35 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vav2	Vav 2 guanine nucleotide exchange factor. (879 aa)
	LOC107099926	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	stx12	Syntaxin 12; Belongs to the syntaxin family. (259 aa)
	ENSCVAP00000032381	WD_REPEATS_REGION domain-containing protein. (68 aa)
	stx7	Syntaxin 7-like; Belongs to the syntaxin family. (255 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	LOC107090777	Junction plakoglobin a. (724 aa)
	PAK2	Non-specific serine/threonine protein kinase. (510 aa)
	ENSCVAP00000029198	V-akt murine thymoma viral oncogene homolog 3b. (181 aa)
	pak1	Non-specific serine/threonine protein kinase. (563 aa)
	LOC107088920	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (781 aa)
	LOC107100300	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (731 aa)
	LOC107096308	Thioesterase superfamily member 4. (245 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2406 aa)
	ctnnd1	Catenin (cadherin-associated protein), delta 1. (929 aa)
	LOC107093336	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
	PAK3	Non-specific serine/threonine protein kinase. (554 aa)
	ENSCVAP00000019147	WD_REPEATS_REGION domain-containing protein. (66 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae). (260 aa)
	CTNND1	Catenin delta 1. (917 aa)
	LOC107083482	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
	LOC107097675	Uncharacterized protein. (831 aa)
	LOC107101293	Uncharacterized protein. (768 aa)
	ARVCF	ARVCF delta catenin family member b. (947 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC107100299	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (724 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1724 aa)
	LOC107093166	Tribbles pseudokinase 3. (350 aa)
	pak2	Non-specific serine/threonine protein kinase. (528 aa)
	LOC107085917	Vav 3 guanine nucleotide exchange factor b. (794 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (843 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	LOC107103532	MAPK associated protein 1. (486 aa)
	LOC107095985	Uncharacterized protein. (350 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARVCF	LOC107085917	ENSCVAP00000006980	ENSCVAP00000010329	ARVCF delta catenin family member b.	Vav 3 guanine nucleotide exchange factor b.	0.445
ARVCF	LOC107088920	ENSCVAP00000006980	ENSCVAP00000022905	ARVCF delta catenin family member b.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.791
ARVCF	LOC107090777	ENSCVAP00000006980	ENSCVAP00000030699	ARVCF delta catenin family member b.	Junction plakoglobin a.	0.718
ARVCF	LOC107097675	ENSCVAP00000006980	ENSCVAP00000009948	ARVCF delta catenin family member b.	Uncharacterized protein.	0.445
ARVCF	LOC107101293	ENSCVAP00000006980	ENSCVAP00000009659	ARVCF delta catenin family member b.	Uncharacterized protein.	0.637
ARVCF	PAK2	ENSCVAP00000006980	ENSCVAP00000029676	ARVCF delta catenin family member b.	Non-specific serine/threonine protein kinase.	0.454
ARVCF	PAK3	ENSCVAP00000006980	ENSCVAP00000019890	ARVCF delta catenin family member b.	Non-specific serine/threonine protein kinase.	0.453
ARVCF	VAV1	ENSCVAP00000006980	ENSCVAP00000010575	ARVCF delta catenin family member b.	Vav guanine nucleotide exchange factor 1.	0.445
ARVCF	ctnnb1	ENSCVAP00000006980	ENSCVAP00000031623	ARVCF delta catenin family member b.	Catenin (cadherin-associated protein), beta 1.	0.835
ARVCF	pak1	ENSCVAP00000006980	ENSCVAP00000024754	ARVCF delta catenin family member b.	Non-specific serine/threonine protein kinase.	0.453
ARVCF	pak2	ENSCVAP00000006980	ENSCVAP00000012989	ARVCF delta catenin family member b.	Non-specific serine/threonine protein kinase.	0.454
ARVCF	vav2	ENSCVAP00000006980	ENSCVAP00000013906	ARVCF delta catenin family member b.	Vav 2 guanine nucleotide exchange factor.	0.445
CTNND1	LOC107085917	ENSCVAP00000017959	ENSCVAP00000010329	Catenin delta 1.	Vav 3 guanine nucleotide exchange factor b.	0.445
CTNND1	LOC107088920	ENSCVAP00000017959	ENSCVAP00000022905	Catenin delta 1.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.791
CTNND1	LOC107090777	ENSCVAP00000017959	ENSCVAP00000030699	Catenin delta 1.	Junction plakoglobin a.	0.718
CTNND1	LOC107097675	ENSCVAP00000017959	ENSCVAP00000009948	Catenin delta 1.	Uncharacterized protein.	0.445
CTNND1	LOC107101293	ENSCVAP00000017959	ENSCVAP00000009659	Catenin delta 1.	Uncharacterized protein.	0.637
CTNND1	PAK2	ENSCVAP00000017959	ENSCVAP00000029676	Catenin delta 1.	Non-specific serine/threonine protein kinase.	0.454
CTNND1	PAK3	ENSCVAP00000017959	ENSCVAP00000019890	Catenin delta 1.	Non-specific serine/threonine protein kinase.	0.453
CTNND1	VAV1	ENSCVAP00000017959	ENSCVAP00000010575	Catenin delta 1.	Vav guanine nucleotide exchange factor 1.	0.445