12 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	Fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	LOC107101473	Alpha_adaptinC2 domain-containing protein. (841 aa)
	ENSCVAP00000023340	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
	LOC107103921	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (948 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
	ENSCVAP00000012583	Uncharacterized protein. (58 aa)
	cltb	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (197 aa)
	ror1	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (950 aa)
	ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
	Fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (560 aa)
	LOC107090293	AP complex subunit beta. (919 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000012583	LOC107101473	ENSCVAP00000012583	ENSCVAP00000023523	Uncharacterized protein.	Alpha_adaptinC2 domain-containing protein.	0.887
ENSCVAP00000012583	LOC107103921	ENSCVAP00000012583	ENSCVAP00000021034	Uncharacterized protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.925
ENSCVAP00000012583	ap2m1	ENSCVAP00000012583	ENSCVAP00000031359	Uncharacterized protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.949
ENSCVAP00000012583	ap2s1	ENSCVAP00000012583	ENSCVAP00000017307	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.947
ENSCVAP00000012583	clta	ENSCVAP00000012583	ENSCVAP00000017055	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.855
ENSCVAP00000012583	cltb	ENSCVAP00000012583	ENSCVAP00000011855	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.763
ENSCVAP00000023340	ror1	ENSCVAP00000023340	ENSCVAP00000001621	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.952
Fzd5	ror1	ENSCVAP00000030032	ENSCVAP00000001621	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.952
Fzd8	ror1	ENSCVAP00000024220	ENSCVAP00000001621	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.952
LOC107090293	LOC107101473	ENSCVAP00000028162	ENSCVAP00000023523	AP complex subunit beta.	Alpha_adaptinC2 domain-containing protein.	0.925
LOC107090293	LOC107103921	ENSCVAP00000028162	ENSCVAP00000021034	AP complex subunit beta.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.992
LOC107090293	ap2m1	ENSCVAP00000028162	ENSCVAP00000031359	AP complex subunit beta.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.994
LOC107090293	ap2s1	ENSCVAP00000028162	ENSCVAP00000017307	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.994
LOC107090293	clta	ENSCVAP00000028162	ENSCVAP00000017055	AP complex subunit beta.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.969
LOC107090293	cltb	ENSCVAP00000028162	ENSCVAP00000011855	AP complex subunit beta.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.842
LOC107101473	ENSCVAP00000012583	ENSCVAP00000023523	ENSCVAP00000012583	Alpha_adaptinC2 domain-containing protein.	Uncharacterized protein.	0.887
LOC107101473	LOC107090293	ENSCVAP00000023523	ENSCVAP00000028162	Alpha_adaptinC2 domain-containing protein.	AP complex subunit beta.	0.925
LOC107101473	LOC107103921	ENSCVAP00000023523	ENSCVAP00000021034	Alpha_adaptinC2 domain-containing protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.679
LOC107101473	ap2m1	ENSCVAP00000023523	ENSCVAP00000031359	Alpha_adaptinC2 domain-containing protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.995
LOC107101473	ap2s1	ENSCVAP00000023523	ENSCVAP00000017307	Alpha_adaptinC2 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.995