17 items (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	LOC107095138	Zgc:55558. (187 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	prkcz	Protein kinase C, zeta. (513 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1310 aa)
	SRC	Tyrosine-protein kinase. (551 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1207 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1234 aa)
	LOC107091507	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (700 aa)
	ENSCVAP00000028612	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	LOC107088081	DAGKc domain-containing protein. (562 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1048 aa)
	SPHK1	Sphingosine kinase 1. (356 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (907 aa)
	prkcd	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC107091507	ENSCVAP00000000427	ENSCVAP00000011129	Cold shock domain containing E1, RNA-binding.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.511
CSDE1	pdpk1	ENSCVAP00000000427	ENSCVAP00000019109	Cold shock domain containing E1, RNA-binding.	3-phosphoinositide dependent protein kinase 1b.	0.507
CSDE1	prkcd	ENSCVAP00000000427	ENSCVAP00000003980	Cold shock domain containing E1, RNA-binding.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.511
CSDE1	prkcz	ENSCVAP00000000427	ENSCVAP00000005661	Cold shock domain containing E1, RNA-binding.	Protein kinase C, zeta.	0.473
CSDE1	rasa1	ENSCVAP00000000427	ENSCVAP00000032034	Cold shock domain containing E1, RNA-binding.	RAS p21 protein activator (GTPase activating protein) 1a.	0.805
ENSCVAP00000028612	vegfa	ENSCVAP00000028612	ENSCVAP00000023279	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.900
KRAS	LOC107091507	ENSCVAP00000004733	ENSCVAP00000011129	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.511
KRAS	LOC107095138	ENSCVAP00000004733	ENSCVAP00000004689	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Zgc:55558.	0.901
KRAS	SRC	ENSCVAP00000004733	ENSCVAP00000009430	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Tyrosine-protein kinase.	0.434
KRAS	hras	ENSCVAP00000004733	ENSCVAP00000007057	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	HRas proto-oncogene, GTPase a.	0.910
KRAS	pdpk1	ENSCVAP00000004733	ENSCVAP00000019109	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	3-phosphoinositide dependent protein kinase 1b.	0.507
KRAS	prkcd	ENSCVAP00000004733	ENSCVAP00000003980	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.511
KRAS	prkcz	ENSCVAP00000004733	ENSCVAP00000005661	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	Protein kinase C, zeta.	0.473
KRAS	rasa1	ENSCVAP00000004733	ENSCVAP00000032034	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	RAS p21 protein activator (GTPase activating protein) 1a.	0.979
LOC107088081	prkcz	ENSCVAP00000027996	ENSCVAP00000005661	DAGKc domain-containing protein.	Protein kinase C, zeta.	0.481
LOC107091507	CSDE1	ENSCVAP00000011129	ENSCVAP00000000427	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Cold shock domain containing E1, RNA-binding.	0.511
LOC107091507	KRAS	ENSCVAP00000011129	ENSCVAP00000004733	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.511
LOC107091507	LOC107095138	ENSCVAP00000011129	ENSCVAP00000004689	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Zgc:55558.	0.511
LOC107091507	hras	ENSCVAP00000011129	ENSCVAP00000007057	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	HRas proto-oncogene, GTPase a.	0.511
LOC107091507	pdpk1	ENSCVAP00000011129	ENSCVAP00000019109	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	3-phosphoinositide dependent protein kinase 1b.	0.737