79 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107093789	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (580 aa)
	LOC107084246	cAMP responsive element binding protein 1. (313 aa)
	MAP2K6	Mitogen-activated protein kinase kinase 6. (335 aa)
	tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1. (506 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (416 aa)
	LOC107084368	Uncharacterized protein. (539 aa)
	dusp6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	LOC107101432	Mitogen-activated protein kinase. (360 aa)
	dusp3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (219 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (403 aa)
	LOC107102019	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
	MAPKAPK2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (319 aa)
	LOC107101533	Mitogen-activated protein kinase. (429 aa)
	rps27a	Ribosomal protein S27a. (181 aa)
	relch	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1212 aa)
	mapk8	Mitogen-activated protein kinase. (470 aa)
	fosl2	Fos-like antigen 2. (349 aa)
	map2k4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	fnbp4	Formin binding protein 4. (878 aa)
	LOC107094607	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	LOC107082069	Activating transcription factor 1. (311 aa)
	LOC107082142	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (497 aa)
	LOC107103739	JunE proto-oncogene, AP-1 transcription factor subunit. (332 aa)
	LOC107088346	Uncharacterized protein. (315 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	ENSCVAP00000024183	BZIP domain-containing protein. (122 aa)
	LOC107095042	SEFIR domain-containing protein. (485 aa)
	vrk3	VRK serine/threonine kinase 3. (511 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	creb5	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (494 aa)
	LOC107088171	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (393 aa)
	LOC107088073	Ribosomal protein S6 kinase. (779 aa)
	LOC107090256	SEFIR domain-containing protein. (723 aa)
	LOC107103198	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	LOC107097013	ETS transcription factor ELK1. (547 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (460 aa)
	LOC107091383	Ribosomal protein S6 kinase. (782 aa)
	LOC107085741	Sterile alpha motif and leucine zipper containing kinase AZK. (793 aa)
	atf2	Activating transcription factor 2. (513 aa)
	LOC107084094	Ribosomal protein S6 kinase. (746 aa)
	ENSCVAP00000030880	Uncharacterized protein. (141 aa)
	LOC107097523	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (484 aa)
	LOC107102050	Mitogen-activated protein kinase. (420 aa)
	ENSCVAP00000031090	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (264 aa)
	map3k20	Protein kinase domain-containing protein. (698 aa)
	tab3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (598 aa)
	mapk15	Mitogen-activated protein kinase. (601 aa)
	LOC107090723	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	LOC107092405	V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (367 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (314 aa)
	nod1	Nucleotide-binding oligomerization domain containing 1. (921 aa)
	LOC107088576	Mitogen-activated protein kinase. (364 aa)
	LOC107095820	Ribosomal protein S6 kinase. (803 aa)
	LOC107083139	V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (363 aa)
	tab2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (752 aa)
	ENSCVAP00000020427	Interleukin 17a/f1. (156 aa)
	irak1	Interleukin-1 receptor-associated kinase 1. (708 aa)
	LOC107096251	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
	LOC107104997	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (218 aa)
	ENSCVAP00000021667	Ubiquitin-like domain-containing protein. (83 aa)
	LOC107095673	Interleukin 17a/f3. (160 aa)
	asb8	Activating transcription factor 7a. (573 aa)
	mapk7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1095 aa)
	LOC107103559	Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	ppp4r1	WRNPLPNID domain-containing protein. (975 aa)
	creb1	cAMP responsive element binding protein 1a. (331 aa)
	mapk1	Mitogen-activated protein kinase. (351 aa)
	ppp4r4	Protein phosphatase 4, regulatory subunit 4. (749 aa)
	LOC107084657	Serine/threonine-protein phosphatase. (309 aa)
	LOC107090247	Mitogen-activated protein kinase kinase 6. (358 aa)
	mapk10	Mitogen-activated protein kinase. (425 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
	LOC107101186	Mitogen-activated protein kinase. (379 aa)
	ENSCVAP00000012952	Uncharacterized protein. (601 aa)
	ENSCVAP00000011893	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (305 aa)
	LOC107085894	Serine/threonine-protein phosphatase. (309 aa)
	LOC107101279	Mitogen-activated protein kinase 11. (293 aa)
	LOC107087504	Mitogen-activated protein kinase. (357 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000011893	ENSCVAP00000021667	ENSCVAP00000011893	ENSCVAP00000021667	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ubiquitin-like domain-containing protein.	0.521
ENSCVAP00000011893	LOC107090247	ENSCVAP00000011893	ENSCVAP00000014052	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 6.	0.794
ENSCVAP00000011893	LOC107090723	ENSCVAP00000011893	ENSCVAP00000031618	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ubiquitin-conjugating enzyme E2 variant 1.	0.536
ENSCVAP00000011893	LOC107093789	ENSCVAP00000011893	ENSCVAP00000010683	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.440
ENSCVAP00000011893	LOC107094607	ENSCVAP00000011893	ENSCVAP00000001617	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.873
ENSCVAP00000011893	LOC107096251	ENSCVAP00000011893	ENSCVAP00000020745	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	0.830
ENSCVAP00000011893	LOC107103559	ENSCVAP00000011893	ENSCVAP00000023217	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family.	0.873
ENSCVAP00000011893	MAP2K6	ENSCVAP00000011893	ENSCVAP00000010075	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 6.	0.794
ENSCVAP00000011893	RIPK2	ENSCVAP00000011893	ENSCVAP00000030122	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Receptor interacting serine/threonine kinase 2.	0.706
ENSCVAP00000011893	irak1	ENSCVAP00000011893	ENSCVAP00000020487	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Interleukin-1 receptor-associated kinase 1.	0.713
ENSCVAP00000011893	map2k4	ENSCVAP00000011893	ENSCVAP00000002373	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.830
ENSCVAP00000011893	map2k7	ENSCVAP00000011893	ENSCVAP00000008899	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 7.	0.749
ENSCVAP00000011893	nod1	ENSCVAP00000011893	ENSCVAP00000018896	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Nucleotide-binding oligomerization domain containing 1.	0.425
ENSCVAP00000011893	rps27a	ENSCVAP00000011893	ENSCVAP00000003612	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ribosomal protein S27a.	0.581
ENSCVAP00000011893	tab1	ENSCVAP00000011893	ENSCVAP00000009386	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TGF-beta activated kinase 1/MAP3K7 binding protein 1.	0.974
ENSCVAP00000011893	tab2	ENSCVAP00000011893	ENSCVAP00000020013	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.823
ENSCVAP00000011893	tab3	ENSCVAP00000011893	ENSCVAP00000031343	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.958
ENSCVAP00000011893	traf6	ENSCVAP00000011893	ENSCVAP00000013118	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.974
ENSCVAP00000011893	uba52	ENSCVAP00000011893	ENSCVAP00000025559	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.614
ENSCVAP00000012952	ENSCVAP00000020427	ENSCVAP00000012952	ENSCVAP00000020427	Uncharacterized protein.	Interleukin 17a/f1.	0.509