37 items (Cyprinodon variegatus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
	ENSCVAP00000000999	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (167 aa)
	Fgf4	Fibroblast growth factor 4. (144 aa)
	rps27a	Ribosomal protein S27a. (181 aa)
	LOC107089939	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (172 aa)
	ENSCVAP00000008530	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (183 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	SRC	Tyrosine-protein kinase. (551 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	LOC107089165	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC107101770	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (226 aa)
	LOC107085894	Serine/threonine-protein phosphatase. (309 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC107101186	Mitogen-activated protein kinase. (379 aa)
	LOC107098202	Uncharacterized protein. (860 aa)
	LOC107084657	Serine/threonine-protein phosphatase. (309 aa)
	mapk1	Mitogen-activated protein kinase. (351 aa)
	LOC107101656	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (160 aa)
	LOC107082377	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1207 aa)
	ENSCVAP00000018644	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	mknk1	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (461 aa)
	ENSCVAP00000022018	Uncharacterized protein. (54 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (952 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC107088237	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (531 aa)
	LOC107090307	Sprouty RTK signaling antagonist 2. (351 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (276 aa)
	LOC107083535	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (566 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1234 aa)
	fgf20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa)
	LOC107096942	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (314 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCVAP00000000999	LOC107096942	ENSCVAP00000000999	ENSCVAP00000032467	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.512
ENSCVAP00000000999	LOC107101770	ENSCVAP00000000999	ENSCVAP00000011263	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.573
ENSCVAP00000000999	fgf23	ENSCVAP00000000999	ENSCVAP00000028227	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.590
ENSCVAP00000000999	grb2	ENSCVAP00000000999	ENSCVAP00000009535	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Growth factor receptor-bound protein 2b.	0.489
ENSCVAP00000000999	rps27a	ENSCVAP00000000999	ENSCVAP00000003612	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Ribosomal protein S27a.	0.517
ENSCVAP00000000999	uba52	ENSCVAP00000000999	ENSCVAP00000025559	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.463
ENSCVAP00000008530	LOC107089939	ENSCVAP00000008530	ENSCVAP00000007289	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.428
ENSCVAP00000008530	LOC107096942	ENSCVAP00000008530	ENSCVAP00000032467	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.512
ENSCVAP00000008530	LOC107101656	ENSCVAP00000008530	ENSCVAP00000015898	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.427
ENSCVAP00000008530	LOC107101770	ENSCVAP00000008530	ENSCVAP00000011263	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.573
ENSCVAP00000008530	fgf23	ENSCVAP00000008530	ENSCVAP00000028227	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.590
ENSCVAP00000008530	grb2	ENSCVAP00000008530	ENSCVAP00000009535	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Growth factor receptor-bound protein 2b.	0.489
ENSCVAP00000008530	rps27a	ENSCVAP00000008530	ENSCVAP00000003612	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Ribosomal protein S27a.	0.517
ENSCVAP00000008530	uba52	ENSCVAP00000008530	ENSCVAP00000025559	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.463
ENSCVAP00000018644	LOC107083535	ENSCVAP00000018644	ENSCVAP00000028276	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.409
ENSCVAP00000018644	LOC107096942	ENSCVAP00000018644	ENSCVAP00000032467	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.424
ENSCVAP00000018644	LOC107098202	ENSCVAP00000018644	ENSCVAP00000013317	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.409
ENSCVAP00000018644	LOC107101770	ENSCVAP00000018644	ENSCVAP00000011263	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.537
ENSCVAP00000018644	cbl	ENSCVAP00000018644	ENSCVAP00000023904	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.409
ENSCVAP00000018644	fgf23	ENSCVAP00000018644	ENSCVAP00000028227	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.589