ENSCVAP00000015714	ENSCVAP00000029676	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.443
ENSCVAP00000015714	PAK3	ENSCVAP00000015714	ENSCVAP00000019890	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.433
ENSCVAP00000015714	limk1	ENSCVAP00000015714	ENSCVAP00000022964	Uncharacterized protein.	Uncharacterized protein.	0.538
ENSCVAP00000015714	limk2	ENSCVAP00000015714	ENSCVAP00000019621	Uncharacterized protein.	LIM domain kinase 2.	0.560
ENSCVAP00000015714	pak1	ENSCVAP00000015714	ENSCVAP00000024754	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.433
ENSCVAP00000015714	pak2	ENSCVAP00000015714	ENSCVAP00000012989	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.443
LOC107085991	ENSCVAP00000013536	ENSCVAP00000025317	ENSCVAP00000013536	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Plexin_cytopl domain-containing protein.	0.598